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- W4328123491 endingPage "952" @default.
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- W4328123491 abstract "Epigenetic remodeling and metabolic reprogramming, two well-known cancer hallmarks, are highly intertwined. In addition to their abilities to confer cancer cell growth advantage, these alterations play a critical role in dynamically shaping the tumor microenvironment and antitumor immunity. Recent studies point toward the interplay between epigenetic regulation and metabolic rewiring as a potentially targetable Achilles' heel in cancer. In this review, we explore the key metabolic mechanisms that underpin the immunomodulatory role of AT-rich interaction domain 1A (ARID1A), the most frequently mutated epigenetic regulator across human cancers. We will summarize the recent advances in targeting ARID1A-deficient cancers by harnessing immune-metabolic vulnerability elicited by ARID1A deficiency to stimulate antitumor immune response, and ultimately, to improve patient outcome." @default.
- W4328123491 created "2023-03-22" @default.
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- W4328123491 creator A5041996159 @default.
- W4328123491 date "2023-03-21" @default.
- W4328123491 modified "2023-10-14" @default.
- W4328123491 title "Targeting ARID1A-Deficient Cancers: An Immune-Metabolic Perspective" @default.
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- W4328123491 cites W2067826589 @default.
- W4328123491 cites W2068127752 @default.
- W4328123491 cites W2071168599 @default.
- W4328123491 cites W2086775982 @default.
- W4328123491 cites W2096489607 @default.
- W4328123491 cites W2112612051 @default.
- W4328123491 cites W2112728955 @default.
- W4328123491 cites W2123454509 @default.
- W4328123491 cites W2124652061 @default.
- W4328123491 cites W2271706140 @default.
- W4328123491 cites W2279299471 @default.
- W4328123491 cites W2463557454 @default.
- W4328123491 cites W2563490856 @default.
- W4328123491 cites W2738156861 @default.
- W4328123491 cites W2739511077 @default.
- W4328123491 cites W2770519623 @default.
- W4328123491 cites W2794761110 @default.
- W4328123491 cites W2802645166 @default.
- W4328123491 cites W2805660084 @default.
- W4328123491 cites W2897810065 @default.
- W4328123491 cites W2899145148 @default.
- W4328123491 cites W2912580313 @default.
- W4328123491 cites W2921552181 @default.
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- W4328123491 doi "https://doi.org/10.3390/cells12060952" @default.
- W4328123491 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36980292" @default.
- W4328123491 hasPublicationYear "2023" @default.
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