FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328111523> ?p ?o ?g. }

• W4328111523 endingPage "384" @default.
• W4328111523 startingPage "373" @default.
• W4328111523 abstract "Inhaled corticosteroids (ICS) are associated with an increased risk of clinical pneumonia among patients with chronic obstructive pulmonary disease (COPD). It is unknown whether the risk of microbiologically verified pneumonia such as pneumococcal pneumonia is increased in ICS users.The study population consists of all COPD patients followed in outpatient clinics in eastern Denmark during 2010-2017. ICS use was categorized into four categories based on accumulated use. A Cox proportional hazard regression model was used adjusting for age, body mass index, sex, airflow limitation, use of oral corticosteroids, smoking, and year of cohort entry. A propensity score matched analysis was performed for sensitivity analyses.A total of 21,438 patients were included. Five hundred and eighty-two (2.6%) patients acquired a positive lower airway tract sample with S. pneumoniae during follow-up. In the multivariable analysis ICS-use was associated with a dose-dependent risk of S. pneumoniae as follows: low ICS dose: HR 1.11, 95% CI 0.84 to 1.45, p = 0.5; moderate ICS dose: HR 1.47, 95% CI 1.13 to 1.90, p = 0.004; high ICS dose: HR 1.77, 95% CI 1.38 to 2.29, p < 0.0001, compared to no ICS use. Sensitivity analyses confirmed these results.Use of ICS in patients with severe COPD was associated with an increased and dose-dependent risk of acquiring S. pneumoniae, but only for moderate and high dose. Caution should be taken when administering high dose of ICS to patients with COPD. Low dose of ICS seemed not to carry this risk." @default.
• W4328111523 created "2023-03-22" @default.
• W4328111523 creator A5002472471 @default.
• W4328111523 creator A5005472788 @default.
• W4328111523 creator A5007573133 @default.
• W4328111523 creator A5022531645 @default.
• W4328111523 creator A5024242782 @default.
• W4328111523 creator A5030592903 @default.
• W4328111523 creator A5032444299 @default.
• W4328111523 creator A5035965494 @default.
• W4328111523 creator A5040875204 @default.
• W4328111523 creator A5042252779 @default.
• W4328111523 creator A5044771174 @default.
• W4328111523 creator A5050473424 @default.
• W4328111523 creator A5054989002 @default.
• W4328111523 creator A5057223769 @default.
• W4328111523 creator A5066021887 @default.
• W4328111523 creator A5066100458 @default.
• W4328111523 creator A5074608165 @default.
• W4328111523 creator A5077156587 @default.
• W4328111523 creator A5082017828 @default.
• W4328111523 creator A5087894282 @default.
• W4328111523 date "2023-03-01" @default.
• W4328111523 modified "2023-10-11" @default.
• W4328111523 title "Inhaled Corticosteroids in Patients with Chronic Obstructive Pulmonary Disease and Risk of Acquiring Streptococcus pneumoniae Infection. A Multiregional Epidemiological Study" @default.
• W4328111523 cites W2080276371 @default.
• W4328111523 cites W2102924526 @default.
• W4328111523 cites W2114698211 @default.
• W4328111523 cites W2135688996 @default.
• W4328111523 cites W2139192099 @default.
• W4328111523 cites W2142724633 @default.
• W4328111523 cites W2152520891 @default.
• W4328111523 cites W2165033359 @default.
• W4328111523 cites W2324038222 @default.
• W4328111523 cites W2344148139 @default.
• W4328111523 cites W2544185954 @default.
• W4328111523 cites W2785999277 @default.
• W4328111523 cites W2802221596 @default.
• W4328111523 cites W2891935263 @default.
• W4328111523 cites W2970683859 @default.
• W4328111523 cites W2976035582 @default.
• W4328111523 cites W3036786163 @default.
• W4328111523 cites W3101867353 @default.
• W4328111523 cites W3196265097 @default.
• W4328111523 cites W4229013137 @default.
• W4328111523 doi "https://doi.org/10.2147/copd.s386518" @default.
• W4328111523 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36974273" @default.
• W4328111523 hasPublicationYear "2023" @default.
• W4328111523 type Work @default.
• W4328111523 citedByCount "1" @default.
• W4328111523 countsByYear W43281115232023 @default.
• W4328111523 crossrefType "journal-article" @default.
• W4328111523 hasAuthorship W4328111523A5002472471 @default.
• W4328111523 hasAuthorship W4328111523A5005472788 @default.
• W4328111523 hasAuthorship W4328111523A5007573133 @default.
• W4328111523 hasAuthorship W4328111523A5022531645 @default.
• W4328111523 hasAuthorship W4328111523A5024242782 @default.
• W4328111523 hasAuthorship W4328111523A5030592903 @default.
• W4328111523 hasAuthorship W4328111523A5032444299 @default.
• W4328111523 hasAuthorship W4328111523A5035965494 @default.
• W4328111523 hasAuthorship W4328111523A5040875204 @default.
• W4328111523 hasAuthorship W4328111523A5042252779 @default.
• W4328111523 hasAuthorship W4328111523A5044771174 @default.
• W4328111523 hasAuthorship W4328111523A5050473424 @default.
• W4328111523 hasAuthorship W4328111523A5054989002 @default.
• W4328111523 hasAuthorship W4328111523A5057223769 @default.
• W4328111523 hasAuthorship W4328111523A5066021887 @default.
• W4328111523 hasAuthorship W4328111523A5066100458 @default.
• W4328111523 hasAuthorship W4328111523A5074608165 @default.
• W4328111523 hasAuthorship W4328111523A5077156587 @default.
• W4328111523 hasAuthorship W4328111523A5082017828 @default.
• W4328111523 hasAuthorship W4328111523A5087894282 @default.
• W4328111523 hasBestOaLocation W43281115231 @default.
• W4328111523 hasConcept C107130276 @default.
• W4328111523 hasConcept C126322002 @default.
• W4328111523 hasConcept C201903717 @default.
• W4328111523 hasConcept C207103383 @default.
• W4328111523 hasConcept C2776780178 @default.
• W4328111523 hasConcept C2777914695 @default.
• W4328111523 hasConcept C2780221984 @default.
• W4328111523 hasConcept C2781253189 @default.
• W4328111523 hasConcept C2908647359 @default.
• W4328111523 hasConcept C44249647 @default.
• W4328111523 hasConcept C501593827 @default.
• W4328111523 hasConcept C50382708 @default.
• W4328111523 hasConcept C71924100 @default.
• W4328111523 hasConcept C72563966 @default.
• W4328111523 hasConcept C86803240 @default.
• W4328111523 hasConcept C89423630 @default.
• W4328111523 hasConcept C99454951 @default.
• W4328111523 hasConceptScore W4328111523C107130276 @default.
• W4328111523 hasConceptScore W4328111523C126322002 @default.
• W4328111523 hasConceptScore W4328111523C201903717 @default.
• W4328111523 hasConceptScore W4328111523C207103383 @default.
• W4328111523 hasConceptScore W4328111523C2776780178 @default.
• W4328111523 hasConceptScore W4328111523C2777914695 @default.
• W4328111523 hasConceptScore W4328111523C2780221984 @default.
• W4328111523 hasConceptScore W4328111523C2781253189 @default.

• next