FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4360600506> ?p ?o ?g. }

• W4360600506 abstract "BACKGROUND: Evidence surrounding P2Y12 platelet reactivity units (PRU) impact on bleeding outcomes in patients undergoing coronary artery bypass is varied. This study sought to assess whether on-pump CABG procedures result in increased bleeding in patients with high compared to low PRUs.METHODS: This retrospective cohort study compared those with a PRU level ≤237 (low PRU group) to >237 (high PRU group). The primary outcome assessed massive or severe bleeding in accordance with universal definition of perioperative bleeding criteria. Secondary outcomes assessed mortality, length of stay and relevant bleeding related outcomes (e.g., rates of moderate or lower classifications of bleeding, chest tube output, blood product receipt).RESULTS: A total of 69 patients were included, 47 in the low and 22 in the high PRU groups. Patients were a median (IQR) 66 (62-74) years and 84.1% (N.=58) were male. Most patients received clopidogrel prior to procedure (39 [83%] in low and 18 [81.8%] in high PRU group; P=1.0000). The rate of the primary outcome was 14.9% (N.=7) in patients with a low PRU and 18.2% (N.=4) in patients with a high PRU; P=0.7345. The rate of moderate bleeding was 59.6% (N.=28) in the low and 27.3% (N.=6) in the high PRU group (P=0.0124). Packed red blood cells (PRBCs) were administered to more patients in the low (23 [48.9%]) than the high PRU group (2 [22.7%]; P=0.0388). There were no differences in other blood product requirement, chest tube output, factor products administered, mortality, or length of stay.CONCLUSIONS: This study determined that low preoperative P2Y12 PRU levels may influence moderate bleeding in patients undergoing cardiac surgery, but not massive or severe bleeding." @default.
• W4360600506 created "2023-03-24" @default.
• W4360600506 creator A5012643048 @default.
• W4360600506 creator A5013185123 @default.
• W4360600506 creator A5019560829 @default.
• W4360600506 creator A5029989635 @default.
• W4360600506 creator A5056104158 @default.
• W4360600506 creator A5088815377 @default.
• W4360600506 date "2023-07-01" @default.
• W4360600506 modified "2023-09-30" @default.
• W4360600506 title "Effect of P2Y12 platelet reactivity level on peri- and postoperative outcomes of cardiac surgery patients" @default.
• W4360600506 cites W110732833 @default.
• W4360600506 cites W1543191655 @default.
• W4360600506 cites W1963019726 @default.
• W4360600506 cites W1998899422 @default.
• W4360600506 cites W2013204694 @default.
• W4360600506 cites W2030244779 @default.
• W4360600506 cites W2036384654 @default.
• W4360600506 cites W2049036705 @default.
• W4360600506 cites W2057581104 @default.
• W4360600506 cites W2107522704 @default.
• W4360600506 cites W2110108344 @default.
• W4360600506 cites W2114879453 @default.
• W4360600506 cites W2132547422 @default.
• W4360600506 cites W2162879297 @default.
• W4360600506 cites W2171807722 @default.
• W4360600506 cites W2272541304 @default.
• W4360600506 cites W2766941490 @default.
• W4360600506 cites W3132730908 @default.
• W4360600506 cites W4205357827 @default.
• W4360600506 doi "https://doi.org/10.23736/s0021-9509.23.12595-x" @default.
• W4360600506 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36951689" @default.
• W4360600506 hasPublicationYear "2023" @default.
• W4360600506 type Work @default.
• W4360600506 citedByCount "0" @default.
• W4360600506 crossrefType "journal-article" @default.
• W4360600506 hasAuthorship W4360600506A5012643048 @default.
• W4360600506 hasAuthorship W4360600506A5013185123 @default.
• W4360600506 hasAuthorship W4360600506A5019560829 @default.
• W4360600506 hasAuthorship W4360600506A5029989635 @default.
• W4360600506 hasAuthorship W4360600506A5056104158 @default.
• W4360600506 hasAuthorship W4360600506A5088815377 @default.
• W4360600506 hasConcept C126322002 @default.
• W4360600506 hasConcept C141071460 @default.
• W4360600506 hasConcept C167135981 @default.
• W4360600506 hasConcept C2777396833 @default.
• W4360600506 hasConcept C2777849778 @default.
• W4360600506 hasConcept C2778789114 @default.
• W4360600506 hasConcept C31174226 @default.
• W4360600506 hasConcept C49059817 @default.
• W4360600506 hasConcept C500558357 @default.
• W4360600506 hasConcept C71924100 @default.
• W4360600506 hasConcept C89560881 @default.
• W4360600506 hasConcept C90924648 @default.
• W4360600506 hasConceptScore W4360600506C126322002 @default.
• W4360600506 hasConceptScore W4360600506C141071460 @default.
• W4360600506 hasConceptScore W4360600506C167135981 @default.
• W4360600506 hasConceptScore W4360600506C2777396833 @default.
• W4360600506 hasConceptScore W4360600506C2777849778 @default.
• W4360600506 hasConceptScore W4360600506C2778789114 @default.
• W4360600506 hasConceptScore W4360600506C31174226 @default.
• W4360600506 hasConceptScore W4360600506C49059817 @default.
• W4360600506 hasConceptScore W4360600506C500558357 @default.
• W4360600506 hasConceptScore W4360600506C71924100 @default.
• W4360600506 hasConceptScore W4360600506C89560881 @default.
• W4360600506 hasConceptScore W4360600506C90924648 @default.
• W4360600506 hasIssue "4" @default.
• W4360600506 hasLocation W43606005061 @default.
• W4360600506 hasLocation W43606005062 @default.
• W4360600506 hasOpenAccess W4360600506 @default.
• W4360600506 hasPrimaryLocation W43606005061 @default.
• W4360600506 hasRelatedWork W186366351 @default.
• W4360600506 hasRelatedWork W2116611908 @default.
• W4360600506 hasRelatedWork W2163779553 @default.
• W4360600506 hasRelatedWork W2235698526 @default.
• W4360600506 hasRelatedWork W2592711088 @default.
• W4360600506 hasRelatedWork W2597068225 @default.
• W4360600506 hasRelatedWork W2792749019 @default.
• W4360600506 hasRelatedWork W2990858970 @default.
• W4360600506 hasRelatedWork W4381741209 @default.
• W4360600506 hasRelatedWork W3006168697 @default.
• W4360600506 hasVolume "64" @default.
• W4360600506 isParatext "false" @default.
• W4360600506 isRetracted "false" @default.
• W4360600506 workType "article" @default.