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• W4327716498 abstract "Scientists have recently discovered a link between the circulating microbiome and homeostasis, as well as the pathogenesis of a number of metabolic diseases. It has been demonstrated that low-grade chronic inflammation is one of the primary mechanisms that has long been implicated in the risk of cardio-metabolic disease (CMDs) and its progression. Currently, the dysbiosis of circulating bacteria is considered as a key regulator for chronic inflammation in CMDs, which is why we have conducted this systemic review focused on circulating bacterial dysbiosis.A systemic review of clinical and research-based studies was conducted via PubMed, Scopus, Medline, and Web of Science. Literature was considered for risk of bias and patterns of intervention effects. A randomized effect model was used to evaluate the dysbiosis of circulating microbiota and clinical outcomes. We conducted a meta-analysis considering the circulating bacteria in both healthy people and people with cardio-metabolic disorders, in reports published mainly from 2008 to 2022, according to the PRISMA guidelines.We searched 627 studies and, after completing the risk of bias and selection, 31 studies comprising of 11,132 human samples were considered. This meta-analysis found that dysbiosis of phyla Proteobacteria, Firmicutes, and Bacteroidetes was associated with metabolic diseases.In most instances, metabolic diseases are linked to higher diversity and elevated bacterial DNA levels. Bacteroides abundance was higher in healthy people than with metabolic disorders. However, more rigorous studies are required to determine the role of bacterial dysbiosis in cardio-metabolic diseases. Understanding the relationship between dysbiosis and cardio-metabolic diseases, we can use the bacteria as therapeutics for the reversal of dysbiosis and targets for therapeutics use in cardio-metabolic diseases. In the future, circulating bacterial signatures can be used as biomarkers for the early detection of metabolic diseases." @default.
• W4327716498 created "2023-03-18" @default.
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• W4327716498 date "2023-03-17" @default.
• W4327716498 modified "2023-09-29" @default.
• W4327716498 title "Blood Stream Microbiota Dysbiosis Establishing New Research Standards in Cardio-Metabolic Diseases, A Meta-Analysis Study" @default.
• W4327716498 cites W1535151445 @default.
• W4327716498 cites W1672101516 @default.
• W4327716498 cites W1988238720 @default.
• W4327716498 cites W1992529581 @default.
• W4327716498 cites W1998365634 @default.
• W4327716498 cites W2001172144 @default.
• W4327716498 cites W2005501262 @default.
• W4327716498 cites W2006259699 @default.
• W4327716498 cites W2014799977 @default.
• W4327716498 cites W2021951363 @default.
• W4327716498 cites W2022712156 @default.
• W4327716498 cites W2050168569 @default.
• W4327716498 cites W2066283695 @default.
• W4327716498 cites W2068629997 @default.
• W4327716498 cites W2072515653 @default.
• W4327716498 cites W2076728075 @default.
• W4327716498 cites W2098923148 @default.
• W4327716498 cites W2105234132 @default.
• W4327716498 cites W2107616906 @default.
• W4327716498 cites W2110743053 @default.
• W4327716498 cites W2115763995 @default.
• W4327716498 cites W2130483595 @default.
• W4327716498 cites W2130603879 @default.
• W4327716498 cites W2131536322 @default.
• W4327716498 cites W2133017002 @default.
• W4327716498 cites W2135989088 @default.
• W4327716498 cites W2138345878 @default.
• W4327716498 cites W2143429993 @default.
• W4327716498 cites W2147955113 @default.
• W4327716498 cites W2268501839 @default.
• W4327716498 cites W2272721999 @default.
• W4327716498 cites W2523689809 @default.
• W4327716498 cites W2539186102 @default.
• W4327716498 cites W2588681363 @default.
• W4327716498 cites W2593856047 @default.
• W4327716498 cites W2766754487 @default.
• W4327716498 cites W2790364467 @default.
• W4327716498 cites W2791637468 @default.
• W4327716498 cites W2791786910 @default.
• W4327716498 cites W2805388193 @default.
• W4327716498 cites W2891509908 @default.
• W4327716498 cites W2900722595 @default.
• W4327716498 cites W2914091352 @default.
• W4327716498 cites W2936693879 @default.
• W4327716498 cites W2943903553 @default.
• W4327716498 cites W2949787012 @default.
• W4327716498 cites W2952874835 @default.
• W4327716498 cites W2959992540 @default.
• W4327716498 cites W2969477910 @default.
• W4327716498 cites W2971039710 @default.
• W4327716498 cites W2976983115 @default.
• W4327716498 cites W2977135463 @default.
• W4327716498 cites W2982095812 @default.
• W4327716498 cites W2982752464 @default.
• W4327716498 cites W2984350996 @default.
• W4327716498 cites W2995284626 @default.
• W4327716498 cites W3003147142 @default.
• W4327716498 cites W3005755138 @default.
• W4327716498 cites W3009443760 @default.
• W4327716498 cites W3010810358 @default.
• W4327716498 cites W3017206405 @default.
• W4327716498 cites W3026172159 @default.
• W4327716498 cites W3048464682 @default.
• W4327716498 cites W3083583215 @default.
• W4327716498 cites W3105027508 @default.
• W4327716498 cites W3109194399 @default.
• W4327716498 cites W3166070092 @default.
• W4327716498 cites W3173621753 @default.
• W4327716498 cites W3177455496 @default.
• W4327716498 cites W3182034478 @default.
• W4327716498 cites W3183896543 @default.
• W4327716498 cites W3197217935 @default.
• W4327716498 cites W4211190087 @default.
• W4327716498 cites W4220981348 @default.
• W4327716498 cites W4225388759 @default.
• W4327716498 cites W4281477687 @default.
• W4327716498 cites W4282946113 @default.
• W4327716498 cites W4283365059 @default.
• W4327716498 cites W4285719527 @default.
• W4327716498 cites W4288925027 @default.
• W4327716498 cites W4292878047 @default.
• W4327716498 cites W4300818892 @default.
• W4327716498 doi "https://doi.org/10.3390/microorganisms11030777" @default.
• W4327716498 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36985350" @default.
• W4327716498 hasPublicationYear "2023" @default.
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