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- W4328103780 abstract "Screening for α-glucosidase inhibitors and antioxidants from natural sources that could reduce postprandial glucose in diabetic patients and reduce oxidative stress had attracted considerable interest. In this study, a neutral polysaccharide (AP-1) with a triple helix structure was isolated and purified from the residue of apricot (Armeniaca sibirica L. Lam.) kernels by using DEAE-52 and Sephadex G-100 columns. The molecular weight of AP-1 was 23.408 kDa and consisted mainly of glucose with trace amounts of arabinose, galactose, and mannose, which had molar percentages of 98.48, 0.63, 0.62 and 0.27 %, respectively. The main chain of AP-1 was composed of →4)-α-D-Glcp-(1 → interlinked, and α-D-Glcp-(1 → was attached as a branched chain at the O-6 position of →4,6)-α-D-Glcp-(1→. In addition, AP-1 exhibited stronger α-glucosidase inhibition and free radical scavenging ability compared to crude polysaccharides. Therefore, AP-1 could be used as a potential natural hypoglycemic agent and antioxidant in the treatment of diabetes mellitus." @default.
- W4328103780 created "2023-03-22" @default.
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- W4328103780 date "2023-05-01" @default.
- W4328103780 modified "2023-09-28" @default.
- W4328103780 title "Structural characterization, α-glucosidase inhibitory activity and antioxidant activity of neutral polysaccharide from apricot (Armeniaca Sibirica L. Lam) kernels" @default.
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- W4328103780 doi "https://doi.org/10.1016/j.ijbiomac.2023.124109" @default.
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