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- W4327920774 abstract "Herein, we developed the palladium-catalyzed Sonogashira-type cross-coupling of 1‑bromo-2,2-difluoroethylene with a variety of aromatic and aliphatic terminal alkynes proceeds smoothly at mild reaction condition to access the corresponding gem‑difluoroenyne derivatives. 1-Bromo-2,2-difluoroethylene is a useful difluoroethenyl source because of its commercially available and easy-to-handle. This new synthetic protocol provided a novel strategy to directly construct gem‑difluoroenynes with good functional group tolerance and high yields." @default.
- W4327920774 created "2023-03-21" @default.
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- W4327920774 date "2023-05-01" @default.
- W4327920774 modified "2023-10-10" @default.
- W4327920774 title "Palladium-catalyzed Sonogashira coupling to synthesis of gem‑difluoroenynes" @default.
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- W4327920774 doi "https://doi.org/10.1016/j.jfluchem.2023.110111" @default.
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