Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328112160> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W4328112160 abstract "Current first-line standard therapy for metastatic non-small cell lung cancer without driver mutations involves chemotherapy and immunotherapy combination. Prior to the advent of immune checkpoint inhibition, REVEL, a randomized phase III trial demonstrated improved progression-free and overall survival with ramucirumab and docetaxel (ram+doc) in patients who failed platinum-based first-line therapy. Long-term outcomes related to second-line ramucirumab and docetaxel after first-line immunotherapy exposure remain unknown. We analyzed outcomes for 35 patients from our center whom received ramucirumab and docetaxel following disease progression on chemotherapy and immunotherapy combination. Median progression-free survival among patients who received ram+doc after exposure to immunotherapy was 6.6 months (95% CI = 5.5 to 14.9 months; p<0.0001), and median overall survival was 20.9 months (95% CI = 13.4 months to infinity; p<0.0001). These outcomes suggest that there may a synergistic benefit to combining chemotherapy with anti-angiogenic therapy after immunotherapy exposure. Future analyses should be evaluated prospectively and among a larger patient subset." @default.
- W4328112160 created "2023-03-22" @default.
- W4328112160 creator A5007664694 @default.
- W4328112160 creator A5011092600 @default.
- W4328112160 creator A5018518584 @default.
- W4328112160 creator A5020695450 @default.
- W4328112160 creator A5037593731 @default.
- W4328112160 creator A5041973184 @default.
- W4328112160 creator A5068401391 @default.
- W4328112160 date "2023-03-21" @default.
- W4328112160 modified "2023-10-18" @default.
- W4328112160 title "Efficacy and outcomes of ramucirumab and docetaxel in patients with metastatic non-small cell lung cancer after disease progression on immune checkpoint inhibitor therapy: Results of a monocentric, retrospective analysis" @default.
- W4328112160 cites W1839238860 @default.
- W4328112160 cites W2054841768 @default.
- W4328112160 cites W2111237964 @default.
- W4328112160 cites W2140980839 @default.
- W4328112160 cites W2170030318 @default.
- W4328112160 cites W2279027181 @default.
- W4328112160 cites W2289652418 @default.
- W4328112160 cites W2805354595 @default.
- W4328112160 cites W2892640821 @default.
- W4328112160 cites W2973186521 @default.
- W4328112160 cites W2982865643 @default.
- W4328112160 cites W3019468486 @default.
- W4328112160 cites W3102619725 @default.
- W4328112160 cites W3180979108 @default.
- W4328112160 cites W3186449511 @default.
- W4328112160 cites W4205320263 @default.
- W4328112160 cites W4225511749 @default.
- W4328112160 cites W4234236664 @default.
- W4328112160 cites W4281721227 @default.
- W4328112160 doi "https://doi.org/10.3389/fonc.2023.1012783" @default.
- W4328112160 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37025595" @default.
- W4328112160 hasPublicationYear "2023" @default.
- W4328112160 type Work @default.
- W4328112160 citedByCount "0" @default.
- W4328112160 crossrefType "journal-article" @default.
- W4328112160 hasAuthorship W4328112160A5007664694 @default.
- W4328112160 hasAuthorship W4328112160A5011092600 @default.
- W4328112160 hasAuthorship W4328112160A5018518584 @default.
- W4328112160 hasAuthorship W4328112160A5020695450 @default.
- W4328112160 hasAuthorship W4328112160A5037593731 @default.
- W4328112160 hasAuthorship W4328112160A5041973184 @default.
- W4328112160 hasAuthorship W4328112160A5068401391 @default.
- W4328112160 hasBestOaLocation W43281121601 @default.
- W4328112160 hasConcept C121608353 @default.
- W4328112160 hasConcept C126322002 @default.
- W4328112160 hasConcept C143998085 @default.
- W4328112160 hasConcept C2776256026 @default.
- W4328112160 hasConcept C2776694085 @default.
- W4328112160 hasConcept C2777701055 @default.
- W4328112160 hasConcept C2779551604 @default.
- W4328112160 hasConcept C2780030458 @default.
- W4328112160 hasConcept C2780739268 @default.
- W4328112160 hasConcept C2781190966 @default.
- W4328112160 hasConcept C71924100 @default.
- W4328112160 hasConceptScore W4328112160C121608353 @default.
- W4328112160 hasConceptScore W4328112160C126322002 @default.
- W4328112160 hasConceptScore W4328112160C143998085 @default.
- W4328112160 hasConceptScore W4328112160C2776256026 @default.
- W4328112160 hasConceptScore W4328112160C2776694085 @default.
- W4328112160 hasConceptScore W4328112160C2777701055 @default.
- W4328112160 hasConceptScore W4328112160C2779551604 @default.
- W4328112160 hasConceptScore W4328112160C2780030458 @default.
- W4328112160 hasConceptScore W4328112160C2780739268 @default.
- W4328112160 hasConceptScore W4328112160C2781190966 @default.
- W4328112160 hasConceptScore W4328112160C71924100 @default.
- W4328112160 hasLocation W43281121601 @default.
- W4328112160 hasLocation W43281121602 @default.
- W4328112160 hasLocation W43281121603 @default.
- W4328112160 hasOpenAccess W4328112160 @default.
- W4328112160 hasPrimaryLocation W43281121601 @default.
- W4328112160 hasRelatedWork W2301488980 @default.
- W4328112160 hasRelatedWork W2530066279 @default.
- W4328112160 hasRelatedWork W2766624957 @default.
- W4328112160 hasRelatedWork W2917630208 @default.
- W4328112160 hasRelatedWork W2922643990 @default.
- W4328112160 hasRelatedWork W2945823283 @default.
- W4328112160 hasRelatedWork W3020338344 @default.
- W4328112160 hasRelatedWork W3136984573 @default.
- W4328112160 hasRelatedWork W4328112160 @default.
- W4328112160 hasRelatedWork W4381162606 @default.
- W4328112160 hasVolume "13" @default.
- W4328112160 isParatext "false" @default.
- W4328112160 isRetracted "false" @default.
- W4328112160 workType "article" @default.