FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4327710725> ?p ?o ?g. }

• W4327710725 endingPage "009121742311646" @default.
• W4327710725 startingPage "009121742311646" @default.
• W4327710725 abstract "Genetic factors play an important role in the etiology of schizophrenia (SZ). Catenin Delta 2 (CTNND2) is one of the genes regulating neuronal development in the brain. It is unclear whether CTNND2 is involved in SZ. With the hypothesis that CTNND2 may be a risk gene for SZ, we performed a case-control association analysis to investigate if CTNND2 gene single nucleotide polymorphisms (SNPs) are implicated in SZ in a Han Chinese population.We recruited subjects from 2010 to 2022 from the Han population of northern Henan and divided them into two case-control samples, including a discovery sample (SZ = 528 and controls = 528) and replication sample (SZ = 2458 and controls = 6914). Twenty-one SNPs were genotyped on the Illumina BeadStation 500G platform using GoldenGate technology and analyzed by PLINK. The Positive and Negative Syndrome Scale (PANSS) was used to assess clinical symptoms.Rs16901943, rs7733427, and rs2168878 SNPs were associated with SZ (Chi2 = 7.484, 11.576, and 5.391, respectively, df = 1; p = 0.006, 0.00067, and 0.02, respectively) in the two samples. Rs10058868 was associated with SZ in male patients in the discovery sample (Chi2 = 6.264, df = 1, p = .044). Only the relationship with rs7733427 survived Bonferroni correction. Linkage disequilibrium block three haplotypes were associated with SZ in the discovery and total sample. PANSS analysis of the four SNPs implicated rs10058868 and rs2168878 in symptoms of depression and excitement, respectively, in the patients with SZ.Four SNPs of the CTNND2 gene were identified as being correlated with SZ. This gene may be involved in susceptibility to SZ." @default.
• W4327710725 created "2023-03-18" @default.
• W4327710725 creator A5011308222 @default.
• W4327710725 creator A5017941291 @default.
• W4327710725 creator A5028032974 @default.
• W4327710725 creator A5029225084 @default.
• W4327710725 creator A5041170278 @default.
• W4327710725 creator A5045200319 @default.
• W4327710725 creator A5052340036 @default.
• W4327710725 creator A5061100241 @default.
• W4327710725 creator A5067604625 @default.
• W4327710725 creator A5087699676 @default.
• W4327710725 creator A5088424906 @default.
• W4327710725 creator A5090009016 @default.
• W4327710725 date "2023-03-17" @default.
• W4327710725 modified "2023-10-16" @default.
• W4327710725 title "Association of CTNND2 gene polymorphism with schizophrenia: Two-sample case-control study in Chinese Han population" @default.
• W4327710725 cites W1907802063 @default.
• W4327710725 cites W1969833650 @default.
• W4327710725 cites W1972398850 @default.
• W4327710725 cites W1976408965 @default.
• W4327710725 cites W1984203471 @default.
• W4327710725 cites W2002231678 @default.
• W4327710725 cites W2015408724 @default.
• W4327710725 cites W2030447006 @default.
• W4327710725 cites W2032523288 @default.
• W4327710725 cites W2060801754 @default.
• W4327710725 cites W2076805502 @default.
• W4327710725 cites W2101357408 @default.
• W4327710725 cites W2125343575 @default.
• W4327710725 cites W2132853326 @default.
• W4327710725 cites W2149385661 @default.
• W4327710725 cites W2160859576 @default.
• W4327710725 cites W2162530578 @default.
• W4327710725 cites W2166722062 @default.
• W4327710725 cites W2216192257 @default.
• W4327710725 cites W2475276186 @default.
• W4327710725 cites W2511267207 @default.
• W4327710725 cites W2546600114 @default.
• W4327710725 cites W2609984900 @default.
• W4327710725 cites W2737744488 @default.
• W4327710725 cites W2761275051 @default.
• W4327710725 cites W2782018768 @default.
• W4327710725 cites W2782433136 @default.
• W4327710725 cites W2790195606 @default.
• W4327710725 cites W2886649144 @default.
• W4327710725 cites W2901303766 @default.
• W4327710725 cites W2916226351 @default.
• W4327710725 cites W2921462169 @default.
• W4327710725 cites W2949785910 @default.
• W4327710725 cites W2982685163 @default.
• W4327710725 cites W2983765585 @default.
• W4327710725 cites W2999666198 @default.
• W4327710725 cites W3017691062 @default.
• W4327710725 cites W3042410003 @default.
• W4327710725 cites W3048815043 @default.
• W4327710725 cites W3089289985 @default.
• W4327710725 cites W3089565459 @default.
• W4327710725 cites W3089592748 @default.
• W4327710725 cites W3091369933 @default.
• W4327710725 cites W3127806496 @default.
• W4327710725 cites W3130932978 @default.
• W4327710725 cites W3157595167 @default.
• W4327710725 cites W3159776694 @default.
• W4327710725 cites W3199976399 @default.
• W4327710725 cites W3208652066 @default.
• W4327710725 cites W4200432987 @default.
• W4327710725 cites W4211174138 @default.
• W4327710725 cites W4223520055 @default.
• W4327710725 cites W4281731300 @default.
• W4327710725 cites W4284891855 @default.
• W4327710725 cites W4315786171 @default.
• W4327710725 cites W4318667506 @default.
• W4327710725 cites W4318775160 @default.
• W4327710725 doi "https://doi.org/10.1177/00912174231164669" @default.
• W4327710725 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36930964" @default.
• W4327710725 hasPublicationYear "2023" @default.
• W4327710725 type Work @default.
• W4327710725 citedByCount "0" @default.
• W4327710725 crossrefType "journal-article" @default.
• W4327710725 hasAuthorship W4327710725A5011308222 @default.
• W4327710725 hasAuthorship W4327710725A5017941291 @default.
• W4327710725 hasAuthorship W4327710725A5028032974 @default.
• W4327710725 hasAuthorship W4327710725A5029225084 @default.
• W4327710725 hasAuthorship W4327710725A5041170278 @default.
• W4327710725 hasAuthorship W4327710725A5045200319 @default.
• W4327710725 hasAuthorship W4327710725A5052340036 @default.
• W4327710725 hasAuthorship W4327710725A5061100241 @default.
• W4327710725 hasAuthorship W4327710725A5067604625 @default.
• W4327710725 hasAuthorship W4327710725A5087699676 @default.
• W4327710725 hasAuthorship W4327710725A5088424906 @default.
• W4327710725 hasAuthorship W4327710725A5090009016 @default.
• W4327710725 hasConcept C104317684 @default.
• W4327710725 hasConcept C105795698 @default.
• W4327710725 hasConcept C118552586 @default.
• W4327710725 hasConcept C126322002 @default.
• W4327710725 hasConcept C127808970 @default.
• W4327710725 hasConcept C135763542 @default.

• next