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- W4328108197 abstract "The Protein phosphatase 1 catalytic subunit alpha (PPP1CA) is a alpha subunit of the PP1 complex, which known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Here, a PPP1CA knockout human embryonic stem cell line, WAe009-A-B, was generated using the CRISPR/Cas9 system to further study the function of PPP1CA. The cell line confirmed with pluripotency, normal karyotype and differentiation potential." @default.
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- W4328108197 date "2023-06-01" @default.
- W4328108197 modified "2023-10-16" @default.
- W4328108197 title "Generation of a PPP1CA knockout human pluripotent stem cell line via CRISPR/Cas9" @default.
- W4328108197 cites W2066390373 @default.
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- W4328108197 doi "https://doi.org/10.1016/j.scr.2023.103077" @default.
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