Matches in SemOpenAlex for { <https://semopenalex.org/work/W4327932022> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W4327932022 abstract "Introduction In the liver vasculature the oxygenated arterial and nutrient rich portal venous blood mix within the sinusoidal space that drains into a hypoxic central vein. These sinusoids are lined with liver sinusoidal endothelial cells (LSEC) which are unique endothelial cells. They have a variety of important functions and one of them is secretion and expression of FVIII. Pluripotent stem cells from healthy donors can be a source of generating organ specific endothelial cells in vitro. However, maintaining the specification and expression of LSEC markers (F8) remains a challenge. Currently, embryoid bodies with a combination of adrenomedullin pathway activation, TGF-ß inhibition and hypoxia are a state of the art to derive LSEC-like EC from IPS. A 2D monolayer-based approach established by our group can not only increase the proliferative potential of these endothelial cells but also help in maintaining their specification." @default.
- W4327932022 created "2023-03-21" @default.
- W4327932022 creator A5066422670 @default.
- W4327932022 creator A5077755552 @default.
- W4327932022 creator A5079861916 @default.
- W4327932022 creator A5079956403 @default.
- W4327932022 date "2023-02-01" @default.
- W4327932022 modified "2023-10-10" @default.
- W4327932022 title "Establishment and specification analysis of LSEC-like endothelial cells for the detection of endogenous FVIII" @default.
- W4327932022 cites W1563180177 @default.
- W4327932022 cites W1591152393 @default.
- W4327932022 cites W1997760245 @default.
- W4327932022 cites W2126698695 @default.
- W4327932022 cites W2128487729 @default.
- W4327932022 cites W2187048772 @default.
- W4327932022 cites W3038630761 @default.
- W4327932022 cites W4223460229 @default.
- W4327932022 doi "https://doi.org/10.1055/s-0042-1760541" @default.
- W4327932022 hasPublicationYear "2023" @default.
- W4327932022 type Work @default.
- W4327932022 citedByCount "0" @default.
- W4327932022 crossrefType "proceedings-article" @default.
- W4327932022 hasAuthorship W4327932022A5066422670 @default.
- W4327932022 hasAuthorship W4327932022A5077755552 @default.
- W4327932022 hasAuthorship W4327932022A5079861916 @default.
- W4327932022 hasAuthorship W4327932022A5079956403 @default.
- W4327932022 hasConcept C104317684 @default.
- W4327932022 hasConcept C107459253 @default.
- W4327932022 hasConcept C123012128 @default.
- W4327932022 hasConcept C134018914 @default.
- W4327932022 hasConcept C143948831 @default.
- W4327932022 hasConcept C145103041 @default.
- W4327932022 hasConcept C201750760 @default.
- W4327932022 hasConcept C202751555 @default.
- W4327932022 hasConcept C203014093 @default.
- W4327932022 hasConcept C20875687 @default.
- W4327932022 hasConcept C2776992346 @default.
- W4327932022 hasConcept C28328180 @default.
- W4327932022 hasConcept C55493867 @default.
- W4327932022 hasConcept C60781801 @default.
- W4327932022 hasConcept C86803240 @default.
- W4327932022 hasConcept C95444343 @default.
- W4327932022 hasConceptScore W4327932022C104317684 @default.
- W4327932022 hasConceptScore W4327932022C107459253 @default.
- W4327932022 hasConceptScore W4327932022C123012128 @default.
- W4327932022 hasConceptScore W4327932022C134018914 @default.
- W4327932022 hasConceptScore W4327932022C143948831 @default.
- W4327932022 hasConceptScore W4327932022C145103041 @default.
- W4327932022 hasConceptScore W4327932022C201750760 @default.
- W4327932022 hasConceptScore W4327932022C202751555 @default.
- W4327932022 hasConceptScore W4327932022C203014093 @default.
- W4327932022 hasConceptScore W4327932022C20875687 @default.
- W4327932022 hasConceptScore W4327932022C2776992346 @default.
- W4327932022 hasConceptScore W4327932022C28328180 @default.
- W4327932022 hasConceptScore W4327932022C55493867 @default.
- W4327932022 hasConceptScore W4327932022C60781801 @default.
- W4327932022 hasConceptScore W4327932022C86803240 @default.
- W4327932022 hasConceptScore W4327932022C95444343 @default.
- W4327932022 hasLocation W43279320221 @default.
- W4327932022 hasOpenAccess W4327932022 @default.
- W4327932022 hasPrimaryLocation W43279320221 @default.
- W4327932022 hasRelatedWork W1546395618 @default.
- W4327932022 hasRelatedWork W2076733365 @default.
- W4327932022 hasRelatedWork W2112832471 @default.
- W4327932022 hasRelatedWork W2547210335 @default.
- W4327932022 hasRelatedWork W2560446420 @default.
- W4327932022 hasRelatedWork W2597105089 @default.
- W4327932022 hasRelatedWork W2855144615 @default.
- W4327932022 hasRelatedWork W3143039084 @default.
- W4327932022 hasRelatedWork W3153655660 @default.
- W4327932022 hasRelatedWork W4309020965 @default.
- W4327932022 isParatext "false" @default.
- W4327932022 isRetracted "false" @default.
- W4327932022 workType "article" @default.