Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328102516> ?p ?o ?g. }
- W4328102516 abstract "Abstract Oxytocin is a hormone with functions in: reproduction, maternal bonding, milk ejection, and feeding/social behavior, and is reported to be present in a variety of tissues. Our goal is to characterize oxytocin and leucyl and cystinyl aminopeptidase (LNPEP/oxytocinase), a key regulator of oxytocin in mares. We measured serum and tissue LNPEP by ELISA from ovulation (D0) until D21–22 in non-pregnant (n = 5) and pregnant mares (n = 6); and in periparturient and postpartum mares (n = 18). Placenta (n = 7) and homogenized tissue of diestrus mares (n = 6) were evaluated using protein determinations and LNPEP ELISAs. Identification of LNPEP and OXT protein in tissues was also performed via western blot, immunohistochemistry and liquid chromatography-mass spectrometry (LC-MS/MS). Furthermore, in situ hybridization was performed for LNPEP and OXT on endometrium, myometrium, pituitary and corpus luteum (CL). Serum LNPEP concentration were similar. Placental LNPEP U/mg protein was highest in the body and pregnant horn. The highest to lowest LNPEP U/mg protein by tissue were: myometrium > follicle wall > endometrium > kidney > CL > liver. Oxytocin was identified in the equine pituitary, CL and placenta and is likely to act in autocrine or paracrine manner, while LNPEP may act systemically and locally to regulate the availability of OXT." @default.
- W4328102516 created "2023-03-22" @default.
- W4328102516 creator A5007275052 @default.
- W4328102516 creator A5044015615 @default.
- W4328102516 creator A5045652188 @default.
- W4328102516 creator A5048728975 @default.
- W4328102516 creator A5056118165 @default.
- W4328102516 creator A5061528639 @default.
- W4328102516 creator A5078050404 @default.
- W4328102516 creator A5088532607 @default.
- W4328102516 date "2023-03-21" @default.
- W4328102516 modified "2023-09-24" @default.
- W4328102516 title "Characterization of serum and tissue oxytocinase and tissue oxytocin in the pregnant and non-pregnant mare" @default.
- W4328102516 cites W1507117580 @default.
- W4328102516 cites W1602804419 @default.
- W4328102516 cites W182464801 @default.
- W4328102516 cites W1968707595 @default.
- W4328102516 cites W1972756133 @default.
- W4328102516 cites W1979985076 @default.
- W4328102516 cites W1981917442 @default.
- W4328102516 cites W1982713057 @default.
- W4328102516 cites W1997400032 @default.
- W4328102516 cites W2000815805 @default.
- W4328102516 cites W2001258970 @default.
- W4328102516 cites W2007310652 @default.
- W4328102516 cites W2011549099 @default.
- W4328102516 cites W2023892321 @default.
- W4328102516 cites W2027610211 @default.
- W4328102516 cites W2033841747 @default.
- W4328102516 cites W2042700221 @default.
- W4328102516 cites W2049609626 @default.
- W4328102516 cites W2052882183 @default.
- W4328102516 cites W2053488589 @default.
- W4328102516 cites W2053877590 @default.
- W4328102516 cites W2063897756 @default.
- W4328102516 cites W2073531113 @default.
- W4328102516 cites W2075387690 @default.
- W4328102516 cites W2078496789 @default.
- W4328102516 cites W2080113379 @default.
- W4328102516 cites W2093590606 @default.
- W4328102516 cites W2093808777 @default.
- W4328102516 cites W2094290147 @default.
- W4328102516 cites W2097063131 @default.
- W4328102516 cites W2098488805 @default.
- W4328102516 cites W2118295366 @default.
- W4328102516 cites W2121188624 @default.
- W4328102516 cites W2137128752 @default.
- W4328102516 cites W2155675564 @default.
- W4328102516 cites W2168161193 @default.
- W4328102516 cites W2181983966 @default.
- W4328102516 cites W2316741456 @default.
- W4328102516 cites W2327545152 @default.
- W4328102516 cites W2335685900 @default.
- W4328102516 cites W2519924201 @default.
- W4328102516 cites W2590694123 @default.
- W4328102516 cites W2800587022 @default.
- W4328102516 cites W2905550988 @default.
- W4328102516 cites W2917288137 @default.
- W4328102516 cites W2945572346 @default.
- W4328102516 cites W2950919157 @default.
- W4328102516 cites W2986135686 @default.
- W4328102516 cites W3208691473 @default.
- W4328102516 cites W4212905190 @default.
- W4328102516 cites W4220833388 @default.
- W4328102516 cites W4294326300 @default.
- W4328102516 cites W4306687521 @default.
- W4328102516 doi "https://doi.org/10.1038/s41598-023-31540-9" @default.
- W4328102516 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36944665" @default.
- W4328102516 hasPublicationYear "2023" @default.
- W4328102516 type Work @default.
- W4328102516 citedByCount "1" @default.
- W4328102516 countsByYear W43281025162023 @default.
- W4328102516 crossrefType "journal-article" @default.
- W4328102516 hasAuthorship W4328102516A5007275052 @default.
- W4328102516 hasAuthorship W4328102516A5044015615 @default.
- W4328102516 hasAuthorship W4328102516A5045652188 @default.
- W4328102516 hasAuthorship W4328102516A5048728975 @default.
- W4328102516 hasAuthorship W4328102516A5056118165 @default.
- W4328102516 hasAuthorship W4328102516A5061528639 @default.
- W4328102516 hasAuthorship W4328102516A5078050404 @default.
- W4328102516 hasAuthorship W4328102516A5088532607 @default.
- W4328102516 hasBestOaLocation W43281025161 @default.
- W4328102516 hasConcept C104317684 @default.
- W4328102516 hasConcept C126322002 @default.
- W4328102516 hasConcept C134018914 @default.
- W4328102516 hasConcept C16685009 @default.
- W4328102516 hasConcept C172680121 @default.
- W4328102516 hasConcept C185592680 @default.
- W4328102516 hasConcept C2776176026 @default.
- W4328102516 hasConcept C2776415932 @default.
- W4328102516 hasConcept C2776608385 @default.
- W4328102516 hasConcept C2776953305 @default.
- W4328102516 hasConcept C2777658017 @default.
- W4328102516 hasConcept C2777702977 @default.
- W4328102516 hasConcept C2778164554 @default.
- W4328102516 hasConcept C2779066055 @default.
- W4328102516 hasConcept C2779234561 @default.
- W4328102516 hasConcept C2779742232 @default.
- W4328102516 hasConcept C2780197806 @default.
- W4328102516 hasConcept C2780297037 @default.