FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4353021314> ?p ?o ?g. }

• W4353021314 endingPage "e40595" @default.
• W4353021314 startingPage "e40595" @default.
• W4353021314 abstract "Clinical guidelines recommend regular serum lithium monitoring every 3 to 6 months. However, in the real world, only a minority of patients receive adequate monitoring.This study aims to examine whether the use of the electronic health record (EHR)-nested reminder system for serum lithium monitoring can help achieve serum lithium concentrations within the therapeutic range for patients on lithium maintenance therapy.We conducted an unblinded, single-center, EHR-nested, parallel-group, superiority randomized controlled trial comparing EHR-nested reminders with usual care in adult patients receiving lithium maintenance therapy for mood disorders. The primary outcome was the achievement of therapeutically appropriate serum lithium levels between 0.4 and 1.0 mEq/L at 18 months after enrollment. The key secondary outcomes are included as follows: the number of serum lithium level monitoring except for the first and final monitoring; exacerbation of the mood disorder during the study period, defined by hospitalization, increase in lithium dose, addition of antipsychotic drugs or mood stabilizers, or addition or increase of antidepressants; adherence defined by the proportion of days covered by lithium carbonate prescription during the study period.A total of 111 patients were enrolled in this study. A total of 56 patients were assigned to the reminder group, and 55 patients were assigned to the usual care group. At the follow-up, 38 (69.1%) patients in the reminder group and 33 (60.0%) patients in the usual care group achieved the primary outcome (odds ratio 2.14, 95% CI 0.82-5.58, P=.12). The median number of serum lithium monitoring was 2 in the reminder group and 0 in the usual care group (rate ratio 3.62; 95% CI 2.47-5.29, P<.001). The exacerbation of mood disorders occurred in 17 (31.5%) patients in the reminder group and in 16 (34.8%) patients in the usual care group (odds ratio 0.97, 95% CI 0.42-2.28, P=.95).We found insufficient evidence for an EHR-nested reminder to increase the achievement of therapeutic serum lithium concentrations. However, the number of monitoring increased with relatively simple and inexpensive intervention. The EHR-based reminders may be useful to improve quality of care for patients on lithium maintenance therapy, and they have potentials to be applied to other problems.University Hospital Medical Information Network Clinical Trials Registry UMIN000033633; https://tinyurl.com/5n7wtyav." @default.
• W4353021314 created "2023-03-23" @default.
• W4353021314 creator A5024391764 @default.
• W4353021314 creator A5037731704 @default.
• W4353021314 creator A5039059635 @default.
• W4353021314 creator A5046924080 @default.
• W4353021314 creator A5047922226 @default.
• W4353021314 creator A5054227064 @default.
• W4353021314 creator A5057664074 @default.
• W4353021314 creator A5064682866 @default.
• W4353021314 creator A5064755492 @default.
• W4353021314 creator A5066538433 @default.
• W4353021314 creator A5071622311 @default.
• W4353021314 creator A5081339326 @default.
• W4353021314 creator A5082940042 @default.
• W4353021314 creator A5085050194 @default.
• W4353021314 date "2023-03-22" @default.
• W4353021314 modified "2023-10-01" @default.
• W4353021314 title "Electronic Health Record–Nested Reminders for Serum Lithium Level Monitoring in Patients With Mood Disorder: Randomized Controlled Trial" @default.
• W4353021314 cites W1516930466 @default.
• W4353021314 cites W1866730877 @default.
• W4353021314 cites W1967221244 @default.
• W4353021314 cites W2003490971 @default.
• W4353021314 cites W2005799519 @default.
• W4353021314 cites W2011293135 @default.
• W4353021314 cites W2012476442 @default.
• W4353021314 cites W2013089450 @default.
• W4353021314 cites W2027243048 @default.
• W4353021314 cites W2049103906 @default.
• W4353021314 cites W2062644160 @default.
• W4353021314 cites W2065974896 @default.
• W4353021314 cites W2070589693 @default.
• W4353021314 cites W2097692034 @default.
• W4353021314 cites W2148794355 @default.
• W4353021314 cites W2559918497 @default.
• W4353021314 cites W2789781429 @default.
• W4353021314 cites W2792027821 @default.
• W4353021314 cites W2901905689 @default.
• W4353021314 cites W2904994736 @default.
• W4353021314 cites W2995031950 @default.
• W4353021314 cites W3029320863 @default.
• W4353021314 cites W3123501659 @default.
• W4353021314 doi "https://doi.org/10.2196/40595" @default.
• W4353021314 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36947138" @default.
• W4353021314 hasPublicationYear "2023" @default.
• W4353021314 type Work @default.
• W4353021314 citedByCount "0" @default.
• W4353021314 crossrefType "journal-article" @default.
• W4353021314 hasAuthorship W4353021314A5024391764 @default.
• W4353021314 hasAuthorship W4353021314A5037731704 @default.
• W4353021314 hasAuthorship W4353021314A5039059635 @default.
• W4353021314 hasAuthorship W4353021314A5046924080 @default.
• W4353021314 hasAuthorship W4353021314A5047922226 @default.
• W4353021314 hasAuthorship W4353021314A5054227064 @default.
• W4353021314 hasAuthorship W4353021314A5057664074 @default.
• W4353021314 hasAuthorship W4353021314A5064682866 @default.
• W4353021314 hasAuthorship W4353021314A5064755492 @default.
• W4353021314 hasAuthorship W4353021314A5066538433 @default.
• W4353021314 hasAuthorship W4353021314A5071622311 @default.
• W4353021314 hasAuthorship W4353021314A5081339326 @default.
• W4353021314 hasAuthorship W4353021314A5082940042 @default.
• W4353021314 hasAuthorship W4353021314A5085050194 @default.
• W4353021314 hasBestOaLocation W43530213141 @default.
• W4353021314 hasConcept C118552586 @default.
• W4353021314 hasConcept C121332964 @default.
• W4353021314 hasConcept C126322002 @default.
• W4353021314 hasConcept C145148216 @default.
• W4353021314 hasConcept C156957248 @default.
• W4353021314 hasConcept C165617652 @default.
• W4353021314 hasConcept C168563851 @default.
• W4353021314 hasConcept C187212893 @default.
• W4353021314 hasConcept C2182769 @default.
• W4353021314 hasConcept C2776174506 @default.
• W4353021314 hasConcept C2776412080 @default.
• W4353021314 hasConcept C2777014857 @default.
• W4353021314 hasConcept C2778541603 @default.
• W4353021314 hasConcept C2780494398 @default.
• W4353021314 hasConcept C2780550438 @default.
• W4353021314 hasConcept C2780733359 @default.
• W4353021314 hasConcept C2781046926 @default.
• W4353021314 hasConcept C62520636 @default.
• W4353021314 hasConcept C71924100 @default.
• W4353021314 hasConceptScore W4353021314C118552586 @default.
• W4353021314 hasConceptScore W4353021314C121332964 @default.
• W4353021314 hasConceptScore W4353021314C126322002 @default.
• W4353021314 hasConceptScore W4353021314C145148216 @default.
• W4353021314 hasConceptScore W4353021314C156957248 @default.
• W4353021314 hasConceptScore W4353021314C165617652 @default.
• W4353021314 hasConceptScore W4353021314C168563851 @default.
• W4353021314 hasConceptScore W4353021314C187212893 @default.
• W4353021314 hasConceptScore W4353021314C2182769 @default.
• W4353021314 hasConceptScore W4353021314C2776174506 @default.
• W4353021314 hasConceptScore W4353021314C2776412080 @default.
• W4353021314 hasConceptScore W4353021314C2777014857 @default.
• W4353021314 hasConceptScore W4353021314C2778541603 @default.
• W4353021314 hasConceptScore W4353021314C2780494398 @default.
• W4353021314 hasConceptScore W4353021314C2780550438 @default.
• W4353021314 hasConceptScore W4353021314C2780733359 @default.

• next