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- W4328013141 abstract "ObjectiveTo evaluate the relation between rs619586 metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) gene single nucleotide polymorphism (SNP) and hepatocellular carcinoma (HCC) risk on top of hepatitis C virus (HCV).BackgroundHCC is a type of primary liver cancer. It has a multitude of etiological risk factors such as HCV. The MALAT1 is a long noncoding RNA. It affects tumor cell proliferation and migration in many types of malignancy.Patients and methodsThe study included 80 subjects: 40 patients with HCC on top of HCV and 40 healthy controls. Genotyping of MALAT1 SNP (rs619586) was performed by real-time PCR.ResultsThere were no significant statistical differences regarding the genotypes or allele distribution of MALAT1 SNP (rs619586) on comparing HCC on top of HCV with controls.ConclusionThis study found that there was no significant statistical difference regarding the genotypes or allele distribution of MALAT1 SNP (rs619586) on comparing HCC on top of HCV with controls." @default.
- W4328013141 created "2023-03-22" @default.
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- W4328013141 date "2022-01-01" @default.
- W4328013141 modified "2023-09-25" @default.
- W4328013141 title "Metastasis-associated lung adenocarcinoma transcript 1 gene polymorphism in Egyptian patients with hepatocellular carcinoma" @default.
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- W4328013141 doi "https://doi.org/10.4103/mmj.mmj_200_22" @default.
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