FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328104972> ?p ?o ?g. }

• W4328104972 abstract "Yellowtail kingfish has emerged as one of the most promising marine fishes for aquaculture in China because it is tasty, fast growing, and has high economic value. To investigate the tolerance and adaptability to hypoxia of farmed yellowtail kingfish, juveniles were exposed to hypoxia (3.0 ± 0.5 mg/L) for 5 days and then returned to normoxia (7.5 ± 0.5 mg/L) for another 5 days. Using tissue sections and high-throughput sequencing technology, we investigated the histological, microecological, transcriptomic, and physiological adaptation mechanisms of yellowtail kingfish. The results showed that hypoxia increased the gill lamellae length and spacing, which were reversible post-reoxygenation. At the genus level, the relative abundances of Prevotella , Bacteroides , Roseburia , and Blautia in the gastrointestinal tract increased under hypoxia and were maintained post-reoxygenation. The liver transcriptome revealed that, compared with normoxia group, the different expression genes (DEGs) were mainly enriched in Steroid biosynthesis and PPAR signaling pathways in hypoxia group. Compared with normoxia group, the DEGs were mainly enriched in Ribosome biogenesis in eukaryotes, Steroid biosynthesis, Fatty acid biosynthesis, and PPAR signaling pathways in reoxygenation group. Furthermore, compared with hypoxia group, the DEGs were mainly enriched in Ribosome biogenesis in eukaryotes and Ribosome pathways in reoxygenation group. In contrast to normoxia, of the key genes of the PPAR signaling pathway, FABP4 was significantly downregulated, and SCD-1 and FATP were significantly upregulated. These findings indicated reduced lipid deposition and increased lipid decomposition in liver under hypoxia. The genes including PPARα , SCD-1 , ANGPTL4 , and FASN were significantly upregulated in lipid metabolism-related pathways, which indicated that lipid metabolism activity was more vigorous during reoxygenation. In contrast to the hypoxia group, almost all of the genes involved in Ribosome biogenesis in eukaryotes and Ribosome pathways for protein processing were significantly upregulated during reoxygenation; this is probably related to the clearance of misfolded proteins and the folding of the new proteins repairing there is damage to the body. The present results shed light on the possible synergetic function of lipid metabolism, protein repairment and synthesis, and gastrointestinal microbiota in resistance and homeostasis maintenance of yellowtail kingfish coping with hypoxic stress in aquaculture." @default.
• W4328104972 created "2023-03-22" @default.
• W4328104972 creator A5005181023 @default.
• W4328104972 creator A5027218700 @default.
• W4328104972 creator A5035443305 @default.
• W4328104972 creator A5039881925 @default.
• W4328104972 creator A5053911691 @default.
• W4328104972 creator A5061812566 @default.
• W4328104972 creator A5083665752 @default.
• W4328104972 date "2023-03-21" @default.
• W4328104972 modified "2023-10-18" @default.
• W4328104972 title "Histological, microecological and transcriptomic physiological responses underlying hypoxia and reoxygenation adaptation in yellowtail kingfish (Seriola lalandi)" @default.
• W4328104972 cites W1966105954 @default.
• W4328104972 cites W1975541489 @default.
• W4328104972 cites W1988656570 @default.
• W4328104972 cites W1999574084 @default.
• W4328104972 cites W2006862211 @default.
• W4328104972 cites W2010654843 @default.
• W4328104972 cites W2027847170 @default.
• W4328104972 cites W2033751418 @default.
• W4328104972 cites W2039031569 @default.
• W4328104972 cites W2050291872 @default.
• W4328104972 cites W2051854060 @default.
• W4328104972 cites W2054497994 @default.
• W4328104972 cites W2064178384 @default.
• W4328104972 cites W2069699035 @default.
• W4328104972 cites W2072920872 @default.
• W4328104972 cites W2072970694 @default.
• W4328104972 cites W2078434599 @default.
• W4328104972 cites W2082636978 @default.
• W4328104972 cites W2098534246 @default.
• W4328104972 cites W2101606890 @default.
• W4328104972 cites W2112961075 @default.
• W4328104972 cites W2135878067 @default.
• W4328104972 cites W2136778785 @default.
• W4328104972 cites W2148173519 @default.
• W4328104972 cites W2157107905 @default.
• W4328104972 cites W2169195347 @default.
• W4328104972 cites W2170291426 @default.
• W4328104972 cites W2171016495 @default.
• W4328104972 cites W2179438025 @default.
• W4328104972 cites W2260859913 @default.
• W4328104972 cites W2277636960 @default.
• W4328104972 cites W2312709202 @default.
• W4328104972 cites W2345460740 @default.
• W4328104972 cites W2347000244 @default.
• W4328104972 cites W2609314180 @default.
• W4328104972 cites W2624814527 @default.
• W4328104972 cites W2740186645 @default.
• W4328104972 cites W2805323353 @default.
• W4328104972 cites W2911747707 @default.
• W4328104972 cites W2941367344 @default.
• W4328104972 cites W2944650448 @default.
• W4328104972 cites W2951912016 @default.
• W4328104972 cites W2989776928 @default.
• W4328104972 cites W2990126512 @default.
• W4328104972 cites W3120247780 @default.
• W4328104972 cites W3123875715 @default.
• W4328104972 cites W3123936538 @default.
• W4328104972 cites W3126519734 @default.
• W4328104972 cites W3127288224 @default.
• W4328104972 cites W3141609492 @default.
• W4328104972 cites W3158406147 @default.
• W4328104972 cites W4210377299 @default.
• W4328104972 cites W4224246635 @default.
• W4328104972 cites W4281261248 @default.
• W4328104972 cites W4283693126 @default.
• W4328104972 cites W4296794610 @default.
• W4328104972 doi "https://doi.org/10.3389/fmars.2023.1121866" @default.
• W4328104972 hasPublicationYear "2023" @default.
• W4328104972 type Work @default.
• W4328104972 citedByCount "0" @default.
• W4328104972 crossrefType "journal-article" @default.
• W4328104972 hasAuthorship W4328104972A5005181023 @default.
• W4328104972 hasAuthorship W4328104972A5027218700 @default.
• W4328104972 hasAuthorship W4328104972A5035443305 @default.
• W4328104972 hasAuthorship W4328104972A5039881925 @default.
• W4328104972 hasAuthorship W4328104972A5053911691 @default.
• W4328104972 hasAuthorship W4328104972A5061812566 @default.
• W4328104972 hasAuthorship W4328104972A5083665752 @default.
• W4328104972 hasBestOaLocation W43281049721 @default.
• W4328104972 hasConcept C104317684 @default.
• W4328104972 hasConcept C150194340 @default.
• W4328104972 hasConcept C162317418 @default.
• W4328104972 hasConcept C178790620 @default.
• W4328104972 hasConcept C185592680 @default.
• W4328104972 hasConcept C540031477 @default.
• W4328104972 hasConcept C55493867 @default.
• W4328104972 hasConcept C7836513 @default.
• W4328104972 hasConcept C86803240 @default.
• W4328104972 hasConceptScore W4328104972C104317684 @default.
• W4328104972 hasConceptScore W4328104972C150194340 @default.
• W4328104972 hasConceptScore W4328104972C162317418 @default.
• W4328104972 hasConceptScore W4328104972C178790620 @default.
• W4328104972 hasConceptScore W4328104972C185592680 @default.
• W4328104972 hasConceptScore W4328104972C540031477 @default.
• W4328104972 hasConceptScore W4328104972C55493867 @default.
• W4328104972 hasConceptScore W4328104972C7836513 @default.
• W4328104972 hasConceptScore W4328104972C86803240 @default.
• W4328104972 hasLocation W43281049721 @default.

• next