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- W435281328 abstract "This study was meant to explore whether the coupling strength and direction of resting-state electroencephalogram (rsEEG) could be used as an indicator to distinguish the patients of type 2 diabetes mellitus (T2DM) with or without amnestic mild cognitive impairment (aMCI).Permutation conditional mutual information (PCMI) was used to calculate the coupling strength and direction of rsEEG signals between different brain areas of 19 aMCI and 20 normal control (NC) with T2DM on 7 frequency bands: Delta, Theta, Alpha1, Alpha2, Beta1, Beta2 and Gamma. The difference in coupling strength or direction of rsEEG between two groups was calculated. The correlation between coupling strength or direction of rsEEG and score of different neuropsychology scales were also calculated.We have demonstrated that PCMI can calculate effectively the coupling strength and directionality of EEG signals between different brain regions. The significant difference in coupling strength and directionality of EEG signals was found between the patients of aMCI and NC with T2DM on different brain regions. There also existed significant correlation between sex or age and coupling strength or coupling directionality of EEG signals between a few different brain regions from all subjects.The coupling strength or directionality of EEG signals calculated by PCMI are significantly different between aMCI and NC with T2DM.These results showed that the coupling strength or directionality of EEG signals calculated by PCMI might be used as a biomarker in distinguishing the aMCI from NC with T2DM." @default.
- W435281328 created "2016-06-24" @default.
- W435281328 creator A5015626959 @default.
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- W435281328 date "2016-01-01" @default.
- W435281328 modified "2023-10-15" @default.
- W435281328 title "Resting-state EEG coupling analysis of amnestic mild cognitive impairment with type 2 diabetes mellitus by using permutation conditional mutual information" @default.
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- W435281328 doi "https://doi.org/10.1016/j.clinph.2015.05.016" @default.
- W435281328 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26142876" @default.
- W435281328 hasPublicationYear "2016" @default.
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