Matches in SemOpenAlex for { <https://semopenalex.org/work/W4327898098> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W4327898098 endingPage "369" @default.
- W4327898098 startingPage "363" @default.
- W4327898098 abstract "Introduction The determination of recent cannabis use is of forensic interest in the investigation of automotive crashes, workplace incidents and other mishaps. Because Δ9-tetrahydrocannabinol may persist in blood after psychoactive effects of intoxication resolve, particularly in regular users, short-lived minor cannabinoids such as cannabigerol have merited examination as adjunct indicators of recent cannabis inhalation.Methods As part of an observational cohort study, whole blood cannabinoids including cannabigerol were measured in whole blood by liquid chromatography with tandem mass spectrometry at baseline, and 30 minutes after initiation of a 15-minute supervised interval of ad libitum cannabis smoking in occasional (1–2 days/week over the past 30 days) (n = 24) and daily cannabis smokers (n = 32). Per protocol, subjects self-reported abstention from inhaling cannabis (>8 h) or ingesting cannabis (>12 h) prior to baseline measurement.Results At baseline, none of the occasional users had detectable cannabigerol (limit of detection = 0.2 µg/L), whereas cannabigerol was detectable post-smoking in 7 of 24 (29%). Among daily cannabis users, 2 of 32 (6%) had detectable cannabigerol at baseline, increasing to 21 of 32 (66%) post-smoking. The odds ratio for recent cannabis smoking associated with a detectable cannabigerol was 27 (95% confidence interval: 6.6, 110.3). In this mixed cohort of occasional and daily cannabis users, receiver operator characteristic curve analysis indicated that whole blood cannabigerol concentration of ≥ 0.2 µg/L had 96% specificity, 50% sensitivity, and 73% accuracy for identifying a 15-minute interval of ad libitum cannabis smoking initiated 30 minutes earlier. Post smoking blood Δ9-tetrahydrocannabinol (median = 5.6 µg/L in occasional users, 21.3 µg/L in daily users) was significantly correlated with post-smoking cannabigerol (P < 0.0001).Conclusion Whole blood cannabigerol may have forensic utility as a highly specific albeit insensitive biomarker of recent cannabis smoking." @default.
- W4327898098 created "2023-03-21" @default.
- W4327898098 creator A5006176105 @default.
- W4327898098 creator A5006400188 @default.
- W4327898098 creator A5008447148 @default.
- W4327898098 creator A5011573701 @default.
- W4327898098 creator A5021153178 @default.
- W4327898098 creator A5027398009 @default.
- W4327898098 creator A5028506802 @default.
- W4327898098 creator A5064282421 @default.
- W4327898098 date "2023-03-20" @default.
- W4327898098 modified "2023-10-16" @default.
- W4327898098 title "The minor cannabinoid cannabigerol (CBG) is a highly specific blood biomarker of recent cannabis smoking" @default.
- W4327898098 cites W18538872 @default.
- W4327898098 cites W1979341533 @default.
- W4327898098 cites W2027835625 @default.
- W4327898098 cites W2061737468 @default.
- W4327898098 cites W2125131025 @default.
- W4327898098 cites W2201370322 @default.
- W4327898098 cites W2531420938 @default.
- W4327898098 cites W2599685769 @default.
- W4327898098 cites W2743122121 @default.
- W4327898098 cites W2902194821 @default.
- W4327898098 cites W2912238467 @default.
- W4327898098 cites W3038325336 @default.
- W4327898098 cites W3101760808 @default.
- W4327898098 cites W3121363966 @default.
- W4327898098 cites W3172416309 @default.
- W4327898098 cites W3193564666 @default.
- W4327898098 cites W3215204882 @default.
- W4327898098 cites W4285795604 @default.
- W4327898098 doi "https://doi.org/10.1080/15563650.2023.2173076" @default.
- W4327898098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36939145" @default.
- W4327898098 hasPublicationYear "2023" @default.
- W4327898098 type Work @default.
- W4327898098 citedByCount "1" @default.
- W4327898098 countsByYear W43278980982023 @default.
- W4327898098 crossrefType "journal-article" @default.
- W4327898098 hasAuthorship W4327898098A5006176105 @default.
- W4327898098 hasAuthorship W4327898098A5006400188 @default.
- W4327898098 hasAuthorship W4327898098A5008447148 @default.
- W4327898098 hasAuthorship W4327898098A5011573701 @default.
- W4327898098 hasAuthorship W4327898098A5021153178 @default.
- W4327898098 hasAuthorship W4327898098A5027398009 @default.
- W4327898098 hasAuthorship W4327898098A5028506802 @default.
- W4327898098 hasAuthorship W4327898098A5064282421 @default.
- W4327898098 hasConcept C118552586 @default.
- W4327898098 hasConcept C126322002 @default.
- W4327898098 hasConcept C156957248 @default.
- W4327898098 hasConcept C170493617 @default.
- W4327898098 hasConcept C201903717 @default.
- W4327898098 hasConcept C2777056318 @default.
- W4327898098 hasConcept C2780871563 @default.
- W4327898098 hasConcept C2908858883 @default.
- W4327898098 hasConcept C44249647 @default.
- W4327898098 hasConcept C71924100 @default.
- W4327898098 hasConcept C72563966 @default.
- W4327898098 hasConceptScore W4327898098C118552586 @default.
- W4327898098 hasConceptScore W4327898098C126322002 @default.
- W4327898098 hasConceptScore W4327898098C156957248 @default.
- W4327898098 hasConceptScore W4327898098C170493617 @default.
- W4327898098 hasConceptScore W4327898098C201903717 @default.
- W4327898098 hasConceptScore W4327898098C2777056318 @default.
- W4327898098 hasConceptScore W4327898098C2780871563 @default.
- W4327898098 hasConceptScore W4327898098C2908858883 @default.
- W4327898098 hasConceptScore W4327898098C44249647 @default.
- W4327898098 hasConceptScore W4327898098C71924100 @default.
- W4327898098 hasConceptScore W4327898098C72563966 @default.
- W4327898098 hasIssue "5" @default.
- W4327898098 hasLocation W43278980981 @default.
- W4327898098 hasLocation W43278980982 @default.
- W4327898098 hasOpenAccess W4327898098 @default.
- W4327898098 hasPrimaryLocation W43278980981 @default.
- W4327898098 hasRelatedWork W1516627712 @default.
- W4327898098 hasRelatedWork W1972435539 @default.
- W4327898098 hasRelatedWork W2002222675 @default.
- W4327898098 hasRelatedWork W2321655004 @default.
- W4327898098 hasRelatedWork W2766450508 @default.
- W4327898098 hasRelatedWork W2986406350 @default.
- W4327898098 hasRelatedWork W3147048938 @default.
- W4327898098 hasRelatedWork W3161107174 @default.
- W4327898098 hasRelatedWork W349906426 @default.
- W4327898098 hasRelatedWork W4210771126 @default.
- W4327898098 hasVolume "61" @default.
- W4327898098 isParatext "false" @default.
- W4327898098 isRetracted "false" @default.
- W4327898098 workType "article" @default.