Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328124769> ?p ?o ?g. }
- W4328124769 endingPage "1384" @default.
- W4328124769 startingPage "1384" @default.
- W4328124769 abstract "The SHPRH (SNF2, histone linker, PHD, RING, helicase) subfamily belonging to ATP-dependent chromatin remodeling factor is the effective tumor-suppressor, which can polyubiquitinate PCNA (proliferating cell nuclear antigen) and participate in post-replication repair in human. However, little is known about the functions of SHPRH proteins in plants. In this study, we identified a novel SHPRH member BrCHR39 and obtained BrCHR39-silenced transgenic Brassica rapa. In contrast to wild-type plants, transgenic Brassica plants exhibited a released apical dominance phenotype with semi-dwarfism and multiple lateral branches. Furthermore, a global alteration of DNA methylation in the main stem and bud appeared after silencing of BrCHR39. Based on the GO (gene ontology) functional annotation and KEGG (Kyoto encyclopedia of genes and genomes) pathway analysis, the plant hormone signal transduction pathway was clearly enriched. In particular, we found a significant increase in the methylation level of auxin-related genes in the stem, whereas auxin- and cytokinin-related genes were hypomethylated in the bud of transgenic plants. In addition, further qRT-PCR (quantitative real-time PCR) analysis revealed that DNA methylation level always had an opposite trend with gene expression level. Considered together, our findings indicated that suppression of BrCHR39 expression triggered the methylation divergence of hormone-related genes and subsequently affected transcription levels to regulate the apical dominance in Brassica rapa." @default.
- W4328124769 created "2023-03-22" @default.
- W4328124769 creator A5001310615 @default.
- W4328124769 creator A5016832353 @default.
- W4328124769 creator A5018574040 @default.
- W4328124769 creator A5026807143 @default.
- W4328124769 creator A5028455946 @default.
- W4328124769 creator A5034246486 @default.
- W4328124769 creator A5039819599 @default.
- W4328124769 creator A5060458647 @default.
- W4328124769 creator A5072909687 @default.
- W4328124769 creator A5091468045 @default.
- W4328124769 date "2023-03-20" @default.
- W4328124769 modified "2023-09-26" @default.
- W4328124769 title "The Chromatin Remodeling Factor BrCHR39 Targets DNA Methylation to Positively Regulate Apical Dominance in Brassica rapa" @default.
- W4328124769 cites W1481026422 @default.
- W4328124769 cites W1486257535 @default.
- W4328124769 cites W1500702901 @default.
- W4328124769 cites W1935113814 @default.
- W4328124769 cites W1971635495 @default.
- W4328124769 cites W1971845731 @default.
- W4328124769 cites W1974964336 @default.
- W4328124769 cites W1978143022 @default.
- W4328124769 cites W1984394794 @default.
- W4328124769 cites W1984891757 @default.
- W4328124769 cites W1990053450 @default.
- W4328124769 cites W1997616948 @default.
- W4328124769 cites W2000199388 @default.
- W4328124769 cites W2014819523 @default.
- W4328124769 cites W2052619501 @default.
- W4328124769 cites W2055980504 @default.
- W4328124769 cites W2058506354 @default.
- W4328124769 cites W2059979506 @default.
- W4328124769 cites W2061434854 @default.
- W4328124769 cites W2064075421 @default.
- W4328124769 cites W2077782352 @default.
- W4328124769 cites W2082960726 @default.
- W4328124769 cites W2092937197 @default.
- W4328124769 cites W2093931964 @default.
- W4328124769 cites W2098574932 @default.
- W4328124769 cites W2107277218 @default.
- W4328124769 cites W2116910117 @default.
- W4328124769 cites W2118342658 @default.
- W4328124769 cites W2119517364 @default.
- W4328124769 cites W2123921804 @default.
- W4328124769 cites W2133452708 @default.
- W4328124769 cites W2136623765 @default.
- W4328124769 cites W2141991853 @default.
- W4328124769 cites W2145699080 @default.
- W4328124769 cites W2149685146 @default.
- W4328124769 cites W2152642144 @default.
- W4328124769 cites W2157104689 @default.
- W4328124769 cites W2192080449 @default.
- W4328124769 cites W2194548253 @default.
- W4328124769 cites W2285122823 @default.
- W4328124769 cites W2471551755 @default.
- W4328124769 cites W2494121918 @default.
- W4328124769 cites W2560535232 @default.
- W4328124769 cites W2592817720 @default.
- W4328124769 cites W2607108415 @default.
- W4328124769 cites W2620463298 @default.
- W4328124769 cites W2766265681 @default.
- W4328124769 cites W2769907914 @default.
- W4328124769 cites W2803407896 @default.
- W4328124769 cites W2804344327 @default.
- W4328124769 cites W2804369390 @default.
- W4328124769 cites W2888533093 @default.
- W4328124769 cites W2891815199 @default.
- W4328124769 cites W2898730423 @default.
- W4328124769 cites W2918022706 @default.
- W4328124769 cites W2950103832 @default.
- W4328124769 cites W2963311394 @default.
- W4328124769 cites W2967268756 @default.
- W4328124769 cites W2969837683 @default.
- W4328124769 cites W2969875740 @default.
- W4328124769 cites W297814484 @default.
- W4328124769 cites W3014471916 @default.
- W4328124769 cites W3095835535 @default.
- W4328124769 cites W3101335101 @default.
- W4328124769 cites W3164684535 @default.
- W4328124769 cites W3202567534 @default.
- W4328124769 cites W3216631499 @default.
- W4328124769 cites W4200492236 @default.
- W4328124769 cites W4212868987 @default.
- W4328124769 cites W4220755561 @default.
- W4328124769 cites W4288067171 @default.
- W4328124769 cites W4311279851 @default.
- W4328124769 doi "https://doi.org/10.3390/plants12061384" @default.
- W4328124769 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36987072" @default.
- W4328124769 hasPublicationYear "2023" @default.
- W4328124769 type Work @default.
- W4328124769 citedByCount "0" @default.
- W4328124769 crossrefType "journal-article" @default.
- W4328124769 hasAuthorship W4328124769A5001310615 @default.
- W4328124769 hasAuthorship W4328124769A5016832353 @default.
- W4328124769 hasAuthorship W4328124769A5018574040 @default.
- W4328124769 hasAuthorship W4328124769A5026807143 @default.
- W4328124769 hasAuthorship W4328124769A5028455946 @default.