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- W4328053591 abstract "Hippocampal CA1 neurons respond to sensory stimuli during enforced immobility, movement, and their transitions in a new conveyor belt task. Head-fixed mice were exposed to light flashes or air streams while at rest, spontaneously moving, or running a fixed distance. Two-photon calcium imaging of CA1 neurons revealed that 62% of 3341 imaged cells were active during one or more of 20 sensorimotor events. Of these active cells, 17% were active for any given sensorimotor event, with a higher proportion during locomotion. The study found two types of cells: Conjunctive cells that were active across multiple events, and complementary cells that were active only during individual events, encoding novel sensorimotor events or their delayed repetitions. The configuration of these cells across changing sensorimotor events may signify the role of hippocampus in functional networks integrating sensory information with ongoing movement making it suitable for movement guidance." @default.
- W4328053591 created "2023-03-22" @default.
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- W4328053591 date "2023-04-01" @default.
- W4328053591 modified "2023-10-14" @default.
- W4328053591 title "Hippocampal conjunctive and complementary CA1 populations relate sensory events to movement" @default.
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- W4328053591 doi "https://doi.org/10.1016/j.isci.2023.106481" @default.
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