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• W4327918817 endingPage "100758" @default.
• W4327918817 startingPage "100758" @default.
• W4327918817 abstract "Hereditary angioedema (HAE) is a rare disorder that causes unpredictable and debilitating cutaneous and submucosal edema and can lead to death. HAE can impair patients' ability to perform daily activities, proportional to pain severity, with patients reporting lower productivity, missed time from work or school and potentially resulting in missed career and educational opportunities. Many patients with HAE experience a significant psychological burden, including anxiety and depression. Available treatment aims to prevent and/or treat HAE attacks as they occur, to reduce morbidity and mortality and, finally, to improve health-related quality of life. Two different validated specific angioedema instruments are available to assess patients' quality of life. The Angioedema Quality of Life Questionnaire (AE-QoL) examines diagnosed patients' quality of life but is not specific for HAE. The disease-specific questionnaire is the Hereditary Angioedema Quality of Life (HAE-QoL), and the first used for hereditary angioedema with C1 inhibitors (C1-INH) deficiency. These quality-of-life instruments are helpful to the HAE patients' assessment and to the development of better therapeutic strategies as clinical tools, as defined by international guidelines. Considering this context, this review was conducted to compare the effects of acute vs. long-term prophylaxis on HAE patients' health-related quality of life. In addition, the prevalence of anxiety and depression among these individuals was also reviewed." @default.
• W4327918817 created "2023-03-21" @default.
• W4327918817 creator A5053275824 @default.
• W4327918817 date "2023-03-01" @default.
• W4327918817 modified "2023-10-01" @default.
• W4327918817 title "A narrative review of recent literature of the quality of life in hereditary angioedema patients" @default.
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• W4327918817 doi "https://doi.org/10.1016/j.waojou.2023.100758" @default.
• W4327918817 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36994443" @default.
• W4327918817 hasPublicationYear "2023" @default.
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