FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4360600855> ?p ?o ?g. }

• W4360600855 endingPage "513" @default.
• W4360600855 startingPage "503" @default.
• W4360600855 abstract "Abstract Introduction: Paediatric heart failure is a common clinical syndrome that may be experienced by children with congenital heart disease (CHD) and/or cardiomyopathy. It is characterised by clinical signs/symptoms which reflect the underlying pathophysiology based on one of three main clinical states: Pulmonary over-circulation, pressure overload, and ventricular failure. Current diagnosis relies on clinical assessment and echocardiogram imaging as cardiac biomarkers has been predominantly scientific to date. This review provides a comprehensive overview of paediatric heart failure pathophysiology and considers the available evidence for cardiac biomarkers in this setting. Methods: A literature review was completed using MEDLINE ALL, EMBASE, and PubMed on 10th November, 2022. Search terms included biomarkers, heart failure, heart defects, congenital heart disease, fontan circulation, single ventricle circulation, cardiomyopathy, and child. This allowed the identification of individual cardiac biomarkers which are the focus of this review. These included NT-proBNP, MR-proANP, MR-proADM, troponin, sST2, galectin 3, and growth differentiation factor-15. Results: Paediatric studies have established reference ranges for NT-proBNP and troponin for children with structurally normal hearts. Of all the biomarkers reviewed, NT-proBNP appears to correlate most closely with symptoms of heart failure and ventricular dysfunction on echocardiogram. However, there remains limited longitudinal data for NT-proBNP, and no validated reference ranges for patients with CHD and/or cardiomyopathy. None of the other biomarkers reviewed were consistently superior to NT-proBNP. Conclusion: Further large paediatric studies of patients with heart failure are needed to validate NT-proBNP in CHD and to evaluate the role of novel biomarkers in specific types of CHD, e.g. single ventricle physiology." @default.
• W4360600855 created "2023-03-24" @default.
• W4360600855 creator A5020725070 @default.
• W4360600855 creator A5052868080 @default.
• W4360600855 creator A5067734684 @default.
• W4360600855 creator A5089396457 @default.
• W4360600855 date "2023-03-23" @default.
• W4360600855 modified "2023-09-30" @default.
• W4360600855 title "Paediatric heart failure – understanding the pathophysiology and the current role of cardiac biomarkers in clinical practice" @default.
• W4360600855 cites W120710316 @default.
• W4360600855 cites W1484012023 @default.
• W4360600855 cites W1547316933 @default.
• W4360600855 cites W1553252776 @default.
• W4360600855 cites W1973182747 @default.
• W4360600855 cites W1977566662 @default.
• W4360600855 cites W1981722559 @default.
• W4360600855 cites W1981784273 @default.
• W4360600855 cites W1985696268 @default.
• W4360600855 cites W1991031599 @default.
• W4360600855 cites W1991954488 @default.
• W4360600855 cites W1994391038 @default.
• W4360600855 cites W1997508690 @default.
• W4360600855 cites W2007090944 @default.
• W4360600855 cites W2009377729 @default.
• W4360600855 cites W2010011044 @default.
• W4360600855 cites W2015015831 @default.
• W4360600855 cites W2029087336 @default.
• W4360600855 cites W2038265697 @default.
• W4360600855 cites W2038287301 @default.
• W4360600855 cites W2038322940 @default.
• W4360600855 cites W2043723333 @default.
• W4360600855 cites W2059325661 @default.
• W4360600855 cites W2059384183 @default.
• W4360600855 cites W2073254471 @default.
• W4360600855 cites W2073299934 @default.
• W4360600855 cites W2077919957 @default.
• W4360600855 cites W2078956762 @default.
• W4360600855 cites W2079291178 @default.
• W4360600855 cites W2092587751 @default.
• W4360600855 cites W2095749109 @default.
• W4360600855 cites W2098072787 @default.
• W4360600855 cites W2103507875 @default.
• W4360600855 cites W2122710112 @default.
• W4360600855 cites W2130187982 @default.
• W4360600855 cites W2141316227 @default.
• W4360600855 cites W2144746349 @default.
• W4360600855 cites W2151631274 @default.
• W4360600855 cites W2152922629 @default.
• W4360600855 cites W2153691162 @default.
• W4360600855 cites W2153862535 @default.
• W4360600855 cites W2154258598 @default.
• W4360600855 cites W2155209934 @default.
• W4360600855 cites W2171249645 @default.
• W4360600855 cites W2272844181 @default.
• W4360600855 cites W2275436105 @default.
• W4360600855 cites W2277792196 @default.
• W4360600855 cites W2314627661 @default.
• W4360600855 cites W2346747944 @default.
• W4360600855 cites W2406008672 @default.
• W4360600855 cites W2539774686 @default.
• W4360600855 cites W2545266774 @default.
• W4360600855 cites W2546955765 @default.
• W4360600855 cites W2552901902 @default.
• W4360600855 cites W2615732360 @default.
• W4360600855 cites W2620648363 @default.
• W4360600855 cites W2763316190 @default.
• W4360600855 cites W2769708180 @default.
• W4360600855 cites W2783721837 @default.
• W4360600855 cites W2789951798 @default.
• W4360600855 cites W2805953220 @default.
• W4360600855 cites W2807743405 @default.
• W4360600855 cites W2841828251 @default.
• W4360600855 cites W2884110862 @default.
• W4360600855 cites W2899004553 @default.
• W4360600855 cites W2911661102 @default.
• W4360600855 cites W2921399549 @default.
• W4360600855 cites W2935664338 @default.
• W4360600855 cites W2947468948 @default.
• W4360600855 cites W2949490645 @default.
• W4360600855 cites W2953875223 @default.
• W4360600855 cites W2982400691 @default.
• W4360600855 cites W2982693936 @default.
• W4360600855 cites W3013016292 @default.
• W4360600855 cites W3036499804 @default.
• W4360600855 cites W3040929955 @default.
• W4360600855 cites W3044356150 @default.
• W4360600855 cites W3050342325 @default.
• W4360600855 cites W3089511687 @default.
• W4360600855 cites W3108320502 @default.
• W4360600855 cites W3109575594 @default.
• W4360600855 cites W3124597792 @default.
• W4360600855 cites W3126671150 @default.
• W4360600855 cites W3127550377 @default.
• W4360600855 cites W3130054617 @default.
• W4360600855 cites W3157953231 @default.
• W4360600855 cites W3184156805 @default.
• W4360600855 cites W4200071910 @default.
• W4360600855 cites W4220936830 @default.

• next