FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328030004> ?p ?o ?g. }

• W4328030004 endingPage "52" @default.
• W4328030004 startingPage "46" @default.
• W4328030004 abstract "On the basis of periodontal indices, the anti-plaque and anti-inflammatory effect of the gel composition of the new domestic drug, the main active ingredient of which is dihydroquercetin contained in the bark of Siberian larch, which has an antioxidant and antihypoxant effect, was studied. From practically healthy patients aged 18 to 40 years with inflammatory changes in the marginal periodontium (with chronic catarrhal gingivitis and mild periodontitis) without serious concomitant diseases, 2 groups were formed — control (group A) and experience (group B), 30 people in each group. Patients were not separated by gender. At the first stage, patients were taught the rules of brushing their teeth and hygienic care of the oral cavity using demonstration phantoms. Then, after antiseptic treatment of the marginal periodontium and application anesthesia, dental deposits were removed for patients of both groups. At this point, treatment intervention for patients in the control group (Group B) was limited. Patients of group A were additionally prescribed applications of a therapeutic gel. Patients applied the drug to the gums previously dried with a cotton swab from the outer and inner surfaces on their own with a frequency of 3 times a day after demonstrating the rules for the procedure and monitoring by the specialist the correctness of its implementation by the patients themselves.&#x0D; The clinical condition of the soft tissues in patients of both groups was monitored before the start of treatment, after 3, 7 and 14 days based on a number of indices: Silness-Loe, PMA and Mulleman).&#x0D; The Muhleman Index values in patients before treatment in both groups were 2.4±0.5 and 2.3±0.5 c.u. (conventional unit)., respectively. In subsequent terms, after 3, 7 and 14 days, the index values progressively decreased. 3 days after the removal of dental deposits, the index values significantly decreased: to 1.7±0.5 c.u. in the first and up to 1.9±0.6 c.u. in the second (p<0.05) group of patients. After 7 days, the bleeding index progressively decreased also in both groups, but less intensively. Moreover, the index in patients in group A was 1.1±0.4 and in patients in group B 1.5±0.5 and 0.5±0.1 c.u. Most clearly, the difference in the effect manifested itself on the 14-th day: 0.5±0.3 units. in patients of group A and 1±0.5 c.u. in patients in group B (in all cases p<0,05). The dynamics of the RMA inflammation index turned out to be very comparable with the dynamics of the Muhleman index in patients of both groups.&#x0D; The initial training in the rules of brushing the teeth made it possible to achieve an ideal cleansing of the oral cavity in both groups of patients, and the achieved effect was maintained throughout the study period. This confirmed the decrease in the Silness-Loe plaque index to almost zero, despite the fact that before the start of the study its values were the same and reached almost the maximum value: 2,4 c.u. in patients. of both groups. Characteristically, after 3 days, the index value in patients in both groups decreased almost identically to a value of 0.8 c.u., and after 7 and 14 days — almost to zero.&#x0D; This fact allowed us to attribute the achieved anti-inflammatory effect not due to more thorough brushing of teeth during the experiment, but precisely due to the therapeutic effect of the applied gel.&#x0D; The presented numerical data of clinical indicators were confirmed by the results of statistical processing using the Student's method with the determination of the reliability criterion.&#x0D; Examination and questioning of patients made it possible to establish the absence of negative clinical and organoleptic sensations from the use of the gel in patients of both groups.&#x0D; The data obtained made it possible to establish a pronounced anti-inflammatory effect of the therapeutic gel Flamena stom. and to recommend the gel for use in wide clinical practice as part of the complex treatment of patients with inflammatory periodontal diseases." @default.
• W4328030004 created "2023-03-22" @default.
• W4328030004 creator A5013130605 @default.
• W4328030004 creator A5026907544 @default.
• W4328030004 creator A5066440740 @default.
• W4328030004 creator A5072584332 @default.
• W4328030004 date "2022-09-06" @default.
• W4328030004 modified "2023-10-16" @default.
• W4328030004 title "Clinical efficacy of the new dental gel based on dihydroquercetin in the treatment of patients with inflammatory periodontal diseases" @default.
• W4328030004 cites W3027510467 @default.
• W4328030004 cites W4210801852 @default.
• W4328030004 cites W4238465361 @default.
• W4328030004 cites W4239573811 @default.
• W4328030004 doi "https://doi.org/10.35556/idr-2022-3(100)46-52" @default.
• W4328030004 hasPublicationYear "2022" @default.
• W4328030004 type Work @default.
• W4328030004 citedByCount "0" @default.
• W4328030004 crossrefType "journal-article" @default.
• W4328030004 hasAuthorship W4328030004A5013130605 @default.
• W4328030004 hasAuthorship W4328030004A5026907544 @default.
• W4328030004 hasAuthorship W4328030004A5066440740 @default.
• W4328030004 hasAuthorship W4328030004A5072584332 @default.
• W4328030004 hasConcept C126322002 @default.
• W4328030004 hasConcept C142724271 @default.
• W4328030004 hasConcept C144374066 @default.
• W4328030004 hasConcept C199343813 @default.
• W4328030004 hasConcept C202271784 @default.
• W4328030004 hasConcept C2778380114 @default.
• W4328030004 hasConcept C2780035454 @default.
• W4328030004 hasConcept C2780385504 @default.
• W4328030004 hasConcept C2780641865 @default.
• W4328030004 hasConcept C2780791200 @default.
• W4328030004 hasConcept C2781460226 @default.
• W4328030004 hasConcept C71924100 @default.
• W4328030004 hasConcept C98274493 @default.
• W4328030004 hasConceptScore W4328030004C126322002 @default.
• W4328030004 hasConceptScore W4328030004C142724271 @default.
• W4328030004 hasConceptScore W4328030004C144374066 @default.
• W4328030004 hasConceptScore W4328030004C199343813 @default.
• W4328030004 hasConceptScore W4328030004C202271784 @default.
• W4328030004 hasConceptScore W4328030004C2778380114 @default.
• W4328030004 hasConceptScore W4328030004C2780035454 @default.
• W4328030004 hasConceptScore W4328030004C2780385504 @default.
• W4328030004 hasConceptScore W4328030004C2780641865 @default.
• W4328030004 hasConceptScore W4328030004C2780791200 @default.
• W4328030004 hasConceptScore W4328030004C2781460226 @default.
• W4328030004 hasConceptScore W4328030004C71924100 @default.
• W4328030004 hasConceptScore W4328030004C98274493 @default.
• W4328030004 hasIssue "3(100)" @default.
• W4328030004 hasLocation W43280300041 @default.
• W4328030004 hasOpenAccess W4328030004 @default.
• W4328030004 hasPrimaryLocation W43280300041 @default.
• W4328030004 hasRelatedWork W1526112813 @default.
• W4328030004 hasRelatedWork W3106804501 @default.
• W4328030004 hasRelatedWork W3137811436 @default.
• W4328030004 hasRelatedWork W3158637930 @default.
• W4328030004 hasRelatedWork W3173692466 @default.
• W4328030004 hasRelatedWork W3188057573 @default.
• W4328030004 hasRelatedWork W4254526117 @default.
• W4328030004 hasRelatedWork W4328030004 @default.
• W4328030004 hasRelatedWork W4328030005 @default.
• W4328030004 hasRelatedWork W3127968046 @default.
• W4328030004 isParatext "false" @default.
• W4328030004 isRetracted "false" @default.
• W4328030004 workType "article" @default.