Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328110735> ?p ?o ?g. }
- W4328110735 endingPage "5893" @default.
- W4328110735 startingPage "5893" @default.
- W4328110735 abstract "Gomesin is a cationic antimicrobial peptide which is isolated from the haemocytes of the Brazilian tarantula Acanthoscurria gomesiana and can be produced chemically by Fmoc solid-phase peptide synthesis. Gomesin exhibits a range of biological activities, as demonstrated by its toxicity against therapeutically relevant pathogens such as Gram-positive or Gram-negative bacteria, fungi, cancer cells, and parasites. In recent years, a cyclic version of gomesin has been used for drug design and development as it is more stable than native gomesin in human serum and can penetrate and enter cancer cells. It can therefore interact with intracellular targets and has the potential to be developed as a drug lead for to treat cancer, infectious diseases, and other human diseases. This review provides a perspective on the discovery, structure-activity relationships, mechanism of action, biological activity, and potential clinical applications of gomesin." @default.
- W4328110735 created "2023-03-22" @default.
- W4328110735 creator A5008575244 @default.
- W4328110735 creator A5042763637 @default.
- W4328110735 creator A5051238211 @default.
- W4328110735 creator A5079308758 @default.
- W4328110735 date "2023-03-20" @default.
- W4328110735 modified "2023-10-01" @default.
- W4328110735 title "Unlocking the Potential of the Antimicrobial Peptide Gomesin: From Discovery and Structure–Activity Relationships to Therapeutic Applications" @default.
- W4328110735 cites W1019954307 @default.
- W4328110735 cites W1483201238 @default.
- W4328110735 cites W1508119641 @default.
- W4328110735 cites W1535584167 @default.
- W4328110735 cites W1541773479 @default.
- W4328110735 cites W1793299776 @default.
- W4328110735 cites W1929291897 @default.
- W4328110735 cites W1953843785 @default.
- W4328110735 cites W1963683058 @default.
- W4328110735 cites W1964937304 @default.
- W4328110735 cites W1997299931 @default.
- W4328110735 cites W1998692096 @default.
- W4328110735 cites W2007524080 @default.
- W4328110735 cites W2015172163 @default.
- W4328110735 cites W2017136256 @default.
- W4328110735 cites W2037823928 @default.
- W4328110735 cites W2042078619 @default.
- W4328110735 cites W2042350961 @default.
- W4328110735 cites W2054607729 @default.
- W4328110735 cites W2058429414 @default.
- W4328110735 cites W2064283997 @default.
- W4328110735 cites W2067337286 @default.
- W4328110735 cites W2070162626 @default.
- W4328110735 cites W2081513147 @default.
- W4328110735 cites W2118223229 @default.
- W4328110735 cites W2120061656 @default.
- W4328110735 cites W2122627316 @default.
- W4328110735 cites W2125177868 @default.
- W4328110735 cites W2130573571 @default.
- W4328110735 cites W2134329023 @default.
- W4328110735 cites W2138699598 @default.
- W4328110735 cites W2155755979 @default.
- W4328110735 cites W2168356542 @default.
- W4328110735 cites W2301660337 @default.
- W4328110735 cites W2400575045 @default.
- W4328110735 cites W2401557587 @default.
- W4328110735 cites W2586156886 @default.
- W4328110735 cites W2737993499 @default.
- W4328110735 cites W2752513086 @default.
- W4328110735 cites W2763145619 @default.
- W4328110735 cites W2790032805 @default.
- W4328110735 cites W2790583506 @default.
- W4328110735 cites W2796585980 @default.
- W4328110735 cites W2802045337 @default.
- W4328110735 cites W2808652114 @default.
- W4328110735 cites W2884753824 @default.
- W4328110735 cites W2899890541 @default.
- W4328110735 cites W2979238556 @default.
- W4328110735 cites W2979636359 @default.
- W4328110735 cites W3005450802 @default.
- W4328110735 cites W3025642283 @default.
- W4328110735 cites W3048752454 @default.
- W4328110735 cites W3088119082 @default.
- W4328110735 cites W3092909579 @default.
- W4328110735 cites W3137430938 @default.
- W4328110735 cites W3194188670 @default.
- W4328110735 cites W4206677002 @default.
- W4328110735 cites W4212959738 @default.
- W4328110735 cites W4297504185 @default.
- W4328110735 cites W4303699614 @default.
- W4328110735 doi "https://doi.org/10.3390/ijms24065893" @default.
- W4328110735 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36982972" @default.
- W4328110735 hasPublicationYear "2023" @default.
- W4328110735 type Work @default.
- W4328110735 citedByCount "0" @default.
- W4328110735 crossrefType "journal-article" @default.
- W4328110735 hasAuthorship W4328110735A5008575244 @default.
- W4328110735 hasAuthorship W4328110735A5042763637 @default.
- W4328110735 hasAuthorship W4328110735A5051238211 @default.
- W4328110735 hasAuthorship W4328110735A5079308758 @default.
- W4328110735 hasBestOaLocation W43281107351 @default.
- W4328110735 hasConcept C116073593 @default.
- W4328110735 hasConcept C121608353 @default.
- W4328110735 hasConcept C185592680 @default.
- W4328110735 hasConcept C202751555 @default.
- W4328110735 hasConcept C2776120743 @default.
- W4328110735 hasConcept C2779281246 @default.
- W4328110735 hasConcept C2780035454 @default.
- W4328110735 hasConcept C4937899 @default.
- W4328110735 hasConcept C540938839 @default.
- W4328110735 hasConcept C54355233 @default.
- W4328110735 hasConcept C55493867 @default.
- W4328110735 hasConcept C70721500 @default.
- W4328110735 hasConcept C74187038 @default.
- W4328110735 hasConcept C86803240 @default.
- W4328110735 hasConcept C89423630 @default.
- W4328110735 hasConcept C98274493 @default.
- W4328110735 hasConceptScore W4328110735C116073593 @default.
- W4328110735 hasConceptScore W4328110735C121608353 @default.