Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328049051> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W4328049051 endingPage "2053" @default.
- W4328049051 startingPage "2050" @default.
- W4328049051 abstract "Scalp psoriasis frequently goes with other disease location and may lead to a significant burden and impairment of quality of life (QoL). Adherence to local treatments is a frequent problem. A keratolytic and hydrating shampoo containing 2% salicylic acid, 5% urea, and 1% glycerin (active shampoo) has been developed for psoriasis-prone scalp.To assess the efficacy and tolerability of an active shampoo in subjects with mild to moderate scalp psoriasis.A single-center, randomized, double-blind, vehicle-controlled study was conducted on 67 adults with mild to moderate psoriasis. The active shampoo or its vehicle were applied daily for 14 days and 3 times/week for another 14 days. Assessments included the Psoriasis Scalp Severity Index (PSSI), Investigator Global Assessment (IGA), calculated total surface affected hair, scalp greasiness, irritation, and assessed scalp dermatitis-specific quality-of-life issues using SCALPDEX and product acceptability.The active shampoo significantly (p < 0.05) reduced the PSSI by 39.0%, 37.2%, 63.0%, and 69.0% immediately after washing compared to a 22.8%, 5.5%, 19.6%, and 13.0% with the vehicle at Days 1, 8, 15, and 30, respectively. SCALPDEX items, IGA, and irritation significantly (p < 0.05) reduced with the active shampoo. Hair and scalp greasiness improved continuously with both products until Day 21. Subject-reported symptom scores paralleled the positive evolution of clinical signs. The active shampoo was well tolerated, subjects were highly satisfied and had an improved QoL.The active shampoo significantly improved clinical signs, symptoms, and QoL of mild-to-moderate scalp psoriasis compared to the vehicle. It was very well tolerated and highly appreciated by the subjects." @default.
- W4328049051 created "2023-03-22" @default.
- W4328049051 creator A5002265320 @default.
- W4328049051 creator A5003888665 @default.
- W4328049051 creator A5006007613 @default.
- W4328049051 creator A5009068053 @default.
- W4328049051 creator A5036259901 @default.
- W4328049051 creator A5037376216 @default.
- W4328049051 creator A5041180169 @default.
- W4328049051 creator A5045897295 @default.
- W4328049051 creator A5061697831 @default.
- W4328049051 creator A5061762229 @default.
- W4328049051 creator A5072724906 @default.
- W4328049051 date "2023-03-21" @default.
- W4328049051 modified "2023-10-18" @default.
- W4328049051 title "Clinical benefit and tolerance profile of a keratolytic and hydrating shampoo in subjects with mild to moderate psoriasis. Results from a double‐blind, randomized, vehicle‐controlled study" @default.
- W4328049051 cites W1977708900 @default.
- W4328049051 cites W1990128482 @default.
- W4328049051 cites W2011639154 @default.
- W4328049051 cites W2049961763 @default.
- W4328049051 cites W2063821107 @default.
- W4328049051 cites W2156148414 @default.
- W4328049051 cites W2733237180 @default.
- W4328049051 cites W3028355101 @default.
- W4328049051 doi "https://doi.org/10.1111/jocd.15693" @default.
- W4328049051 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36942745" @default.
- W4328049051 hasPublicationYear "2023" @default.
- W4328049051 type Work @default.
- W4328049051 citedByCount "0" @default.
- W4328049051 crossrefType "journal-article" @default.
- W4328049051 hasAuthorship W4328049051A5002265320 @default.
- W4328049051 hasAuthorship W4328049051A5003888665 @default.
- W4328049051 hasAuthorship W4328049051A5006007613 @default.
- W4328049051 hasAuthorship W4328049051A5009068053 @default.
- W4328049051 hasAuthorship W4328049051A5036259901 @default.
- W4328049051 hasAuthorship W4328049051A5037376216 @default.
- W4328049051 hasAuthorship W4328049051A5041180169 @default.
- W4328049051 hasAuthorship W4328049051A5045897295 @default.
- W4328049051 hasAuthorship W4328049051A5061697831 @default.
- W4328049051 hasAuthorship W4328049051A5061762229 @default.
- W4328049051 hasAuthorship W4328049051A5072724906 @default.
- W4328049051 hasBestOaLocation W43280490511 @default.
- W4328049051 hasConcept C126322002 @default.
- W4328049051 hasConcept C141071460 @default.
- W4328049051 hasConcept C142724271 @default.
- W4328049051 hasConcept C16005928 @default.
- W4328049051 hasConcept C168563851 @default.
- W4328049051 hasConcept C197934379 @default.
- W4328049051 hasConcept C203014093 @default.
- W4328049051 hasConcept C2777063393 @default.
- W4328049051 hasConcept C2778375690 @default.
- W4328049051 hasConcept C2778515351 @default.
- W4328049051 hasConcept C2780564577 @default.
- W4328049051 hasConcept C2781171460 @default.
- W4328049051 hasConcept C49735497 @default.
- W4328049051 hasConcept C71924100 @default.
- W4328049051 hasConceptScore W4328049051C126322002 @default.
- W4328049051 hasConceptScore W4328049051C141071460 @default.
- W4328049051 hasConceptScore W4328049051C142724271 @default.
- W4328049051 hasConceptScore W4328049051C16005928 @default.
- W4328049051 hasConceptScore W4328049051C168563851 @default.
- W4328049051 hasConceptScore W4328049051C197934379 @default.
- W4328049051 hasConceptScore W4328049051C203014093 @default.
- W4328049051 hasConceptScore W4328049051C2777063393 @default.
- W4328049051 hasConceptScore W4328049051C2778375690 @default.
- W4328049051 hasConceptScore W4328049051C2778515351 @default.
- W4328049051 hasConceptScore W4328049051C2780564577 @default.
- W4328049051 hasConceptScore W4328049051C2781171460 @default.
- W4328049051 hasConceptScore W4328049051C49735497 @default.
- W4328049051 hasConceptScore W4328049051C71924100 @default.
- W4328049051 hasIssue "7" @default.
- W4328049051 hasLocation W43280490511 @default.
- W4328049051 hasLocation W43280490512 @default.
- W4328049051 hasOpenAccess W4328049051 @default.
- W4328049051 hasPrimaryLocation W43280490511 @default.
- W4328049051 hasRelatedWork W152437768 @default.
- W4328049051 hasRelatedWork W1842168445 @default.
- W4328049051 hasRelatedWork W1966788665 @default.
- W4328049051 hasRelatedWork W1983875672 @default.
- W4328049051 hasRelatedWork W2793276621 @default.
- W4328049051 hasRelatedWork W3109629157 @default.
- W4328049051 hasRelatedWork W3214186490 @default.
- W4328049051 hasRelatedWork W4226239662 @default.
- W4328049051 hasRelatedWork W4308697821 @default.
- W4328049051 hasRelatedWork W58066341 @default.
- W4328049051 hasVolume "22" @default.
- W4328049051 isParatext "false" @default.
- W4328049051 isRetracted "false" @default.
- W4328049051 workType "article" @default.