Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328103255> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W4328103255 endingPage "115244" @default.
- W4328103255 startingPage "115244" @default.
- W4328103255 abstract "Antimonite (SbIII) is a naturally occurring contaminant demanding on-site ultrasensitive detection. The enzyme-based electrochemical (EC) biosensors are promising, but the lack of specific SbIII oxidizing enzymes hindered the past efforts. Herein, we modulated the specificity of arsenite oxidase AioAB toward SbIII by regulating its spatial conformation from tight to loose using the metal-organic framework ZIF-8. The constructed EC biosensor, AioAB@ZIF-8, exhibited the substrate specificity toward SbIII at 12.8 s-1 μM-1, an order of magnitude higher than that of AsIII (1.1 s-1 μM-1). Relaxing AioAB structure in ZIF-8 was evidenced by the break of the S-S bond and the conversion of α helix to the random coil as suggested by Raman spectroscopy. Our AioAB@ZIF-8 EC sensor exhibited a dynamic linear range in 0.041-4.1 μM at a response time of 5 s, and the detection limit at 0.041 μM at a high sensitivity of 1894 nA μM-1. The insights into tuning the specificity of an enzyme shed new light on biosensing metal(loid)s without specific proteins." @default.
- W4328103255 created "2023-03-22" @default.
- W4328103255 creator A5013973657 @default.
- W4328103255 creator A5021379425 @default.
- W4328103255 creator A5058418215 @default.
- W4328103255 date "2023-06-01" @default.
- W4328103255 modified "2023-10-04" @default.
- W4328103255 title "Enzyme-based electrochemical biosensor for antimonite detection in water" @default.
- W4328103255 cites W1973658255 @default.
- W4328103255 cites W2010069413 @default.
- W4328103255 cites W2035648603 @default.
- W4328103255 cites W2047503883 @default.
- W4328103255 cites W2130384960 @default.
- W4328103255 cites W2137336212 @default.
- W4328103255 cites W2138230100 @default.
- W4328103255 cites W2324545272 @default.
- W4328103255 cites W2522928546 @default.
- W4328103255 cites W2614884348 @default.
- W4328103255 cites W2620154704 @default.
- W4328103255 cites W2751217839 @default.
- W4328103255 cites W2805528242 @default.
- W4328103255 cites W2886246069 @default.
- W4328103255 cites W2886922898 @default.
- W4328103255 cites W3000509091 @default.
- W4328103255 cites W3011592873 @default.
- W4328103255 cites W3016174941 @default.
- W4328103255 cites W3026042919 @default.
- W4328103255 cites W3093424131 @default.
- W4328103255 cites W3099538464 @default.
- W4328103255 cites W3118806859 @default.
- W4328103255 cites W3151895458 @default.
- W4328103255 cites W3198427966 @default.
- W4328103255 cites W3203361017 @default.
- W4328103255 cites W3208040520 @default.
- W4328103255 cites W4285821049 @default.
- W4328103255 cites W4309326934 @default.
- W4328103255 doi "https://doi.org/10.1016/j.bios.2023.115244" @default.
- W4328103255 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36966618" @default.
- W4328103255 hasPublicationYear "2023" @default.
- W4328103255 type Work @default.
- W4328103255 citedByCount "1" @default.
- W4328103255 crossrefType "journal-article" @default.
- W4328103255 hasAuthorship W4328103255A5013973657 @default.
- W4328103255 hasAuthorship W4328103255A5021379425 @default.
- W4328103255 hasAuthorship W4328103255A5058418215 @default.
- W4328103255 hasConcept C119128265 @default.
- W4328103255 hasConcept C120665830 @default.
- W4328103255 hasConcept C121332964 @default.
- W4328103255 hasConcept C160756335 @default.
- W4328103255 hasConcept C178790620 @default.
- W4328103255 hasConcept C185592680 @default.
- W4328103255 hasConcept C2776305511 @default.
- W4328103255 hasConcept C40003534 @default.
- W4328103255 hasConcept C43617362 @default.
- W4328103255 hasConcept C502230775 @default.
- W4328103255 hasConcept C55493867 @default.
- W4328103255 hasConcept C77176794 @default.
- W4328103255 hasConceptScore W4328103255C119128265 @default.
- W4328103255 hasConceptScore W4328103255C120665830 @default.
- W4328103255 hasConceptScore W4328103255C121332964 @default.
- W4328103255 hasConceptScore W4328103255C160756335 @default.
- W4328103255 hasConceptScore W4328103255C178790620 @default.
- W4328103255 hasConceptScore W4328103255C185592680 @default.
- W4328103255 hasConceptScore W4328103255C2776305511 @default.
- W4328103255 hasConceptScore W4328103255C40003534 @default.
- W4328103255 hasConceptScore W4328103255C43617362 @default.
- W4328103255 hasConceptScore W4328103255C502230775 @default.
- W4328103255 hasConceptScore W4328103255C55493867 @default.
- W4328103255 hasConceptScore W4328103255C77176794 @default.
- W4328103255 hasFunder F4320321001 @default.
- W4328103255 hasLocation W43281032551 @default.
- W4328103255 hasLocation W43281032552 @default.
- W4328103255 hasOpenAccess W4328103255 @default.
- W4328103255 hasPrimaryLocation W43281032551 @default.
- W4328103255 hasRelatedWork W2067083244 @default.
- W4328103255 hasRelatedWork W2113221713 @default.
- W4328103255 hasRelatedWork W2145078881 @default.
- W4328103255 hasRelatedWork W2182018558 @default.
- W4328103255 hasRelatedWork W2357266277 @default.
- W4328103255 hasRelatedWork W2970824804 @default.
- W4328103255 hasRelatedWork W3005489415 @default.
- W4328103255 hasRelatedWork W3203235745 @default.
- W4328103255 hasRelatedWork W3204365266 @default.
- W4328103255 hasRelatedWork W4234954000 @default.
- W4328103255 hasVolume "229" @default.
- W4328103255 isParatext "false" @default.
- W4328103255 isRetracted "false" @default.
- W4328103255 workType "article" @default.