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- W4328142845 startingPage "102304" @default.
- W4328142845 abstract "Helicobacter pylori is responsible for one of the most prevalent bacterial infections worldwide. Chronic infection typically leads to chronic active gastritis. Clinical sequelae, including peptic ulcers, mucosa-associated lymphoid tissue lymphoma or, most importantly, gastric adenocarcinoma develop in 10-15% of cases. H. pylori is characterized by extensive inter-strain diversity which is the result of a high mutation rate, recombination, and a large repertoire of restriction-modification systems. This diversity is thought to be a major contributor to H. pylori's persistence and exceptional aptitude to adapt to the gastric environment and evade the immune system. This review covers efforts in the last decade to characterize and understand the multiple layers of H. pylori's diversity in different biological contexts." @default.
- W4328142845 created "2023-03-22" @default.
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- W4328142845 date "2023-06-01" @default.
- W4328142845 modified "2023-10-06" @default.
- W4328142845 title "Genome and population dynamics during chronic infection with Helicobacter pylori" @default.
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- W4328142845 doi "https://doi.org/10.1016/j.coi.2023.102304" @default.
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