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- W4327932017 abstract "Introduction Lupus anticoagulans is the most important factor in the detection of antiphospholipid syndrome (APS). APS is a hypercoagulable state accompanied by the presence of heterogeneous antiphospholipid antibodies (aPL) that nonspecifically affect hemostasis. The effect is due to their binding to phospholipid surfaces, thereby prolonging screening coagulation tests such as aPTT, but this does not correlate with the incidence of thrombotic complications in APS. This situation is clarified by the theory that the main target of antibodies is the activated protein C (APC) system, the elimination of which may manifest as thrombotic complications." @default.
- W4327932017 created "2023-03-21" @default.
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- W4327932017 date "2023-02-01" @default.
- W4327932017 modified "2023-10-17" @default.
- W4327932017 title "Can APC inhibition by lupus anticoagulants indicate antibody thrombogenicity?" @default.
- W4327932017 doi "https://doi.org/10.1055/s-0042-1760498" @default.
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