FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328104912> ?p ?o ?g. }

• W4328104912 endingPage "235" @default.
• W4328104912 startingPage "235" @default.
• W4328104912 abstract "The macrophage CD163 surface glycoprotein is a member of the SRCR family class B, which has been identified as the key trigger in host–pathogen interactions, but its specific roles in sensing Glaesserella parasuis (G. parasuis) infection are largely unknown. Here, we investigated porcine CD163 in mediating the adhesion and immune response of G. parasuis using in vitro host–bacteria interaction models. CD163-overexpressing Chinese hamster ovary K1 cells (CHO-K1) showed obvious subcellular localization in the cytoplasm, especially in the cytomembrane. Although detection using scanning electron microscopy (SEM) confirmed the bacterial adhesion, there was no significant difference in the adhesion of G. parasuis to CHO-K1 cells between the presence and absence of CD163. In addition, similar results were observed in 3D4/21 cells. Meanwhile, bindings of G. parasuis to nine synthetic peptides, the bacterial binding motifs within SRCR domains of CD163, were weak based on a solid-phase adhesion assay and agglutination assay. Moreover, CD163 had no effect on the expression of G. parasuis-induced inflammatory cytokines (IL-6, INF-γ, IL-10, IL-4 and TGF-β) in CHO-K1 cells. In conclusion, these findings indicate that porcine CD163 plays a minor role in sensing G. parasuis infection." @default.
• W4328104912 created "2023-03-22" @default.
• W4328104912 creator A5011940376 @default.
• W4328104912 creator A5017947172 @default.
• W4328104912 creator A5026793278 @default.
• W4328104912 creator A5038984455 @default.
• W4328104912 creator A5048366872 @default.
• W4328104912 creator A5072346835 @default.
• W4328104912 creator A5080276547 @default.
• W4328104912 creator A5086405196 @default.
• W4328104912 creator A5090819748 @default.
• W4328104912 date "2023-03-21" @default.
• W4328104912 modified "2023-10-18" @default.
• W4328104912 title "Assessment of the Macrophage Scavenger Receptor CD163 in Mediating Glaesserella parasuis Infection of Host Cells" @default.
• W4328104912 cites W1510971871 @default.
• W4328104912 cites W1965206243 @default.
• W4328104912 cites W1971587134 @default.
• W4328104912 cites W1987112471 @default.
• W4328104912 cites W2014471477 @default.
• W4328104912 cites W2027812455 @default.
• W4328104912 cites W2105977856 @default.
• W4328104912 cites W2108244474 @default.
• W4328104912 cites W2109313325 @default.
• W4328104912 cites W2121057200 @default.
• W4328104912 cites W2128498632 @default.
• W4328104912 cites W2133640250 @default.
• W4328104912 cites W2146524990 @default.
• W4328104912 cites W2512595727 @default.
• W4328104912 cites W2519383378 @default.
• W4328104912 cites W2539400224 @default.
• W4328104912 cites W2589917284 @default.
• W4328104912 cites W2765439690 @default.
• W4328104912 cites W2782845207 @default.
• W4328104912 cites W2805302320 @default.
• W4328104912 cites W2807795334 @default.
• W4328104912 cites W2883604145 @default.
• W4328104912 cites W2892106792 @default.
• W4328104912 cites W2938053196 @default.
• W4328104912 cites W2979813383 @default.
• W4328104912 cites W3028862709 @default.
• W4328104912 cites W3102009779 @default.
• W4328104912 cites W3151893855 @default.
• W4328104912 cites W4210975044 @default.
• W4328104912 cites W4286264989 @default.
• W4328104912 cites W4296168404 @default.
• W4328104912 cites W4307633592 @default.
• W4328104912 doi "https://doi.org/10.3390/vetsci10030235" @default.
• W4328104912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36977274" @default.
• W4328104912 hasPublicationYear "2023" @default.
• W4328104912 type Work @default.
• W4328104912 citedByCount "1" @default.
• W4328104912 countsByYear W43281049122023 @default.
• W4328104912 crossrefType "journal-article" @default.
• W4328104912 hasAuthorship W4328104912A5011940376 @default.
• W4328104912 hasAuthorship W4328104912A5017947172 @default.
• W4328104912 hasAuthorship W4328104912A5026793278 @default.
• W4328104912 hasAuthorship W4328104912A5038984455 @default.
• W4328104912 hasAuthorship W4328104912A5048366872 @default.
• W4328104912 hasAuthorship W4328104912A5072346835 @default.
• W4328104912 hasAuthorship W4328104912A5080276547 @default.
• W4328104912 hasAuthorship W4328104912A5086405196 @default.
• W4328104912 hasAuthorship W4328104912A5090819748 @default.
• W4328104912 hasBestOaLocation W43281049121 @default.
• W4328104912 hasConcept C104317684 @default.
• W4328104912 hasConcept C108625454 @default.
• W4328104912 hasConcept C153911025 @default.
• W4328104912 hasConcept C170493617 @default.
• W4328104912 hasConcept C175656101 @default.
• W4328104912 hasConcept C178790620 @default.
• W4328104912 hasConcept C185592680 @default.
• W4328104912 hasConcept C190062978 @default.
• W4328104912 hasConcept C202751555 @default.
• W4328104912 hasConcept C203014093 @default.
• W4328104912 hasConcept C2775858924 @default.
• W4328104912 hasConcept C2776460866 @default.
• W4328104912 hasConcept C2778163477 @default.
• W4328104912 hasConcept C2779244956 @default.
• W4328104912 hasConcept C2780072125 @default.
• W4328104912 hasConcept C41443022 @default.
• W4328104912 hasConcept C55493867 @default.
• W4328104912 hasConcept C60987743 @default.
• W4328104912 hasConcept C84416704 @default.
• W4328104912 hasConcept C86803240 @default.
• W4328104912 hasConcept C8891405 @default.
• W4328104912 hasConcept C89423630 @default.
• W4328104912 hasConcept C95444343 @default.
• W4328104912 hasConceptScore W4328104912C104317684 @default.
• W4328104912 hasConceptScore W4328104912C108625454 @default.
• W4328104912 hasConceptScore W4328104912C153911025 @default.
• W4328104912 hasConceptScore W4328104912C170493617 @default.
• W4328104912 hasConceptScore W4328104912C175656101 @default.
• W4328104912 hasConceptScore W4328104912C178790620 @default.
• W4328104912 hasConceptScore W4328104912C185592680 @default.
• W4328104912 hasConceptScore W4328104912C190062978 @default.
• W4328104912 hasConceptScore W4328104912C202751555 @default.
• W4328104912 hasConceptScore W4328104912C203014093 @default.
• W4328104912 hasConceptScore W4328104912C2775858924 @default.
• W4328104912 hasConceptScore W4328104912C2776460866 @default.

• next