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- W4328105384 abstract "The establishment of consistent genetically modified mouse melanoma models and cell lines is of paramount importance for prevention and treatment. In this study, we review the different mouse melanoma cell lines that have been established. After careful molecular characterization of the established mouse melanoma cell lines, modification of the genome, microenvironment, or even the environment using appropriate in cellulo and in vivo assays may reveal novel genetic and nongenetic changes. These murine melanoma cell lines with defined genetic mutations allow the testing of innovative therapies based on chemistry, physics, and biology using alternative methods. In addition to the fundamental aspects, these results are important for humans because of the relevance of these murine melanoma cell lines to human disease." @default.
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- W4328105384 date "2023-04-01" @default.
- W4328105384 modified "2023-10-02" @default.
- W4328105384 title "Derivation and Use of Cell Lines from Mouse Models of Melanoma" @default.
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- W4328105384 doi "https://doi.org/10.1016/j.jid.2023.01.005" @default.
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