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• W4328136387 abstract "We thank Litaiem et al for their interest in our recent publication regarding cutaneous T-cell lymphoma (CTCL) and pregnancy.1LeWitt T.M. Walker C.J. Espinosa M.L. et al.Cutaneous T-cell lymphoma and pregnancy: great uncertainty and an appeal for prospective clinical research.J Am Acad Dermatol. 2022; 87: 856-858https://doi.org/10.1016/j.jaad.2021.10.041Abstract Full Text Full Text PDF PubMed Scopus (2) Google Scholar Due to the retrospective nature of our case series, we were often limited in our ability to characterize disease flares. We relied on objective data and photos from our electronic medical record and information provided by patients during phone interviews, of which the latter may be subject to recall bias. We concur with Litaiem et al, who recommend a more precise definition of disease flare for future studies, focused on the relationship between CTCL and pregnancy. Furthermore, we agree that methods, such as standardized photography, may be beneficial for future studies. Nevertheless, it is important to note that although defining flares is often helpful for staging and treatment purposes in nonpregnant patients, we continue to be limited by known or potential teratogenic effects of many standard therapies for CTCL. This holds true, irrespective of disease progression during pregnancy. We fully support future prospective multi-institutional studies that more objectively describe CTCL flares during pregnancy and propose the need for more skin-directed therapies that do not pose risk to the fetus. None disclosed. A need for a clear definition of mycosis fungoides flares to evaluate disease course during pregnancyJournal of the American Academy of DermatologyVol. 89Issue 1PreviewTo the Editor: We read with interest the article entitled “Cutaneous T-cell lymphoma and pregnancy: Great uncertainty and an appeal for prospective clinical research” by LeWitt et al.1 In this retrospective study, 37 pregnancies in 22 patients with cutaneous T-cell lymphoma were included, and 56.8% of patients reported worsening of their skin condition. Nine of 16 pregnant women with mycosis fungoides (MF) experienced disease flares mainly attributed to treatment discontinuation.1 Full-Text PDF" @default.
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• W4328136387 date "2023-07-01" @default.
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• W4328136387 title "Reply to letter to the editor (Manuscript # JAAD-D-22-03011R1)" @default.
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• W4328136387 doi "https://doi.org/10.1016/j.jaad.2023.02.056" @default.
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