FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328130285> ?p ?o ?g. }

• W4328130285 abstract "Abstract Purpose The study aimed to investigate the adverse effects of long-term aflibercept injections on the lesion-free retina in eyes with neovascular age-related macular degeneration (nAMD). Methods This retrospective, comparative study consisted of aflibercept-injected 48 eyes diagnosed with nAMD, treatment-naive 42 nAMD eyes, and 40 eyes with drusen in the control group. The measurements were done with spectral-domain optical coherence tomography. The center of the Early Treatment Diabetic Retinopathy Study (ETDRS) grid was centered at a 3-mm distance from the foveola temporally. Total retinal thickness and the thicknesses of each retinal layer in the outer temporal subfield of the ETDRS grid were measured separately. One-way ANOVA test for normally distributed variables was applied for analyses of differences for the comparison of the results between groups. A p-value of less than 0.05 was considered statistically significant. Results The median follow-up time was 51.35 ± 20.92 months. Retinal nerve fiber layer thickness (RNFL) was highest in the treated nAMD group, followed by the treatment-naive nAMD and drusen groups. However, the difference between the treated nAMD and drusen groups showed statistical significance (17.77 ± 2.57 µm; 16.15 ± 1.81 µm, p < 0.05). Total retina, ganglion cell layer, inner plexiform layer, inner nuclear layer, outer plexiform layer, outer nuclear layer, and retina pigment epithelium thicknesses didn’t show a statistically significant difference between the groups (p > 0.05). Conclusions The study demonstrated an increase in RNFL thickness in the lesion-free retina after long-term aflibercept treatments. This finding may suggest the expansion of AMD pathology to the normal-appearing retina rather than the aflibercept effect." @default.
• W4328130285 created "2023-03-22" @default.
• W4328130285 creator A5011385420 @default.
• W4328130285 creator A5019860619 @default.
• W4328130285 creator A5026567565 @default.
• W4328130285 creator A5034954249 @default.
• W4328130285 date "2023-03-21" @default.
• W4328130285 modified "2023-09-25" @default.
• W4328130285 title "Long-Term Effects of Aflibercept Injections on Lesion-Free Retina in Eyes with Neovascular Age-Related Macular Degeneration" @default.
• W4328130285 cites W1584037566 @default.
• W4328130285 cites W1691809782 @default.
• W4328130285 cites W1996586806 @default.
• W4328130285 cites W2017216724 @default.
• W4328130285 cites W2040498221 @default.
• W4328130285 cites W2042904305 @default.
• W4328130285 cites W2051694831 @default.
• W4328130285 cites W2067626374 @default.
• W4328130285 cites W2070890840 @default.
• W4328130285 cites W2071136620 @default.
• W4328130285 cites W2076151830 @default.
• W4328130285 cites W2079397885 @default.
• W4328130285 cites W2106466837 @default.
• W4328130285 cites W2123992786 @default.
• W4328130285 cites W2150414697 @default.
• W4328130285 cites W2153581036 @default.
• W4328130285 cites W2159764938 @default.
• W4328130285 cites W2335849236 @default.
• W4328130285 cites W2345096045 @default.
• W4328130285 cites W2594022992 @default.
• W4328130285 cites W2732639529 @default.
• W4328130285 cites W2897522670 @default.
• W4328130285 cites W2996581425 @default.
• W4328130285 cites W3011074174 @default.
• W4328130285 cites W3081331592 @default.
• W4328130285 cites W3091804993 @default.
• W4328130285 cites W3159132790 @default.
• W4328130285 doi "https://doi.org/10.21203/rs.3.rs-2693194/v1" @default.
• W4328130285 hasPublicationYear "2023" @default.
• W4328130285 type Work @default.
• W4328130285 citedByCount "0" @default.
• W4328130285 crossrefType "posted-content" @default.
• W4328130285 hasAuthorship W4328130285A5011385420 @default.
• W4328130285 hasAuthorship W4328130285A5019860619 @default.
• W4328130285 hasAuthorship W4328130285A5026567565 @default.
• W4328130285 hasAuthorship W4328130285A5034954249 @default.
• W4328130285 hasBestOaLocation W43281302851 @default.
• W4328130285 hasConcept C118487528 @default.
• W4328130285 hasConcept C134018914 @default.
• W4328130285 hasConcept C141071460 @default.
• W4328130285 hasConcept C15744967 @default.
• W4328130285 hasConcept C169760540 @default.
• W4328130285 hasConcept C2776403814 @default.
• W4328130285 hasConcept C2776694085 @default.
• W4328130285 hasConcept C2777093970 @default.
• W4328130285 hasConcept C2777506830 @default.
• W4328130285 hasConcept C2777802072 @default.
• W4328130285 hasConcept C2778231335 @default.
• W4328130285 hasConcept C2778749236 @default.
• W4328130285 hasConcept C2778818243 @default.
• W4328130285 hasConcept C2779093074 @default.
• W4328130285 hasConcept C2779736970 @default.
• W4328130285 hasConcept C2779829184 @default.
• W4328130285 hasConcept C2780188069 @default.
• W4328130285 hasConcept C2780592520 @default.
• W4328130285 hasConcept C2780827179 @default.
• W4328130285 hasConcept C2781099447 @default.
• W4328130285 hasConcept C2781156865 @default.
• W4328130285 hasConcept C30181142 @default.
• W4328130285 hasConcept C555293320 @default.
• W4328130285 hasConcept C71924100 @default.
• W4328130285 hasConceptScore W4328130285C118487528 @default.
• W4328130285 hasConceptScore W4328130285C134018914 @default.
• W4328130285 hasConceptScore W4328130285C141071460 @default.
• W4328130285 hasConceptScore W4328130285C15744967 @default.
• W4328130285 hasConceptScore W4328130285C169760540 @default.
• W4328130285 hasConceptScore W4328130285C2776403814 @default.
• W4328130285 hasConceptScore W4328130285C2776694085 @default.
• W4328130285 hasConceptScore W4328130285C2777093970 @default.
• W4328130285 hasConceptScore W4328130285C2777506830 @default.
• W4328130285 hasConceptScore W4328130285C2777802072 @default.
• W4328130285 hasConceptScore W4328130285C2778231335 @default.
• W4328130285 hasConceptScore W4328130285C2778749236 @default.
• W4328130285 hasConceptScore W4328130285C2778818243 @default.
• W4328130285 hasConceptScore W4328130285C2779093074 @default.
• W4328130285 hasConceptScore W4328130285C2779736970 @default.
• W4328130285 hasConceptScore W4328130285C2779829184 @default.
• W4328130285 hasConceptScore W4328130285C2780188069 @default.
• W4328130285 hasConceptScore W4328130285C2780592520 @default.
• W4328130285 hasConceptScore W4328130285C2780827179 @default.
• W4328130285 hasConceptScore W4328130285C2781099447 @default.
• W4328130285 hasConceptScore W4328130285C2781156865 @default.
• W4328130285 hasConceptScore W4328130285C30181142 @default.
• W4328130285 hasConceptScore W4328130285C555293320 @default.
• W4328130285 hasConceptScore W4328130285C71924100 @default.
• W4328130285 hasLocation W43281302851 @default.
• W4328130285 hasOpenAccess W4328130285 @default.
• W4328130285 hasPrimaryLocation W43281302851 @default.
• W4328130285 hasRelatedWork W2007292127 @default.
• W4328130285 hasRelatedWork W2008140687 @default.
• W4328130285 hasRelatedWork W2029580475 @default.

• next