FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4327733339> ?p ?o ?g. }

• W4327733339 abstract "Anaplastic thyroid carcinoma (ATC) is a rare and aggressive form of thyroid carcinoma (TC). Currently, there are no effective treatments for this condition. In the past few years, targeted therapy and immunotherapy have made significant progress in ATC treatment. Several common genetic mutations have been found in ATC cells, involving different molecular pathways related to tumor progression, and new therapies that act on these molecular pathways have been studied to improve the quality of life of these patients. In 2018, the FDA approved dabrafenib combined with trametinib to treat BRAF-positive ATC, confirming its therapeutic potential. At the same time, the recent emergence of immunotherapy has also attracted wide attention from researchers. While immunotherapy for ATC is still in the experimental stage, numerous studies have shown that immunotherapy is a potential therapy for ATC. In addition, it has also been found that the combination of immunotherapy and targeted therapy may enhance the anti-tumor effect of targeted therapy. In recent years, there has been some progress in the study of targeted therapy or immunotherapy combined with radiotherapy or chemotherapy, showing the prospect of combined therapy in ATC. In this review, we analyze the response mechanism and potential effects of targeted therapy, immunotherapy, and combination therapy in ATC treatment and explore the future of treatment for ATC." @default.
• W4327733339 created "2023-03-18" @default.
• W4327733339 creator A5056770759 @default.
• W4327733339 creator A5066251950 @default.
• W4327733339 creator A5071784610 @default.
• W4327733339 creator A5090570350 @default.
• W4327733339 date "2023-03-17" @default.
• W4327733339 modified "2023-09-25" @default.
• W4327733339 title "Immunotherapy or targeted therapy: What will be the future treatment for anaplastic thyroid carcinoma?" @default.
• W4327733339 cites W1846586690 @default.
• W4327733339 cites W1942136308 @default.
• W4327733339 cites W1977731422 @default.
• W4327733339 cites W1989847073 @default.
• W4327733339 cites W1989932167 @default.
• W4327733339 cites W1990004382 @default.
• W4327733339 cites W1990602451 @default.
• W4327733339 cites W2020822273 @default.
• W4327733339 cites W2024936926 @default.
• W4327733339 cites W2034116169 @default.
• W4327733339 cites W2046972425 @default.
• W4327733339 cites W2052874737 @default.
• W4327733339 cites W2061282370 @default.
• W4327733339 cites W2066671159 @default.
• W4327733339 cites W2072380594 @default.
• W4327733339 cites W2085932739 @default.
• W4327733339 cites W2087013294 @default.
• W4327733339 cites W2091494856 @default.
• W4327733339 cites W2092228104 @default.
• W4327733339 cites W2092878233 @default.
• W4327733339 cites W2095667451 @default.
• W4327733339 cites W2105743205 @default.
• W4327733339 cites W2113134419 @default.
• W4327733339 cites W2119007548 @default.
• W4327733339 cites W2121078745 @default.
• W4327733339 cites W2125038885 @default.
• W4327733339 cites W2129724822 @default.
• W4327733339 cites W2137831174 @default.
• W4327733339 cites W2162540156 @default.
• W4327733339 cites W2194478316 @default.
• W4327733339 cites W2214791309 @default.
• W4327733339 cites W2258318060 @default.
• W4327733339 cites W2332521027 @default.
• W4327733339 cites W2475905303 @default.
• W4327733339 cites W2524754702 @default.
• W4327733339 cites W2529373149 @default.
• W4327733339 cites W2534733910 @default.
• W4327733339 cites W2536389448 @default.
• W4327733339 cites W2552370831 @default.
• W4327733339 cites W2560367415 @default.
• W4327733339 cites W2560827811 @default.
• W4327733339 cites W2572623634 @default.
• W4327733339 cites W2600778287 @default.
• W4327733339 cites W2604320765 @default.
• W4327733339 cites W2611090362 @default.
• W4327733339 cites W2616761213 @default.
• W4327733339 cites W2624599834 @default.
• W4327733339 cites W2630819634 @default.
• W4327733339 cites W2732109088 @default.
• W4327733339 cites W2738442926 @default.
• W4327733339 cites W2741790433 @default.
• W4327733339 cites W2744849445 @default.
• W4327733339 cites W2761388963 @default.
• W4327733339 cites W2766581537 @default.
• W4327733339 cites W2767250022 @default.
• W4327733339 cites W2782390899 @default.
• W4327733339 cites W2788935695 @default.
• W4327733339 cites W2795875131 @default.
• W4327733339 cites W2799443762 @default.
• W4327733339 cites W2832528908 @default.
• W4327733339 cites W2849106131 @default.
• W4327733339 cites W2883452044 @default.
• W4327733339 cites W2886414470 @default.
• W4327733339 cites W2888408613 @default.
• W4327733339 cites W2889646458 @default.
• W4327733339 cites W2909404813 @default.
• W4327733339 cites W2915045264 @default.
• W4327733339 cites W2921642542 @default.
• W4327733339 cites W2928481113 @default.
• W4327733339 cites W2936562705 @default.
• W4327733339 cites W2942432629 @default.
• W4327733339 cites W2944420683 @default.
• W4327733339 cites W2950520897 @default.
• W4327733339 cites W2978521015 @default.
• W4327733339 cites W2979970262 @default.
• W4327733339 cites W2989662408 @default.
• W4327733339 cites W2990386639 @default.
• W4327733339 cites W3011361209 @default.
• W4327733339 cites W3015123349 @default.
• W4327733339 cites W3021719484 @default.
• W4327733339 cites W3022155705 @default.
• W4327733339 cites W3026726498 @default.
• W4327733339 cites W3037115677 @default.
• W4327733339 cites W3039084246 @default.
• W4327733339 cites W3047020306 @default.
• W4327733339 cites W3048165201 @default.
• W4327733339 cites W3084155739 @default.
• W4327733339 cites W3087480623 @default.
• W4327733339 cites W3107627756 @default.
• W4327733339 cites W3124581135 @default.
• W4327733339 cites W3128471106 @default.

• next