Matches in SemOpenAlex for { <https://semopenalex.org/work/W4360600877> ?p ?o ?g. }
- W4360600877 abstract "Abstract Objectives Thymoquinone is a major bioactive compound present in the black seeds of the Nigella sativa . Tendon injuries are almost 50% of all musculoskeletal injuries. The recovery of tendon after surgery has become a significant challenge in orthopedics. Design The purpose of this study was to investigate the healing effect of thymoquinone injections in 40 New Zealand rabbits tendon traumatic models. Materials and methods Tendinopathy was induced by trauma using surgical forceps on the Achilles tendon. Animals were randomly divided into 4 groups: (1) normal saline injection (control), (2) DMSO injection, (3) thymoquinone 5% w/w injection, and (4) thymoquinone 10% w/w injection. Forty-two days after surgery, biochemical and histopathological evaluations were done, and biomechanical evaluation was conducted 70 days after surgery. Results Breakpoint and yield points in treatment groups were significantly higher compared to control and DMSO groups. Hydroxyproline content in the 10% thymoquinone receiving group was higher than all groups. Edema and hemorrhage in the histopathological evaluation were significantly lower in the thymoquinone 10% and thymoquinone 5% receiving groups compared to control and DMSO groups. Collagen fibers, collagen fibers with fibrocytes, and collagen fibers with fibroblasts were significantly higher in the thymoquinone 10% and thymoquinone 5% receiving groups compared to control groups. Conclusions Thymoquinone injection in the tendon in the concentration of 10% w/w is a simple and low-cost healing agent that could enhance mechanical and collagen synthesis in traumatic tendinopathy models in rabbit." @default.
- W4360600877 created "2023-03-24" @default.
- W4360600877 creator A5000239384 @default.
- W4360600877 creator A5014673115 @default.
- W4360600877 creator A5025813997 @default.
- W4360600877 creator A5050983476 @default.
- W4360600877 creator A5080685256 @default.
- W4360600877 date "2023-03-23" @default.
- W4360600877 modified "2023-10-14" @default.
- W4360600877 title "The healing effects of thymoquinone on experimentally induced traumatic tendinopathy in rabbits" @default.
- W4360600877 cites W1500827124 @default.
- W4360600877 cites W1588510477 @default.
- W4360600877 cites W1605888420 @default.
- W4360600877 cites W1820407214 @default.
- W4360600877 cites W1978563348 @default.
- W4360600877 cites W1998788728 @default.
- W4360600877 cites W2005802696 @default.
- W4360600877 cites W2027519024 @default.
- W4360600877 cites W2028115241 @default.
- W4360600877 cites W2054486269 @default.
- W4360600877 cites W2107740232 @default.
- W4360600877 cites W2149142235 @default.
- W4360600877 cites W2159172491 @default.
- W4360600877 cites W2162700482 @default.
- W4360600877 cites W2166648746 @default.
- W4360600877 cites W2172143262 @default.
- W4360600877 cites W2239090104 @default.
- W4360600877 cites W2524757980 @default.
- W4360600877 cites W2610406308 @default.
- W4360600877 cites W2738404635 @default.
- W4360600877 cites W2759364382 @default.
- W4360600877 cites W2771011577 @default.
- W4360600877 cites W2892476927 @default.
- W4360600877 cites W2896582829 @default.
- W4360600877 cites W2902222378 @default.
- W4360600877 cites W2908603454 @default.
- W4360600877 cites W2919287544 @default.
- W4360600877 cites W2970435916 @default.
- W4360600877 cites W2973744859 @default.
- W4360600877 cites W2990548233 @default.
- W4360600877 cites W3046306790 @default.
- W4360600877 cites W3123497340 @default.
- W4360600877 cites W3149170209 @default.
- W4360600877 cites W3161464939 @default.
- W4360600877 cites W3186172092 @default.
- W4360600877 cites W4200054881 @default.
- W4360600877 cites W755401697 @default.
- W4360600877 doi "https://doi.org/10.1186/s13018-023-03706-8" @default.
- W4360600877 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36949516" @default.
- W4360600877 hasPublicationYear "2023" @default.
- W4360600877 type Work @default.
- W4360600877 citedByCount "1" @default.
- W4360600877 countsByYear W43606008772023 @default.
- W4360600877 crossrefType "journal-article" @default.
- W4360600877 hasAuthorship W4360600877A5000239384 @default.
- W4360600877 hasAuthorship W4360600877A5014673115 @default.
- W4360600877 hasAuthorship W4360600877A5025813997 @default.
- W4360600877 hasAuthorship W4360600877A5050983476 @default.
- W4360600877 hasAuthorship W4360600877A5080685256 @default.
- W4360600877 hasBestOaLocation W43606008771 @default.
- W4360600877 hasConcept C126322002 @default.
- W4360600877 hasConcept C141071460 @default.
- W4360600877 hasConcept C185592680 @default.
- W4360600877 hasConcept C2778004101 @default.
- W4360600877 hasConcept C2778911562 @default.
- W4360600877 hasConcept C2779034068 @default.
- W4360600877 hasConcept C2779797417 @default.
- W4360600877 hasConcept C2780105995 @default.
- W4360600877 hasConcept C2780269544 @default.
- W4360600877 hasConcept C2993714443 @default.
- W4360600877 hasConcept C42219234 @default.
- W4360600877 hasConcept C55493867 @default.
- W4360600877 hasConcept C556039675 @default.
- W4360600877 hasConcept C71924100 @default.
- W4360600877 hasConceptScore W4360600877C126322002 @default.
- W4360600877 hasConceptScore W4360600877C141071460 @default.
- W4360600877 hasConceptScore W4360600877C185592680 @default.
- W4360600877 hasConceptScore W4360600877C2778004101 @default.
- W4360600877 hasConceptScore W4360600877C2778911562 @default.
- W4360600877 hasConceptScore W4360600877C2779034068 @default.
- W4360600877 hasConceptScore W4360600877C2779797417 @default.
- W4360600877 hasConceptScore W4360600877C2780105995 @default.
- W4360600877 hasConceptScore W4360600877C2780269544 @default.
- W4360600877 hasConceptScore W4360600877C2993714443 @default.
- W4360600877 hasConceptScore W4360600877C42219234 @default.
- W4360600877 hasConceptScore W4360600877C55493867 @default.
- W4360600877 hasConceptScore W4360600877C556039675 @default.
- W4360600877 hasConceptScore W4360600877C71924100 @default.
- W4360600877 hasIssue "1" @default.
- W4360600877 hasLocation W43606008771 @default.
- W4360600877 hasLocation W43606008772 @default.
- W4360600877 hasLocation W43606008773 @default.
- W4360600877 hasOpenAccess W4360600877 @default.
- W4360600877 hasPrimaryLocation W43606008771 @default.
- W4360600877 hasRelatedWork W2102358242 @default.
- W4360600877 hasRelatedWork W2115960174 @default.
- W4360600877 hasRelatedWork W2166648746 @default.
- W4360600877 hasRelatedWork W2321698694 @default.
- W4360600877 hasRelatedWork W2618643808 @default.
- W4360600877 hasRelatedWork W2921063849 @default.