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- W4327725009 abstract "Abstract Background: Thanks to the introduction of radiomics, 3d reconstruction can be able to analyse tissues and recognise true hypertrophy from non-functioning tissue in patients treated with major hepatectomies with hepatic modulation.The aim of this study is to evaluate the performance of 3D Imaging Modelling in predict liver failure. Methods: Patients submitted to major hepatectomies after hepatic modulation at Sanchinarro University Hospital from May 2015 to October 2019 were analysed. Three dimensional reconstruction was realised before and after surgical treatment. The volumetry of Future Liver Remnant was calculated, distinguishing in Functional Future Liver Remnant (FRFx) i.e. true hypertrophy tissue and Anatomic Future Liver Remnant (FRL) i.e. hypertrophy plus no functional tissue (edema/congestion) These volumeswere analysed in patients with and without post hepatic liver failure. Results: Twenty-four procedures were realised (11 ALPPS and 13 PVE followed by major hepatectomy). Post hepatic liver failure grade B and C occurred in 6 patients. The ROC curve showed a better AUC for FRFxV (74%) with respect to FRLV (54%) in prediction PHLF>B. The increase of anatomical FRL (iFRL) was superior in the ALPPS group (120%) with respect to the PVE group (73%) (p=0,041), while the increase of functional FRFX (iFRFx) was 35% in the ALLPS group and 46% in the PVE group (p>0,05), showing no difference in the two groups. Conclusion: The 3D reconstruction model can allow optimal surgical planning, and through the use of specific algorithms, can contribute to differential functioning liver parenchyma of the FLR." @default.
- W4327725009 created "2023-03-18" @default.
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- W4327725009 date "2023-03-17" @default.
- W4327725009 modified "2023-10-16" @default.
- W4327725009 title "Can 3D Imaging Modeling Recognize Functional Tissue and Predict Liver Failure? A retrospective study based on 3D modelling of the major hepatectomies after hepatic modulation." @default.
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- W4327725009 doi "https://doi.org/10.21203/rs.3.rs-2627518/v1" @default.
- W4327725009 hasPublicationYear "2023" @default.
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