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- W4327737557 abstract "Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. Immune checkpoint inhibitors (ICIs) have become the new reference standard in first-line HCC treatment, replacing tyrosine kinase inhibitors (TKIs) such as sorafenib. Many clinical trials with different combinations are already in development to validate novel immunotherapies for the treatment of patients with HCC. Adoptive cell therapy (ACT), also known as cellular immunotherapy, with chimeric antigen receptors (CAR) or gene-modified T cells expressing novel T cell receptors (TCR) may represent a promising alternative approach to modify the immune system to recognize tumor cells with better clinical outcomes. In this review, we briefly discuss the overview of ACT as a promising treatment modality in HCC, along with recent updates of ongoing clinical trials." @default.
- W4327737557 created "2023-03-18" @default.
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- W4327737557 date "2023-03-16" @default.
- W4327737557 modified "2023-10-17" @default.
- W4327737557 title "Adoptive Cell Therapy in Hepatocellular Carcinoma: A Review of Clinical Trials" @default.
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- W4327737557 doi "https://doi.org/10.3390/cancers15061808" @default.
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