FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328049352> ?p ?o ?g. }

• W4328049352 abstract "Type 1 diabetes mellitus (T1DM) patients are at an increased risk for non-alcoholic fatty liver disease (NAFLD). This study aimed to evaluate the clinical criteria associated with the diagnosis of Non-Alcoholic Fatty Liver Disease (NAFLD) among T1DM Egyptian children and adolescents.74 T1DM patients aged 8-18 year were enrolled in this cross sectional study. Assessments of Clinical status, anthropometric measures, lipid profile, glycated haemoglobin (HbA1c) and liver enzymes were done. Abdominal Ultrasound evaluation of hepatic steatosis was done. Accordingly, patients were divided into two groups (NAFLD and normal liver group) and compared together. Assessment of liver fibrosis using acoustic radiation force impulse elastography (ARFI) was done. Statistical analysis included; independent t-test, Chi square and Fisher's Exact, Pearson and Spearman tests and Logistic regression models for factors associated with fatty liver were used when appropriate.In this study; 74 patients were enrolled; 37 males (50%) and 37 females with mean age 14.3 ± 3.0 year. The mean insulin dose was 1.1 ± 0.4 U/kg and mean disease duration was 6.3 ± 3.0 year. NAFLD was detected in 46 cases while 28 cases had normal liver as diagnosed by abdominal ultrasound. Cases with NAFLD had statistically significant higher BMI-Z scores, waist/hip, waist/height and sum of skin fold thicknesses compared to those with normal liver (P < 0.05). The mean value of HbA1c % was significantly higher in NAFLD group (P = 0.003). Total cholesterol, triglycerides and LDL serum levels were significantly elevated (p < 0.05), while the HDL level was significantly lower in NAFLD cases (p = 0.001). Although, serum levels of liver enzymes; ALT and AST were significantly higher among cases with NAFLD than in normal liver group (p < 0.05), their means were within normal. Using the ARFI elastography; NAFLD cases exhibited significant fibrosis (F2, 3 and 4). BMI, patient age and female gender were among risk factors for NAFLD.NAFLD represents a serious consequence in type 1 diabetic children and adolescents that deserves attention especially with poor glycemic control. NAFLD has the potential to evolve to fibrosis. This study demonstrated a very high prevalence of NAFLD in T1D children and adolescents using US which was (62.2%) with the percent of liver fibrosis among the NAFLD cases (F2-F4) using ARFI elastography was 26%. BMI, age of patients and female gender were detected as risk factors for NAFLD." @default.
• W4328049352 created "2023-03-22" @default.
• W4328049352 creator A5003446568 @default.
• W4328049352 creator A5005340326 @default.
• W4328049352 creator A5013024051 @default.
• W4328049352 creator A5021193991 @default.
• W4328049352 creator A5035980964 @default.
• W4328049352 creator A5043302929 @default.
• W4328049352 creator A5045594449 @default.
• W4328049352 creator A5074160465 @default.
• W4328049352 creator A5075762100 @default.
• W4328049352 creator A5091331890 @default.
• W4328049352 date "2023-03-21" @default.
• W4328049352 modified "2023-10-08" @default.
• W4328049352 title "Clinical and diagnostic characteristics of non-alcoholic fatty liver disease among Egyptian children and adolescents with type1 diabetes" @default.
• W4328049352 cites W1761288624 @default.
• W4328049352 cites W1966224744 @default.
• W4328049352 cites W1967932879 @default.
• W4328049352 cites W1976137269 @default.
• W4328049352 cites W1976173209 @default.
• W4328049352 cites W2001877414 @default.
• W4328049352 cites W2004023916 @default.
• W4328049352 cites W2015631930 @default.
• W4328049352 cites W2025106732 @default.
• W4328049352 cites W2026706260 @default.
• W4328049352 cites W2040707641 @default.
• W4328049352 cites W2049354336 @default.
• W4328049352 cites W2059613020 @default.
• W4328049352 cites W2063288604 @default.
• W4328049352 cites W2068103659 @default.
• W4328049352 cites W2106061083 @default.
• W4328049352 cites W2114168045 @default.
• W4328049352 cites W2137363797 @default.
• W4328049352 cites W2155104537 @default.
• W4328049352 cites W2269360412 @default.
• W4328049352 cites W2522936083 @default.
• W4328049352 cites W2561776078 @default.
• W4328049352 cites W2589121957 @default.
• W4328049352 cites W2611354168 @default.
• W4328049352 cites W2719803980 @default.
• W4328049352 cites W2734724639 @default.
• W4328049352 cites W2744182009 @default.
• W4328049352 cites W2744982526 @default.
• W4328049352 cites W2884840705 @default.
• W4328049352 cites W2889932786 @default.
• W4328049352 cites W2891777639 @default.
• W4328049352 cites W2895194370 @default.
• W4328049352 cites W2900374812 @default.
• W4328049352 cites W2923636398 @default.
• W4328049352 cites W2954879805 @default.
• W4328049352 cites W3080093778 @default.
• W4328049352 cites W3094553021 @default.
• W4328049352 cites W3101805116 @default.
• W4328049352 cites W3110750499 @default.
• W4328049352 cites W3118583667 @default.
• W4328049352 cites W3120153091 @default.
• W4328049352 cites W3143409077 @default.
• W4328049352 cites W3169135538 @default.
• W4328049352 cites W3204014020 @default.
• W4328049352 cites W3209387560 @default.
• W4328049352 cites W4205381097 @default.
• W4328049352 cites W4246978079 @default.
• W4328049352 doi "https://doi.org/10.1186/s13098-023-01029-6" @default.
• W4328049352 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36941617" @default.
• W4328049352 hasPublicationYear "2023" @default.
• W4328049352 type Work @default.
• W4328049352 citedByCount "0" @default.
• W4328049352 crossrefType "journal-article" @default.
• W4328049352 hasAuthorship W4328049352A5003446568 @default.
• W4328049352 hasAuthorship W4328049352A5005340326 @default.
• W4328049352 hasAuthorship W4328049352A5013024051 @default.
• W4328049352 hasAuthorship W4328049352A5021193991 @default.
• W4328049352 hasAuthorship W4328049352A5035980964 @default.
• W4328049352 hasAuthorship W4328049352A5043302929 @default.
• W4328049352 hasAuthorship W4328049352A5045594449 @default.
• W4328049352 hasAuthorship W4328049352A5074160465 @default.
• W4328049352 hasAuthorship W4328049352A5075762100 @default.
• W4328049352 hasAuthorship W4328049352A5091331890 @default.
• W4328049352 hasBestOaLocation W43280493521 @default.
• W4328049352 hasConcept C126322002 @default.
• W4328049352 hasConcept C134018914 @default.
• W4328049352 hasConcept C2776175330 @default.
• W4328049352 hasConcept C2776193436 @default.
• W4328049352 hasConcept C2777180221 @default.
• W4328049352 hasConcept C2778163477 @default.
• W4328049352 hasConcept C2778270857 @default.
• W4328049352 hasConcept C2778772119 @default.
• W4328049352 hasConcept C2779134260 @default.
• W4328049352 hasConcept C2779478299 @default.
• W4328049352 hasConcept C2780221984 @default.
• W4328049352 hasConcept C555293320 @default.
• W4328049352 hasConcept C71924100 @default.
• W4328049352 hasConcept C90924648 @default.
• W4328049352 hasConceptScore W4328049352C126322002 @default.
• W4328049352 hasConceptScore W4328049352C134018914 @default.
• W4328049352 hasConceptScore W4328049352C2776175330 @default.
• W4328049352 hasConceptScore W4328049352C2776193436 @default.
• W4328049352 hasConceptScore W4328049352C2777180221 @default.
• W4328049352 hasConceptScore W4328049352C2778163477 @default.
• W4328049352 hasConceptScore W4328049352C2778270857 @default.

• next