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- W43392601 abstract "In this chapter, the focus is on the application of decision analytic tools to assist in reimbursement decisions related to drugs for rare diseases. Focus is on the evaluative framework developed by the Ontario Ministry of Health's Drugs for Rare Diseases Working Group. The chapter describes the framework and illustrates the role of decision analytic methods through the application of the framework to idursulfase treatment of Hunter disease, an enzyme deficiency syndrome. The chapter highlights the development of a Markov model designed to mirror the natural disease history and to simulate the possible benefits of treatment. This process led to the Ministry of Health developing funding recommendations for the treatment of Hunter disease." @default.
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- W43392601 date "2013-01-01" @default.
- W43392601 modified "2023-10-17" @default.
- W43392601 title "Application of Operations Research to Funding Decisions for Treatments with Rare Disease" @default.
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- W43392601 doi "https://doi.org/10.1007/978-1-4614-6507-2_13" @default.
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