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- W4353036290 abstract "Abstract Covid-19 has spurred a renewed interest at decontamination techniques for air, objects and surfaces. Beginning 2020, a lot of effort was done in urgency to permit the reuse of UC-V for inactivating SARS-CoV-2. However, those studies diverged widely on the dose necessary to reach this goal; until today, the real value of the sensitivity of the virus to a 254-nm illumination is not known precisely. In this study, decontamination was performed in an original UV-C large decontamination chamber (UVCab, ON-LIGHT, France) delivering an omnidirectional irradiation with an average dose of 50 mJ/cm 2 in 60 sec. Viral inactivation was checked by both cell culture and PCR test. SARS-CoV-2 was inactivated by UV-C light within 3 sec on both porous (disposable gown) and non-porous (stainless steel and apron) surfaces. For the porous surface, an irradiation of 5 min was needed to completely negative the PCR signal. The Z value estimating the sensitivity of SARS-CoV-2 to UV-C in the experimental conditions of our cabinet was shown to be > 0.5820 m 2 /J. These results illustrate the ability of this apparatus to inactivate rapidly and definitively high loads of SARS-CoV-2 deposited on porous or non-porous supports and open new perspectives on material decontamination using UV-C." @default.
- W4353036290 created "2023-03-23" @default.
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- W4353036290 date "2023-03-22" @default.
- W4353036290 modified "2023-09-24" @default.
- W4353036290 title "Ultrafast inactivation of SARS-CoV-2 by 254-nm UV-C irradiation on porous and non-porous media of medical interest using an omnidirectional chamber" @default.
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- W4353036290 doi "https://doi.org/10.21203/rs.3.rs-2643818/v1" @default.
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