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- W432896320 abstract "There are several prognostic factors available today that can be used to guide the treatment decision for patients with early breast cancer. These include axillary lymph node status, tumor size, histopathologic classification, histologic and nuclear grade, estrogen receptors, progesterone receptors, age or menopausal status, DNA ploidy and proliferation. The latest generation of prognostic factors includes measures of proliferation, oncoproteins and growth factors, tumor suppressor genes, invasion-related factors, and heat shock proteins. It must be stressed that these newer factors are still being evaluated and that validation studies are required before they can be considered routine and used in the clinical decision making process. The challenge for the future is to investigate methods for combining prognostic factors into prognostic indices that can be used to accurately estimate the probability of disease recurrence and death, and to predict the likelihood that a patient will benefit from a particular therapy." @default.
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- W432896320 date "1993-01-01" @default.
- W432896320 modified "2023-09-22" @default.
- W432896320 title "Biological Factors and Treatment Decision in Early Breast Cancer" @default.
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- W432896320 doi "https://doi.org/10.1007/978-3-0348-5663-8_38" @default.
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