FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328115612> ?p ?o ?g. }

• W4328115612 abstract "Introduction Some patients with primary focal segmental sclerosis (FSGS) demonstrate complement 3 (C3) deposition in glomerular capillary loops (Cap-C3) and/or mesangial area (Mes-C3). The clinicopathological and prognostic significance of C3 deposition remains incompletely investigated, especially in the pediatric cohort. Methods We retrospectively analyzed 264 children of biopsy-proven primary FSGS between January 2003 and December 2020. The correlation between Cap-C3 and renal outcome was evaluated by the Kaplan-Meier method and Cox multivariate regression analysis. Renal end-point event was defined as the development of end-stage renal disease, death for renal disease, or an estimated glomerular filtration rate reduction by at least 50% from baseline. Results Among the 264 patients, 30 (11.4%) had Cap-C3. Kaplan-Meier analysis showed that patients with Cap-C3 had significantly lower renal survival rates than patients without Cap-C3 (60.17% vs. 84.71% at 5 years, 39.49% vs. 65.55% at 10 years, P &lt; 0.01). Cox multivariate regression analysis showed that Cap-C3 was an independent risk factor for poor renal outcome (HR 3.53, 95% CI 1.22–10.19, P = 0.02). Conclusion Glomerular capillary C3 deposition was an independent risk factor for unfavorable renal outcome in children with primary FSGS." @default.
• W4328115612 created "2023-03-22" @default.
• W4328115612 creator A5003017663 @default.
• W4328115612 creator A5011468070 @default.
• W4328115612 creator A5018805094 @default.
• W4328115612 creator A5022167006 @default.
• W4328115612 creator A5028740131 @default.
• W4328115612 creator A5033830330 @default.
• W4328115612 creator A5038394476 @default.
• W4328115612 creator A5047371223 @default.
• W4328115612 creator A5048733688 @default.
• W4328115612 creator A5055630500 @default.
• W4328115612 creator A5067869362 @default.
• W4328115612 creator A5068713962 @default.
• W4328115612 creator A5086365614 @default.
• W4328115612 date "2023-03-21" @default.
• W4328115612 modified "2023-09-27" @default.
• W4328115612 title "Glomerular capillary C3 deposition as a risk factor for unfavorable renal outcome in pediatric primary focal segmental glomerular sclerosis" @default.
• W4328115612 cites W1525077726 @default.
• W4328115612 cites W1561068209 @default.
• W4328115612 cites W1663880144 @default.
• W4328115612 cites W1865928485 @default.
• W4328115612 cites W1894886495 @default.
• W4328115612 cites W2000637899 @default.
• W4328115612 cites W2103803344 @default.
• W4328115612 cites W2126021594 @default.
• W4328115612 cites W2145361806 @default.
• W4328115612 cites W2146684857 @default.
• W4328115612 cites W2163543028 @default.
• W4328115612 cites W2164060244 @default.
• W4328115612 cites W2286127041 @default.
• W4328115612 cites W2468199092 @default.
• W4328115612 cites W2554519074 @default.
• W4328115612 cites W2624798972 @default.
• W4328115612 cites W2735587348 @default.
• W4328115612 cites W2750645879 @default.
• W4328115612 cites W2766700018 @default.
• W4328115612 cites W2800928182 @default.
• W4328115612 cites W2910319185 @default.
• W4328115612 cites W2969895713 @default.
• W4328115612 cites W3021746826 @default.
• W4328115612 cites W3035891079 @default.
• W4328115612 cites W3090924316 @default.
• W4328115612 cites W3197065228 @default.
• W4328115612 cites W4306926009 @default.
• W4328115612 doi "https://doi.org/10.3389/fped.2023.1137375" @default.
• W4328115612 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37025292" @default.
• W4328115612 hasPublicationYear "2023" @default.
• W4328115612 type Work @default.
• W4328115612 citedByCount "0" @default.
• W4328115612 crossrefType "journal-article" @default.
• W4328115612 hasAuthorship W4328115612A5003017663 @default.
• W4328115612 hasAuthorship W4328115612A5011468070 @default.
• W4328115612 hasAuthorship W4328115612A5018805094 @default.
• W4328115612 hasAuthorship W4328115612A5022167006 @default.
• W4328115612 hasAuthorship W4328115612A5028740131 @default.
• W4328115612 hasAuthorship W4328115612A5033830330 @default.
• W4328115612 hasAuthorship W4328115612A5038394476 @default.
• W4328115612 hasAuthorship W4328115612A5047371223 @default.
• W4328115612 hasAuthorship W4328115612A5048733688 @default.
• W4328115612 hasAuthorship W4328115612A5055630500 @default.
• W4328115612 hasAuthorship W4328115612A5067869362 @default.
• W4328115612 hasAuthorship W4328115612A5068713962 @default.
• W4328115612 hasAuthorship W4328115612A5086365614 @default.
• W4328115612 hasBestOaLocation W43281156121 @default.
• W4328115612 hasConcept C126322002 @default.
• W4328115612 hasConcept C126894567 @default.
• W4328115612 hasConcept C159641895 @default.
• W4328115612 hasConcept C2778653478 @default.
• W4328115612 hasConcept C38180746 @default.
• W4328115612 hasConcept C50382708 @default.
• W4328115612 hasConcept C50440223 @default.
• W4328115612 hasConcept C71924100 @default.
• W4328115612 hasConcept C90924648 @default.
• W4328115612 hasConceptScore W4328115612C126322002 @default.
• W4328115612 hasConceptScore W4328115612C126894567 @default.
• W4328115612 hasConceptScore W4328115612C159641895 @default.
• W4328115612 hasConceptScore W4328115612C2778653478 @default.
• W4328115612 hasConceptScore W4328115612C38180746 @default.
• W4328115612 hasConceptScore W4328115612C50382708 @default.
• W4328115612 hasConceptScore W4328115612C50440223 @default.
• W4328115612 hasConceptScore W4328115612C71924100 @default.
• W4328115612 hasConceptScore W4328115612C90924648 @default.
• W4328115612 hasLocation W43281156121 @default.
• W4328115612 hasLocation W43281156122 @default.
• W4328115612 hasLocation W43281156123 @default.
• W4328115612 hasOpenAccess W4328115612 @default.
• W4328115612 hasPrimaryLocation W43281156121 @default.
• W4328115612 hasRelatedWork W2105019708 @default.
• W4328115612 hasRelatedWork W2119284279 @default.
• W4328115612 hasRelatedWork W2124543160 @default.
• W4328115612 hasRelatedWork W2127399187 @default.
• W4328115612 hasRelatedWork W2144546995 @default.
• W4328115612 hasRelatedWork W2532864188 @default.
• W4328115612 hasRelatedWork W2889082092 @default.
• W4328115612 hasRelatedWork W3011378569 @default.
• W4328115612 hasRelatedWork W4280508227 @default.
• W4328115612 hasRelatedWork W4323255495 @default.
• W4328115612 hasVolume "11" @default.
• W4328115612 isParatext "false" @default.

• next