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- W4360603003 abstract "Despite the potential for mechanical, developmental and/or chemical mechanisms to prevent self-fertilization, incidental self-fertilization is inevitable in many predominantly outcrossing species. In such cases, inbreeding (by self-fertilization or biparental inbreeding) may severely compromise individual fitness by exposing the recessive genetic load, which is otherwise hidden in the heterozygous state. Unquestionably, much of this load is an inevitable consequence of the mutational process and the masking of deleterious recessive alleles in predominantly outcrossing populations. However, we show that when reproductive compensation allows for the replacements of inviable embryos lost early in development, natural selection can favor highly deleterious recessive variants that functionally induce self-sacrificial death of inbred embryos. Our work provides numerous testable hypotheses, and suggests that the distinction between late self-incompatibility and early acting inbreeding depression may be somewhat artificial in some taxa." @default.
- W4360603003 created "2023-03-24" @default.
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- W4360603003 date "2023-03-23" @default.
- W4360603003 modified "2023-10-01" @default.
- W4360603003 title "Early acting inbreeding depression can evolve as an inbreeding avoidance mechanism" @default.
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- W4360603003 doi "https://doi.org/10.1101/2023.03.20.533524" @default.
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