FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4328143758> ?p ?o ?g. }

• W4328143758 endingPage "984" @default.
• W4328143758 startingPage "974" @default.
• W4328143758 abstract "Widespread pain hypersensitivity and enhanced temporal summation of pain (TSP) are commonly reported in patients with complex regional pain syndrome (CRPS) and discussed as proxies for central sensitization. This study aimed to directly relate such signs of neuronal hyperexcitability to the pain phenotype of CRPS patients.Twenty-one CRPS patients and 20 healthy controls (HC) were recruited. The pain phenotype including spatial pain extent (assessed in % body surface) and intensity were assessed and related to widespread pain hypersensitivity, TSP, and psychological factors. Quantitative sensory testing (QST) was performed in the affected, the contralateral and a remote (control) area.CRPS patients showed decreased pressure pain thresholds in all tested areas (affected: t(34) = 4.98, P < .001, contralateral: t(35) = 3.19, P = .005, control: t(31) = 2.65, P = .012). Additionally, patients showed increased TSP in the affected area (F(3,111) = 4.57, P = .009) compared to HC. TSP was even more enhanced in patients with a high compared to a low spatial pain extent (F(3,51) = 5.67, P = .008), suggesting pronounced spinal sensitization in patients with extended pain patterns. Furthermore, the spatial pain extent positively correlated with the Bath Body Perception Disturbance Scale (ρ = 0.491; P = .048).Overall, we provide evidence that the pain phenotype in CRPS, that is, spatial pain extent, might be related to sensitization mechanism within the central nociceptive system. This study points towards central neuronal excitability as a potential therapeutic target in patients with more widespread CRPS." @default.
• W4328143758 created "2023-03-22" @default.
• W4328143758 creator A5012717312 @default.
• W4328143758 creator A5020251712 @default.
• W4328143758 creator A5032775119 @default.
• W4328143758 creator A5035220104 @default.
• W4328143758 creator A5064369545 @default.
• W4328143758 creator A5069598374 @default.
• W4328143758 creator A5076930866 @default.
• W4328143758 creator A5087223695 @default.
• W4328143758 creator A5091449737 @default.
• W4328143758 date "2023-03-22" @default.
• W4328143758 modified "2023-10-03" @default.
• W4328143758 title "Central sensitization in CRPS patients with widespread pain: a cross-sectional study" @default.
• W4328143758 cites W1845447069 @default.
• W4328143758 cites W1974125795 @default.
• W4328143758 cites W1980257272 @default.
• W4328143758 cites W1982210026 @default.
• W4328143758 cites W1989263623 @default.
• W4328143758 cites W1990126819 @default.
• W4328143758 cites W2004623168 @default.
• W4328143758 cites W2025513503 @default.
• W4328143758 cites W2031369455 @default.
• W4328143758 cites W2053342230 @default.
• W4328143758 cites W2054862674 @default.
• W4328143758 cites W2056885349 @default.
• W4328143758 cites W2063303321 @default.
• W4328143758 cites W2070673209 @default.
• W4328143758 cites W2071329829 @default.
• W4328143758 cites W2075715972 @default.
• W4328143758 cites W2087027636 @default.
• W4328143758 cites W2095387649 @default.
• W4328143758 cites W2099156550 @default.
• W4328143758 cites W2101473241 @default.
• W4328143758 cites W2108197576 @default.
• W4328143758 cites W2119099065 @default.
• W4328143758 cites W2122097870 @default.
• W4328143758 cites W2139927756 @default.
• W4328143758 cites W2141203994 @default.
• W4328143758 cites W2143077460 @default.
• W4328143758 cites W2147259464 @default.
• W4328143758 cites W2147812749 @default.
• W4328143758 cites W2166281097 @default.
• W4328143758 cites W2166318214 @default.
• W4328143758 cites W2176092399 @default.
• W4328143758 cites W2312672018 @default.
• W4328143758 cites W2319720537 @default.
• W4328143758 cites W2338302261 @default.
• W4328143758 cites W2346855238 @default.
• W4328143758 cites W2401204260 @default.
• W4328143758 cites W2405023198 @default.
• W4328143758 cites W2490582742 @default.
• W4328143758 cites W2519699745 @default.
• W4328143758 cites W2550011234 @default.
• W4328143758 cites W2583177007 @default.
• W4328143758 cites W2587499203 @default.
• W4328143758 cites W2730275777 @default.
• W4328143758 cites W2766251233 @default.
• W4328143758 cites W2789775171 @default.
• W4328143758 cites W2797273007 @default.
• W4328143758 cites W2804472076 @default.
• W4328143758 cites W2982419136 @default.
• W4328143758 cites W2999763796 @default.
• W4328143758 cites W3006041608 @default.
• W4328143758 cites W3131498895 @default.
• W4328143758 cites W4200158835 @default.
• W4328143758 cites W4251002148 @default.
• W4328143758 cites W4295021235 @default.
• W4328143758 cites W4295755819 @default.
• W4328143758 doi "https://doi.org/10.1093/pm/pnad040" @default.
• W4328143758 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36946277" @default.
• W4328143758 hasPublicationYear "2023" @default.
• W4328143758 type Work @default.
• W4328143758 citedByCount "0" @default.
• W4328143758 crossrefType "journal-article" @default.
• W4328143758 hasAuthorship W4328143758A5012717312 @default.
• W4328143758 hasAuthorship W4328143758A5020251712 @default.
• W4328143758 hasAuthorship W4328143758A5032775119 @default.
• W4328143758 hasAuthorship W4328143758A5035220104 @default.
• W4328143758 hasAuthorship W4328143758A5064369545 @default.
• W4328143758 hasAuthorship W4328143758A5069598374 @default.
• W4328143758 hasAuthorship W4328143758A5076930866 @default.
• W4328143758 hasAuthorship W4328143758A5087223695 @default.
• W4328143758 hasAuthorship W4328143758A5091449737 @default.
• W4328143758 hasBestOaLocation W43281437581 @default.
• W4328143758 hasConcept C126322002 @default.
• W4328143758 hasConcept C15490471 @default.
• W4328143758 hasConcept C170493617 @default.
• W4328143758 hasConcept C1862650 @default.
• W4328143758 hasConcept C203014093 @default.
• W4328143758 hasConcept C24998067 @default.
• W4328143758 hasConcept C2776217527 @default.
• W4328143758 hasConcept C2779245659 @default.
• W4328143758 hasConcept C2780226346 @default.
• W4328143758 hasConcept C2781118164 @default.
• W4328143758 hasConcept C3019020247 @default.
• W4328143758 hasConcept C3673659 @default.
• W4328143758 hasConcept C42219234 @default.

• next