FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4327811326> ?p ?o ?g. }

• W4327811326 abstract "Abstract Chemotherapeutics can induce immunogenic cell death (ICD) by triggering autophagy and mediate antitumor immunotherapy. However, using chemotherapeutics alone can only cause mild cell‐protective autophagy and be incapable of inducing sufficient ICD efficacy. The participation of autophagy inducer is competent to enhance autophagy, so the level of ICD is promoted and the effect of antitumor immunotherapy is highly increased. Herein, tailor‐made autophagy cascade amplification polymeric nanoparticles STF@AHPPE are constructed to enhance tumor immunotherapy. Arginine (Arg), polyethyleneglycol–polycaprolactone, and epirubicin (EPI) are grafted onto hyaluronic acid (HA) via disulfide bond to form the AHPPE nanoparticles and autophagy inducer STF‐62247 (STF) is loaded. When STF@AHPPE nanoparticles target to tumor tissues and efficiently enter into tumor cells with the help of HA and Arg, the high glutathione concentration leads to the cleavage of disulfide bond and the release of EPI and STF. Finally, STF@AHPPE induces violent cytotoxic autophagy and strong ICD efficacy. As compared to AHPPE nanoparticles, STF@AHPPE nanoparticles kill the most tumor cells and show the more obvious ICD efficacy and immune activation ability. This work provides a novel strategy for combining tumor chemo‐immunotherapy with autophagy induction." @default.
• W4327811326 created "2023-03-19" @default.
• W4327811326 creator A5002992643 @default.
• W4327811326 creator A5012313693 @default.
• W4327811326 creator A5023153444 @default.
• W4327811326 creator A5023714240 @default.
• W4327811326 creator A5043200545 @default.
• W4327811326 creator A5060342278 @default.
• W4327811326 creator A5062951736 @default.
• W4327811326 creator A5065643681 @default.
• W4327811326 creator A5076930022 @default.
• W4327811326 creator A5080885767 @default.
• W4327811326 date "2023-03-18" @default.
• W4327811326 modified "2023-10-12" @default.
• W4327811326 title "Tailor‐Made Autophagy Cascade Amplification Polymeric Nanoparticles for Enhanced Tumor Immunotherapy" @default.
• W4327811326 cites W1192952131 @default.
• W4327811326 cites W1779771004 @default.
• W4327811326 cites W1968866426 @default.
• W4327811326 cites W1989195046 @default.
• W4327811326 cites W2047902191 @default.
• W4327811326 cites W2103596198 @default.
• W4327811326 cites W2106972520 @default.
• W4327811326 cites W2120426523 @default.
• W4327811326 cites W2128537698 @default.
• W4327811326 cites W2470720950 @default.
• W4327811326 cites W2471277546 @default.
• W4327811326 cites W2481327576 @default.
• W4327811326 cites W2514076633 @default.
• W4327811326 cites W2536322725 @default.
• W4327811326 cites W2554773181 @default.
• W4327811326 cites W2620637657 @default.
• W4327811326 cites W2685284983 @default.
• W4327811326 cites W2736538915 @default.
• W4327811326 cites W2762678799 @default.
• W4327811326 cites W2788640168 @default.
• W4327811326 cites W2803132938 @default.
• W4327811326 cites W2883585537 @default.
• W4327811326 cites W2886471216 @default.
• W4327811326 cites W2897570149 @default.
• W4327811326 cites W2905449398 @default.
• W4327811326 cites W2909301717 @default.
• W4327811326 cites W2920648489 @default.
• W4327811326 cites W2935430861 @default.
• W4327811326 cites W2940844078 @default.
• W4327811326 cites W2960083489 @default.
• W4327811326 cites W2980389798 @default.
• W4327811326 cites W2993090100 @default.
• W4327811326 cites W3002496002 @default.
• W4327811326 cites W3037121839 @default.
• W4327811326 cites W3048260089 @default.
• W4327811326 cites W3087167818 @default.
• W4327811326 cites W3109841970 @default.
• W4327811326 cites W3128646645 @default.
• W4327811326 cites W3134549127 @default.
• W4327811326 cites W3164159138 @default.
• W4327811326 cites W3178455983 @default.
• W4327811326 cites W4200310335 @default.
• W4327811326 cites W4214492787 @default.
• W4327811326 cites W4295364795 @default.
• W4327811326 doi "https://doi.org/10.1002/smll.202207898" @default.
• W4327811326 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36932938" @default.
• W4327811326 hasPublicationYear "2023" @default.
• W4327811326 type Work @default.
• W4327811326 citedByCount "3" @default.
• W4327811326 countsByYear W43278113262023 @default.
• W4327811326 crossrefType "journal-article" @default.
• W4327811326 hasAuthorship W4327811326A5002992643 @default.
• W4327811326 hasAuthorship W4327811326A5012313693 @default.
• W4327811326 hasAuthorship W4327811326A5023153444 @default.
• W4327811326 hasAuthorship W4327811326A5023714240 @default.
• W4327811326 hasAuthorship W4327811326A5043200545 @default.
• W4327811326 hasAuthorship W4327811326A5060342278 @default.
• W4327811326 hasAuthorship W4327811326A5062951736 @default.
• W4327811326 hasAuthorship W4327811326A5065643681 @default.
• W4327811326 hasAuthorship W4327811326A5076930022 @default.
• W4327811326 hasAuthorship W4327811326A5080885767 @default.
• W4327811326 hasConcept C185592680 @default.
• W4327811326 hasConcept C190283241 @default.
• W4327811326 hasConcept C192562407 @default.
• W4327811326 hasConcept C203014093 @default.
• W4327811326 hasConcept C203522944 @default.
• W4327811326 hasConcept C2777701055 @default.
• W4327811326 hasConcept C2777877232 @default.
• W4327811326 hasConcept C502942594 @default.
• W4327811326 hasConcept C55493867 @default.
• W4327811326 hasConcept C86803240 @default.
• W4327811326 hasConcept C8891405 @default.
• W4327811326 hasConceptScore W4327811326C185592680 @default.
• W4327811326 hasConceptScore W4327811326C190283241 @default.
• W4327811326 hasConceptScore W4327811326C192562407 @default.
• W4327811326 hasConceptScore W4327811326C203014093 @default.
• W4327811326 hasConceptScore W4327811326C203522944 @default.
• W4327811326 hasConceptScore W4327811326C2777701055 @default.
• W4327811326 hasConceptScore W4327811326C2777877232 @default.
• W4327811326 hasConceptScore W4327811326C502942594 @default.
• W4327811326 hasConceptScore W4327811326C55493867 @default.
• W4327811326 hasConceptScore W4327811326C86803240 @default.
• W4327811326 hasConceptScore W4327811326C8891405 @default.
• W4327811326 hasFunder F4320321001 @default.
• W4327811326 hasFunder F4320321543 @default.

• next