Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328114936> ?p ?o ?g. }
- W4328114936 abstract "Stroke, a serious systemic inflammatory disease, features neurological deficits and cardiovascular dysfunction. Neuroinflammation is characterized by the activation of microglia after stroke, which disrupts the cardiovascular-related neural network and the blood-brain barrier. Neural networks activate the autonomic nervous system to regulate the cardiac and blood vessels. Increased permeability of the blood-brain barrier and the lymphatic pathways promote the transfer of the central immune components to the peripheral immune organs and the recruitment of specific immune cells or cytokines, produced by the peripheral immune system, and thus modulate microglia in the brain. In addition, the spleen will also be stimulated by central inflammation to further mobilize the peripheral immune system. Both NK cells and Treg cells will be generated to enter the central nervous system to suppress further inflammation, while activated monocytes infiltrate the myocardium and cause cardiovascular dysfunction. In this review, we will focus on microglia-mediated inflammation in neural networks that result in cardiovascular dysfunction. Furthermore, we will discuss neuroimmune regulation in the central-peripheral crosstalk, in which the spleen is a vital part. Hopefully, this will benefit in anchoring another therapeutic target for neuro-cardiovascular dysfunction." @default.
- W4328114936 created "2023-03-22" @default.
- W4328114936 creator A5001719513 @default.
- W4328114936 creator A5014526810 @default.
- W4328114936 creator A5017611061 @default.
- W4328114936 creator A5031574239 @default.
- W4328114936 creator A5042241049 @default.
- W4328114936 creator A5065549183 @default.
- W4328114936 creator A5076623558 @default.
- W4328114936 date "2023-03-21" @default.
- W4328114936 modified "2023-09-26" @default.
- W4328114936 title "Microglia-mediated inflammatory destruction of neuro-cardiovascular dysfunction after stroke" @default.
- W4328114936 cites W1507819876 @default.
- W4328114936 cites W1818081481 @default.
- W4328114936 cites W1942368010 @default.
- W4328114936 cites W1950515180 @default.
- W4328114936 cites W1966194847 @default.
- W4328114936 cites W1981160000 @default.
- W4328114936 cites W1985983452 @default.
- W4328114936 cites W1986677588 @default.
- W4328114936 cites W1994363249 @default.
- W4328114936 cites W2001575728 @default.
- W4328114936 cites W2007143131 @default.
- W4328114936 cites W2018131256 @default.
- W4328114936 cites W2029051866 @default.
- W4328114936 cites W2047977029 @default.
- W4328114936 cites W2066908615 @default.
- W4328114936 cites W2074959430 @default.
- W4328114936 cites W2083816573 @default.
- W4328114936 cites W2084147470 @default.
- W4328114936 cites W2084833185 @default.
- W4328114936 cites W2090948638 @default.
- W4328114936 cites W2093416386 @default.
- W4328114936 cites W2110566966 @default.
- W4328114936 cites W2116505148 @default.
- W4328114936 cites W2123708489 @default.
- W4328114936 cites W2124836944 @default.
- W4328114936 cites W2130412168 @default.
- W4328114936 cites W2137827290 @default.
- W4328114936 cites W2139530080 @default.
- W4328114936 cites W2150105859 @default.
- W4328114936 cites W2159392834 @default.
- W4328114936 cites W2163526866 @default.
- W4328114936 cites W2163562064 @default.
- W4328114936 cites W2294323122 @default.
- W4328114936 cites W2299383924 @default.
- W4328114936 cites W2322853490 @default.
- W4328114936 cites W2346795597 @default.
- W4328114936 cites W2379226357 @default.
- W4328114936 cites W2525313139 @default.
- W4328114936 cites W2566147709 @default.
- W4328114936 cites W2586550193 @default.
- W4328114936 cites W2597009931 @default.
- W4328114936 cites W2613217394 @default.
- W4328114936 cites W2735325517 @default.
- W4328114936 cites W2744278888 @default.
- W4328114936 cites W2760038100 @default.
- W4328114936 cites W2792308671 @default.
- W4328114936 cites W2792452770 @default.
- W4328114936 cites W2804463010 @default.
- W4328114936 cites W2808497682 @default.
- W4328114936 cites W2883120089 @default.
- W4328114936 cites W2883766905 @default.
- W4328114936 cites W2895430781 @default.
- W4328114936 cites W2898965529 @default.
- W4328114936 cites W2901393645 @default.
- W4328114936 cites W2901550674 @default.
- W4328114936 cites W2938116464 @default.
- W4328114936 cites W2945808564 @default.
- W4328114936 cites W2947432394 @default.
- W4328114936 cites W2975911173 @default.
- W4328114936 cites W2979481873 @default.
- W4328114936 cites W2993450133 @default.
- W4328114936 cites W3002722566 @default.
- W4328114936 cites W3005719114 @default.
- W4328114936 cites W3020268755 @default.
- W4328114936 cites W3090010313 @default.
- W4328114936 cites W3114270534 @default.
- W4328114936 cites W3124365686 @default.
- W4328114936 cites W3126743392 @default.
- W4328114936 cites W3160456488 @default.
- W4328114936 cites W3162613988 @default.
- W4328114936 cites W3174186540 @default.
- W4328114936 cites W3203095985 @default.
- W4328114936 cites W3213904690 @default.
- W4328114936 cites W3215604156 @default.
- W4328114936 cites W4211247746 @default.
- W4328114936 cites W4281395882 @default.
- W4328114936 cites W4281778594 @default.
- W4328114936 doi "https://doi.org/10.3389/fncel.2023.1117218" @default.
- W4328114936 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37025698" @default.
- W4328114936 hasPublicationYear "2023" @default.
- W4328114936 type Work @default.
- W4328114936 citedByCount "0" @default.
- W4328114936 crossrefType "journal-article" @default.
- W4328114936 hasAuthorship W4328114936A5001719513 @default.
- W4328114936 hasAuthorship W4328114936A5014526810 @default.
- W4328114936 hasAuthorship W4328114936A5017611061 @default.
- W4328114936 hasAuthorship W4328114936A5031574239 @default.
- W4328114936 hasAuthorship W4328114936A5042241049 @default.