FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4327979591> ?p ?o ?g. }

• W4327979591 abstract "Low-volume lung injury encompasses local concentration of stresses in the vicinity of collapsed regions in heterogeneously ventilated lungs. We aimed to study the effects on ventilation and perfusion distributions of a sequential lateral positioning (30°) strategy using electrical impedance tomography imaging in a porcine experimental model of early acute respiratory distress syndrome (ARDS). We hypothesized that such strategy, including a real-time individualization of positive end-expiratory pressure (PEEP) whenever in lateral positioning, would provide attenuation of collapse in the dependent lung regions. A two-hit injury acute respiratory distress syndrome experimental model was established by lung lavages followed by injurious mechanical ventilation. Then, all animals were studied in five body positions in a sequential order, 15 min each: Supine 1; Lateral Left; Supine 2; Lateral Right; Supine 3. The following functional images were analyzed by electrical impedance tomography: ventilation distributions and regional lung volumes, and perfusion distributions. The induction of the acute respiratory distress syndrome model resulted in a marked fall in oxygenation along with low regional ventilation and compliance of the dorsal half of the lung (gravitational-dependent in supine position). Both the regional ventilation and compliance of the dorsal half of the lung greatly increased along of the sequential lateral positioning strategy, and maximally at its end. In addition, a corresponding improvement of oxygenation occurred. In conclusion, our sequential lateral positioning strategy, with sufficient positive end-expiratory pressure to prevent collapse of the dependent lung units during lateral positioning, provided a relevant diminution of collapse in the dorsal lung in a porcine experimental model of early acute respiratory distress syndrome." @default.
• W4327979591 created "2023-03-21" @default.
• W4327979591 creator A5004513909 @default.
• W4327979591 creator A5021911390 @default.
• W4327979591 creator A5025872628 @default.
• W4327979591 creator A5040826667 @default.
• W4327979591 creator A5043824744 @default.
• W4327979591 creator A5046807666 @default.
• W4327979591 creator A5049304644 @default.
• W4327979591 creator A5066477833 @default.
• W4327979591 creator A5075318238 @default.
• W4327979591 date "2023-03-20" @default.
• W4327979591 modified "2023-09-26" @default.
• W4327979591 title "Real-time effects of lateral positioning on regional ventilation and perfusion in an experimental model of acute respiratory distress syndrome" @default.
• W4327979591 cites W1638587052 @default.
• W4327979591 cites W1823772832 @default.
• W4327979591 cites W1868307336 @default.
• W4327979591 cites W1944705852 @default.
• W4327979591 cites W1972372634 @default.
• W4327979591 cites W1973686267 @default.
• W4327979591 cites W1976636356 @default.
• W4327979591 cites W2009478257 @default.
• W4327979591 cites W2021449497 @default.
• W4327979591 cites W2036409944 @default.
• W4327979591 cites W2054972605 @default.
• W4327979591 cites W2066418491 @default.
• W4327979591 cites W2068854215 @default.
• W4327979591 cites W2077956220 @default.
• W4327979591 cites W2084245756 @default.
• W4327979591 cites W2092002774 @default.
• W4327979591 cites W2117843079 @default.
• W4327979591 cites W2119517702 @default.
• W4327979591 cites W2120034179 @default.
• W4327979591 cites W2120271827 @default.
• W4327979591 cites W2120371872 @default.
• W4327979591 cites W2125766343 @default.
• W4327979591 cites W2135955684 @default.
• W4327979591 cites W2136420364 @default.
• W4327979591 cites W2152554877 @default.
• W4327979591 cites W2155235791 @default.
• W4327979591 cites W2167743972 @default.
• W4327979591 cites W2175468597 @default.
• W4327979591 cites W2199272818 @default.
• W4327979591 cites W2272081540 @default.
• W4327979591 cites W2286228001 @default.
• W4327979591 cites W2399761172 @default.
• W4327979591 cites W2413004034 @default.
• W4327979591 cites W2620241325 @default.
• W4327979591 cites W2898288076 @default.
• W4327979591 cites W2978793344 @default.
• W4327979591 cites W3003753225 @default.
• W4327979591 cites W3037900702 @default.
• W4327979591 cites W3043123684 @default.
• W4327979591 cites W3081209224 @default.
• W4327979591 cites W3120975401 @default.
• W4327979591 cites W3124838846 @default.
• W4327979591 cites W3156624684 @default.
• W4327979591 cites W4210990743 @default.
• W4327979591 cites W2121123540 @default.
• W4327979591 cites W2411270044 @default.
• W4327979591 cites W3094365463 @default.
• W4327979591 doi "https://doi.org/10.3389/fphys.2023.1113568" @default.
• W4327979591 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37020459" @default.
• W4327979591 hasPublicationYear "2023" @default.
• W4327979591 type Work @default.
• W4327979591 citedByCount "0" @default.
• W4327979591 crossrefType "journal-article" @default.
• W4327979591 hasAuthorship W4327979591A5004513909 @default.
• W4327979591 hasAuthorship W4327979591A5021911390 @default.
• W4327979591 hasAuthorship W4327979591A5025872628 @default.
• W4327979591 hasAuthorship W4327979591A5040826667 @default.
• W4327979591 hasAuthorship W4327979591A5043824744 @default.
• W4327979591 hasAuthorship W4327979591A5046807666 @default.
• W4327979591 hasAuthorship W4327979591A5049304644 @default.
• W4327979591 hasAuthorship W4327979591A5066477833 @default.
• W4327979591 hasAuthorship W4327979591A5075318238 @default.
• W4327979591 hasBestOaLocation W43279795911 @default.
• W4327979591 hasConcept C105702510 @default.
• W4327979591 hasConcept C121332964 @default.
• W4327979591 hasConcept C125567185 @default.
• W4327979591 hasConcept C126322002 @default.
• W4327979591 hasConcept C136936797 @default.
• W4327979591 hasConcept C141983124 @default.
• W4327979591 hasConcept C146957229 @default.
• W4327979591 hasConcept C163100246 @default.
• W4327979591 hasConcept C164705383 @default.
• W4327979591 hasConcept C200457457 @default.
• W4327979591 hasConcept C27101514 @default.
• W4327979591 hasConcept C2776348555 @default.
• W4327979591 hasConcept C2777080012 @default.
• W4327979591 hasConcept C2777257755 @default.
• W4327979591 hasConcept C2777714996 @default.
• W4327979591 hasConcept C42219234 @default.
• W4327979591 hasConcept C534529494 @default.
• W4327979591 hasConcept C70289976 @default.
• W4327979591 hasConcept C71924100 @default.
• W4327979591 hasConcept C97355855 @default.
• W4327979591 hasConceptScore W4327979591C105702510 @default.
• W4327979591 hasConceptScore W4327979591C121332964 @default.
• W4327979591 hasConceptScore W4327979591C125567185 @default.

• next