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• W4328101917 endingPage "108544" @default.
• W4328101917 startingPage "108544" @default.
• W4328101917 abstract "Empathy is an intricate ability that entails the subjective feeling and understanding of emotions someone else may be experiencing. Acetaminophen, the active ingredient found in Tylenol, is among the most common pain medications consumed. There is new evidence, however, that suggests this common analgesic may also dampen empathic processes. However, no previous study has investigated the effect acetaminophen may have on pain empathy or mu power during a pain empathy task. Therefore, participants were randomly assigned to either an experimental (acetaminophen) or control (sugar) group in a double-blinded experimental research design aimed to measure mu power, using EEG, and behavioral responses to painful and non-painful images. Participants in the experimental group were administered 1000 mg of acetaminophen, and it was verified that participants were unaware of their group assignment. We found that mu suppression was greater in the acetaminophen group, which was strongest at electrode C3. Additionally, mu power differences between painful and non-painful images were related to trait empathy, and mu power during the painful images were positively correlated with empathy scores. Results from this study suggest that in addition to reducing physical pain, acetaminophen may also change the neural response when perceiving others in pain. The implications of these findings could possibly lead to changes in how we prescribe and administer this common drug." @default.
• W4328101917 created "2023-03-22" @default.
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• W4328101917 date "2023-06-01" @default.
• W4328101917 modified "2023-10-01" @default.
• W4328101917 title "Acetaminophen changes Mu rhythm power related to pain empathy" @default.
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• W4328101917 doi "https://doi.org/10.1016/j.neuropsychologia.2023.108544" @default.
• W4328101917 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36948452" @default.
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