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- W4328101666 abstract "Literature encloses numerous systematic reviews (SRs) on nonpharmacologic interventions for improving cancer-related fatigue (CRF). The effect of these interventions remains controversial, and the available SRs have not been synthesized yet. We conducted a systematic synthesis of SRs and meta-analysis to determine the effect of nonpharmacologic interventions on CRF in adults.We systematically searched 4 databases. The effect sizes (standard mean difference) were quantitatively pooled using a random-effects model. Chi-squared (Q) and I-square statistics (I²) tested the heterogeneity.We selected 28 SRs, including 35 eligible meta-analyses. The pooled effect size (standard mean difference, 95% CI) was -0.67 (-1.16, -0.18). The subgroup analysis by types of interventions showed a significant effect in all the investigated approaches (complementary integrative medicine, physical exercise, self-management/e-health interventions).There is evidence that nonpharmacologic interventions are associated with CRF reduction. Future research should focus on testing these interventions on specific population clusters and trajectories.CRD42020194258." @default.
- W4328101666 created "2023-03-22" @default.
- W4328101666 creator A5021084962 @default.
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- W4328101666 creator A5051381153 @default.
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- W4328101666 creator A5062475478 @default.
- W4328101666 creator A5063262160 @default.
- W4328101666 creator A5090333092 @default.
- W4328101666 date "2023-02-01" @default.
- W4328101666 modified "2023-09-23" @default.
- W4328101666 title "Non-pharmacologic interventions for improving cancer-related fatigue (CRF): A systematic review of systematic reviews and pooled meta-analysis" @default.
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