FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328134662> ?p ?o ?g. }

• W4328134662 abstract "Abstract Introduction Prediabetes is an intermediate state of progression from normoglycemia to overt type 2 diabetes. Literature suggests that managing prediabetes is beneficial in delaying the onset of diabetes. Previous studies have shown that Momordica balsamina (MB) possesses anti-hyperglycaemic effects; hence in this study, its effect on renal function in diet-induced pre-diabetes was explored. Methodology Male Sprague-Dawley rats (130-180 g) were divided into six groups of six rats per group; Normal control, Prediabetic (PD), Metformin (500 mg/kg, p.o.) treated PD without dietary intervention (DI), MB (250 mg/kg, p.o.) treated PD without DI, Metformin treated PD with DI and MB treated PD with DI. The animals were treated for 12 weeks of the last 32 weeks where fluid intake and urinary output was measured. After 12 weeks, the animals were sacrificed, plasma, urine, and kidney samples were collected for biochemical analysis. Results The untreated prediabetic (PD) rats presented with increased fluid intake and urine output; increased creatinine, urea, and uric acid plasma concentrations; sodium retention; potassium loss; increased aldosterone and kidney injury molecule (KIM-1) concentration; and increased urinary podocin mRNA concentration. However, MB administration attenuated the renal markers and oxidative stress and decreased the urinary podocin mRNA expression with or without diet intervention. Conclusion MB administration, regardless of diet modification, attenuates renal dysfunction in an experimentally induced prediabetic state. This suggests that MB has beneficial properties in the management of pre-diabetes associated kidney dysfunction." @default.
• W4328134662 created "2023-03-22" @default.
• W4328134662 creator A5015066210 @default.
• W4328134662 creator A5015290575 @default.
• W4328134662 creator A5024470731 @default.
• W4328134662 creator A5026933892 @default.
• W4328134662 creator A5077331751 @default.
• W4328134662 creator A5083343593 @default.
• W4328134662 date "2023-03-21" @default.
• W4328134662 modified "2023-09-27" @default.
• W4328134662 title "Effects of Momordica balsamina on markers associated with renal dysfunction in a diet-induced prediabetic rat model" @default.
• W4328134662 cites W1805630579 @default.
• W4328134662 cites W1964405385 @default.
• W4328134662 cites W1982687614 @default.
• W4328134662 cites W2007108460 @default.
• W4328134662 cites W2025914300 @default.
• W4328134662 cites W2055298026 @default.
• W4328134662 cites W2061172276 @default.
• W4328134662 cites W2064237729 @default.
• W4328134662 cites W2068281013 @default.
• W4328134662 cites W2075402732 @default.
• W4328134662 cites W2078060415 @default.
• W4328134662 cites W2095014092 @default.
• W4328134662 cites W2099974062 @default.
• W4328134662 cites W2100817694 @default.
• W4328134662 cites W2104865391 @default.
• W4328134662 cites W2114079106 @default.
• W4328134662 cites W2127454034 @default.
• W4328134662 cites W2137156703 @default.
• W4328134662 cites W2404356588 @default.
• W4328134662 cites W2421878187 @default.
• W4328134662 cites W2505652263 @default.
• W4328134662 cites W2538973672 @default.
• W4328134662 cites W2739639822 @default.
• W4328134662 cites W2797568927 @default.
• W4328134662 cites W2804044000 @default.
• W4328134662 cites W2902383554 @default.
• W4328134662 cites W2911720884 @default.
• W4328134662 cites W2971564284 @default.
• W4328134662 cites W2988431376 @default.
• W4328134662 cites W3005953879 @default.
• W4328134662 cites W3042192606 @default.
• W4328134662 cites W44929223 @default.
• W4328134662 doi "https://doi.org/10.21203/rs.3.rs-2701845/v1" @default.
• W4328134662 hasPublicationYear "2023" @default.
• W4328134662 type Work @default.
• W4328134662 citedByCount "0" @default.
• W4328134662 crossrefType "posted-content" @default.
• W4328134662 hasAuthorship W4328134662A5015066210 @default.
• W4328134662 hasAuthorship W4328134662A5015290575 @default.
• W4328134662 hasAuthorship W4328134662A5024470731 @default.
• W4328134662 hasAuthorship W4328134662A5026933892 @default.
• W4328134662 hasAuthorship W4328134662A5077331751 @default.
• W4328134662 hasAuthorship W4328134662A5083343593 @default.
• W4328134662 hasBestOaLocation W43281346621 @default.
• W4328134662 hasConcept C126322002 @default.
• W4328134662 hasConcept C134018914 @default.
• W4328134662 hasConcept C159641895 @default.
• W4328134662 hasConcept C2776855237 @default.
• W4328134662 hasConcept C2777146197 @default.
• W4328134662 hasConcept C2777180221 @default.
• W4328134662 hasConcept C2779561371 @default.
• W4328134662 hasConcept C2779668308 @default.
• W4328134662 hasConcept C2779881121 @default.
• W4328134662 hasConcept C2780026642 @default.
• W4328134662 hasConcept C2780091579 @default.
• W4328134662 hasConcept C2780306776 @default.
• W4328134662 hasConcept C2780323712 @default.
• W4328134662 hasConcept C2780609358 @default.
• W4328134662 hasConcept C555293320 @default.
• W4328134662 hasConcept C71924100 @default.
• W4328134662 hasConcept C77411442 @default.
• W4328134662 hasConceptScore W4328134662C126322002 @default.
• W4328134662 hasConceptScore W4328134662C134018914 @default.
• W4328134662 hasConceptScore W4328134662C159641895 @default.
• W4328134662 hasConceptScore W4328134662C2776855237 @default.
• W4328134662 hasConceptScore W4328134662C2777146197 @default.
• W4328134662 hasConceptScore W4328134662C2777180221 @default.
• W4328134662 hasConceptScore W4328134662C2779561371 @default.
• W4328134662 hasConceptScore W4328134662C2779668308 @default.
• W4328134662 hasConceptScore W4328134662C2779881121 @default.
• W4328134662 hasConceptScore W4328134662C2780026642 @default.
• W4328134662 hasConceptScore W4328134662C2780091579 @default.
• W4328134662 hasConceptScore W4328134662C2780306776 @default.
• W4328134662 hasConceptScore W4328134662C2780323712 @default.
• W4328134662 hasConceptScore W4328134662C2780609358 @default.
• W4328134662 hasConceptScore W4328134662C555293320 @default.
• W4328134662 hasConceptScore W4328134662C71924100 @default.
• W4328134662 hasConceptScore W4328134662C77411442 @default.
• W4328134662 hasLocation W43281346621 @default.
• W4328134662 hasOpenAccess W4328134662 @default.
• W4328134662 hasPrimaryLocation W43281346621 @default.
• W4328134662 hasRelatedWork W2057655956 @default.
• W4328134662 hasRelatedWork W2091638536 @default.
• W4328134662 hasRelatedWork W2116657465 @default.
• W4328134662 hasRelatedWork W2342072646 @default.
• W4328134662 hasRelatedWork W2769137505 @default.
• W4328134662 hasRelatedWork W293724581 @default.
• W4328134662 hasRelatedWork W3034163622 @default.
• W4328134662 hasRelatedWork W3117885438 @default.

• next