Matches in SemOpenAlex for { <https://semopenalex.org/work/W43353477> ?p ?o ?g. }
- W43353477 abstract "The discovery and development of truly atypical psychotropic agents are by far more challenging endeavors than synthesizing an additional member of a prototypical class of compounds and demonstrating that it retains a desired pharmacological profile. The identification of novel molecules with potential for clinical application is often hampered by the preconceived notions of structure-activity requirements, desired neurochemical effects, and empirically validated behavioral predictors of clinical success that comfort those seeking to develop second generations of an existing class of drug. Despite dramatic progress in the neurosciences, we still do not understand the biological bases of psychopathology enough to design drugs that will selectively reverse those aberrant states of neural activity that are associated with many disorders. Rather, in order to rationally conceptualize future avenues of pharmacotherapy, we must rely upon imperfect, evolving knowledge about disease states and inferences we may make based upon a similarly incomplete appreciation of the mechanism of action of drugs known to be effective against clinical targets." @default.
- W43353477 created "2016-06-24" @default.
- W43353477 creator A5026646159 @default.
- W43353477 creator A5029656625 @default.
- W43353477 creator A5075523817 @default.
- W43353477 date "1987-01-01" @default.
- W43353477 modified "2023-09-27" @default.
- W43353477 title "Atypical Psychotropic Agents" @default.
- W43353477 cites W1569920182 @default.
- W43353477 cites W1812428887 @default.
- W43353477 cites W1967847807 @default.
- W43353477 cites W1973016997 @default.
- W43353477 cites W1975778556 @default.
- W43353477 cites W1976786012 @default.
- W43353477 cites W1979999228 @default.
- W43353477 cites W1980833292 @default.
- W43353477 cites W1987711435 @default.
- W43353477 cites W1988695831 @default.
- W43353477 cites W1988791558 @default.
- W43353477 cites W1998279837 @default.
- W43353477 cites W2001705681 @default.
- W43353477 cites W2002224654 @default.
- W43353477 cites W2014450118 @default.
- W43353477 cites W2024227811 @default.
- W43353477 cites W2027928253 @default.
- W43353477 cites W2030191470 @default.
- W43353477 cites W2030929730 @default.
- W43353477 cites W2040791771 @default.
- W43353477 cites W2047894009 @default.
- W43353477 cites W2054932753 @default.
- W43353477 cites W2055365557 @default.
- W43353477 cites W2057304728 @default.
- W43353477 cites W2060337783 @default.
- W43353477 cites W2062530420 @default.
- W43353477 cites W2062546678 @default.
- W43353477 cites W2062899996 @default.
- W43353477 cites W2064832285 @default.
- W43353477 cites W2067826296 @default.
- W43353477 cites W2078971066 @default.
- W43353477 cites W2082833382 @default.
- W43353477 cites W2086193772 @default.
- W43353477 cites W2086370837 @default.
- W43353477 cites W2091376353 @default.
- W43353477 cites W2140506109 @default.
- W43353477 cites W2155873994 @default.
- W43353477 cites W4238532820 @default.
- W43353477 cites W4250814507 @default.
- W43353477 doi "https://doi.org/10.1007/978-1-4612-4828-6_14" @default.
- W43353477 hasPublicationYear "1987" @default.
- W43353477 type Work @default.
- W43353477 sameAs 43353477 @default.
- W43353477 citedByCount "2" @default.
- W43353477 crossrefType "book-chapter" @default.
- W43353477 hasAuthorship W43353477A5026646159 @default.
- W43353477 hasAuthorship W43353477A5029656625 @default.
- W43353477 hasAuthorship W43353477A5075523817 @default.
- W43353477 hasConcept C111472728 @default.
- W43353477 hasConcept C116834253 @default.
- W43353477 hasConcept C118552586 @default.
- W43353477 hasConcept C121332964 @default.
- W43353477 hasConcept C123273963 @default.
- W43353477 hasConcept C138885662 @default.
- W43353477 hasConcept C154945302 @default.
- W43353477 hasConcept C15744967 @default.
- W43353477 hasConcept C169760540 @default.
- W43353477 hasConcept C180747234 @default.
- W43353477 hasConcept C188147891 @default.
- W43353477 hasConcept C25876315 @default.
- W43353477 hasConcept C2777212361 @default.
- W43353477 hasConcept C2780035454 @default.
- W43353477 hasConcept C2780791683 @default.
- W43353477 hasConcept C2909703345 @default.
- W43353477 hasConcept C2993714069 @default.
- W43353477 hasConcept C41008148 @default.
- W43353477 hasConcept C542102704 @default.
- W43353477 hasConcept C59822182 @default.
- W43353477 hasConcept C62520636 @default.
- W43353477 hasConcept C71924100 @default.
- W43353477 hasConcept C86803240 @default.
- W43353477 hasConcept C89611455 @default.
- W43353477 hasConceptScore W43353477C111472728 @default.
- W43353477 hasConceptScore W43353477C116834253 @default.
- W43353477 hasConceptScore W43353477C118552586 @default.
- W43353477 hasConceptScore W43353477C121332964 @default.
- W43353477 hasConceptScore W43353477C123273963 @default.
- W43353477 hasConceptScore W43353477C138885662 @default.
- W43353477 hasConceptScore W43353477C154945302 @default.
- W43353477 hasConceptScore W43353477C15744967 @default.
- W43353477 hasConceptScore W43353477C169760540 @default.
- W43353477 hasConceptScore W43353477C180747234 @default.
- W43353477 hasConceptScore W43353477C188147891 @default.
- W43353477 hasConceptScore W43353477C25876315 @default.
- W43353477 hasConceptScore W43353477C2777212361 @default.
- W43353477 hasConceptScore W43353477C2780035454 @default.
- W43353477 hasConceptScore W43353477C2780791683 @default.
- W43353477 hasConceptScore W43353477C2909703345 @default.
- W43353477 hasConceptScore W43353477C2993714069 @default.
- W43353477 hasConceptScore W43353477C41008148 @default.
- W43353477 hasConceptScore W43353477C542102704 @default.
- W43353477 hasConceptScore W43353477C59822182 @default.