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- W4328103737 abstract "Lentivirus is an efficient gene transfer system that is widely used in basic science. We aimed to improve viral titer by applying an ultra-expression vectors to lentiviral packaging. Application of the ultra-expression vectors increased biological titer 4 times for standard preparation. We also evaluated the efficacy of the ultra-expression vectors to relatively longer insert fragments, such as CSII-CMV-CNROE containing 5 genes in multiple cloning sites. Packaging of the ultra-expression vectors showed 3.5 times higher biological titer compared with the original method. Our improved packaging system could be applied to lentivirus to produce higher titers." @default.
- W4328103737 created "2023-03-22" @default.
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- W4328103737 date "2023-05-01" @default.
- W4328103737 modified "2023-09-27" @default.
- W4328103737 title "Increased lentivirus titer using ultra expression vectors" @default.
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- W4328103737 doi "https://doi.org/10.1016/j.ab.2023.115119" @default.
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