FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W43432018> ?p ?o ?g. }

• W43432018 abstract "Rheumatoid arthritis (RA) is a complex, multi-system disease whose primary site of inflammatory tissue damage is the joint. The increasing evidences indicate that activated RA fibroblast-like synoviocytes (FLS) play a critical role in the development of pannus by migrating into cartilage and bone. Furthermore FLS and T cells can activate each other in vitro and in vivo, which is crucial for the progress of RA. Deoxycytidine kinase (DCK) has been linked to peripheral T cell homeostatic proliferation and survival, which is very important for RA. Yet, the function of DCK in FLS is still unknown. Here, we present a story that DCK could regulate the migration and invasion of FLS through AKT pathway in RA patients. Moreover, DCK seems to be the upstream of AKT and FAK, and AKT inhibitor exerted the similar effect on FLS motility. In summary, our study characterized the new role of DCK in human primary FLS cells, and figured out the possible pathway DCK involved in, and these findings might propose DCK as a novel target for controlling joint destruction of RA." @default.
• W43432018 created "2016-06-24" @default.
• W43432018 creator A5034417510 @default.
• W43432018 creator A5051340655 @default.
• W43432018 creator A5063302131 @default.
• W43432018 creator A5069030575 @default.
• W43432018 creator A5070902065 @default.
• W43432018 date "2013-01-01" @default.
• W43432018 modified "2023-09-27" @default.
• W43432018 title "Deoxycytidine kinase promotes the migration and invasion of fibroblast-like synoviocytes from rheumatoid arthritis patients." @default.
• W43432018 cites W1493676054 @default.
• W43432018 cites W1523015364 @default.
• W43432018 cites W1544193757 @default.
• W43432018 cites W1600792033 @default.
• W43432018 cites W1617532721 @default.
• W43432018 cites W1929023701 @default.
• W43432018 cites W1963841183 @default.
• W43432018 cites W1964825240 @default.
• W43432018 cites W1967830103 @default.
• W43432018 cites W1970037245 @default.
• W43432018 cites W1983559242 @default.
• W43432018 cites W1993216157 @default.
• W43432018 cites W1997131908 @default.
• W43432018 cites W1999516176 @default.
• W43432018 cites W2002593275 @default.
• W43432018 cites W2003284223 @default.
• W43432018 cites W2008453146 @default.
• W43432018 cites W2009069048 @default.
• W43432018 cites W2009775095 @default.
• W43432018 cites W2010938999 @default.
• W43432018 cites W2014613440 @default.
• W43432018 cites W2019464570 @default.
• W43432018 cites W2022822197 @default.
• W43432018 cites W2024412592 @default.
• W43432018 cites W2025851689 @default.
• W43432018 cites W2041607472 @default.
• W43432018 cites W2043268172 @default.
• W43432018 cites W2046061313 @default.
• W43432018 cites W2048209624 @default.
• W43432018 cites W2051846980 @default.
• W43432018 cites W2053785734 @default.
• W43432018 cites W2063370298 @default.
• W43432018 cites W2065467422 @default.
• W43432018 cites W2066336622 @default.
• W43432018 cites W2071531606 @default.
• W43432018 cites W2078836325 @default.
• W43432018 cites W2085808988 @default.
• W43432018 cites W2096948545 @default.
• W43432018 cites W2117333246 @default.
• W43432018 cites W2135238116 @default.
• W43432018 cites W2140954528 @default.
• W43432018 cites W2149469915 @default.
• W43432018 cites W2152348310 @default.
• W43432018 cites W2170146627 @default.
• W43432018 cites W2196454906 @default.
• W43432018 cites W2336588424 @default.
• W43432018 cites W2411150599 @default.
• W43432018 cites W2951333149 @default.
• W43432018 cites W46650105 @default.
• W43432018 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3843254" @default.
• W43432018 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24294360" @default.
• W43432018 hasPublicationYear "2013" @default.
• W43432018 type Work @default.
• W43432018 sameAs 43432018 @default.
• W43432018 citedByCount "9" @default.
• W43432018 countsByYear W434320182015 @default.
• W43432018 countsByYear W434320182016 @default.
• W43432018 countsByYear W434320182017 @default.
• W43432018 countsByYear W434320182018 @default.
• W43432018 countsByYear W434320182022 @default.
• W43432018 crossrefType "journal-article" @default.
• W43432018 hasAuthorship W43432018A5034417510 @default.
• W43432018 hasAuthorship W43432018A5051340655 @default.
• W43432018 hasAuthorship W43432018A5063302131 @default.
• W43432018 hasAuthorship W43432018A5069030575 @default.
• W43432018 hasAuthorship W43432018A5070902065 @default.
• W43432018 hasConcept C104317684 @default.
• W43432018 hasConcept C126322002 @default.
• W43432018 hasConcept C127561419 @default.
• W43432018 hasConcept C150903083 @default.
• W43432018 hasConcept C202751555 @default.
• W43432018 hasConcept C207001950 @default.
• W43432018 hasConcept C2776694085 @default.
• W43432018 hasConcept C2777844706 @default.
• W43432018 hasConcept C2779268695 @default.
• W43432018 hasConcept C2780258809 @default.
• W43432018 hasConcept C2780381497 @default.
• W43432018 hasConcept C502942594 @default.
• W43432018 hasConcept C55493867 @default.
• W43432018 hasConcept C62478195 @default.
• W43432018 hasConcept C71924100 @default.
• W43432018 hasConcept C75217442 @default.
• W43432018 hasConcept C86554907 @default.
• W43432018 hasConcept C86803240 @default.
• W43432018 hasConcept C95444343 @default.
• W43432018 hasConceptScore W43432018C104317684 @default.
• W43432018 hasConceptScore W43432018C126322002 @default.
• W43432018 hasConceptScore W43432018C127561419 @default.
• W43432018 hasConceptScore W43432018C150903083 @default.
• W43432018 hasConceptScore W43432018C202751555 @default.

• next